Zu "K11413" wurden 61 Artikel gefunden!
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CAY10721
Artikelnummer: TGM-T35821-10mg
Description: CAY10721 is an inhibitor of sirtuin 3 (SIRT3), a class III HDAC (39% SIRT3 inhibition at 200 µM). Upregulation of SIRT3 transcription is associated with oral squamous cell carcinoma (OSCC) and breast cancer with lymph node involvement, while SIRT3 down-regulation inhibits the growth of OSCC cells and...
| Anwendung: | SIRT3 inhibitor |
| CAS | 848688-62-0 |
| MW: | 351.38 D |
ab 77,00 €
CAY10722
Artikelnummer: TGM-T35822-10mg
Description: CAY10722 is an inhibitor of sirtuin 3 (SIRT3), a class III HDAC (71% inhibition at 200 µM). SIRT3 is involved in modulating metabolic homeostasis as a NAD+-dependent protein deacetylase in the mitochondria. SIRT3 functions as either an oncogene or tumor suppressor, depending on cancer cell type. High...
| Anwendung: | SIRT3 inhibitor |
| CAS | 388086-13-3 |
| MW: | 397.25 D |
ab 340,00 €
3-TYP
Artikelnummer: TGM-T4108-100mg
Description: 3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor. Target: Sirtuin. Smiles: c1[nH]nnc1-c1cccnc1. References: Pi H, et al. SIRT3-SOD2-mROS-dependent autophagy in cadmium-induced hepatotoxicity and salvage by melatonin. Autophagy. 2015,11(7):1037-51
| Schlagworte: | 3-(1H-1,2,3-triazol-4-yl) pyridine |
| Anwendung: | SIRT3 inhibitor |
| CAS | 120241-79-4 |
| MW: | 146.15 D |
ab 52,00 €
SIRT3 Protein, Mouse, Recombinant (His & Myc)
Artikelnummer: TGM-TMPH-02798-100ug
Description: SIRT3 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 36.3 kDa and the accession number is Q8R104.
| Schlagworte: | NAD-dependent protein deacetylase sirtuin-3, SIR2-like protein 3, Regulatory protein SIR2 homolog 3, Sirt3 |
| MW: | 36.3 kD |
ab 352,00 €
NAD-dependent protein deacetylase sirtuin-3,...
Artikelnummer: CSB-EP882102HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 118-399aa. Protein Length: Partial. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: SDKGKLSLQD VAELIRARAC QRVVVMVGAG ISTPSGIPDF RSPGSGLYSN LQQYDLPYPE AIFELPFFFH NPKPFFTLAK ELYPGNYKPN VTHYFLRLLH DKGLLLRLYT QNIDGLERVS GIPASKLVEA HGTFASATCT...
| Schlagworte: | SIRT3, hSIRT3, SIR2L3, SIR2-like protein 3, Regulatory protein SIR2 homolog 3, NAD-dependent protein deacetylase... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 32.3 kD |
ab 240,00 €
NAD-dependent protein deacetylase sirtuin-3 (Sirt3),...
Artikelnummer: CSB-EP848095MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 78-334aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MVGAGISTPS GIPDFRSPGS GLYSNLQQYD IPYPEAIFEL GFFFHNPKPF FMLAKELYPG HYRPNVTHYF LRLLHDKELL LRLYTQNIDG LERASGIPAS KLVEAHGTFV...
| Schlagworte: | Sirt3, Sir2l3, mSIR2L3, SIR2-like protein 3, Regulatory protein SIR2 homolog 3, NAD-dependent protein deacetylase... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 36.3 kD |
ab 354,00 €
NAD-dependent protein deacetylase (Sirt3), rat, recombinant
Artikelnummer: CSB-EP848095RA.1
Organism: Rattus norvegicus (Rat). Source: E.coli. Expression Region: 1-257aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MVGAGISTPS GIPDFRSPGS GLYSNLQQYD IPYPEAIFEL GFFFHNPKPF FTLAKELYPG HYRPNVAHYF LRLLHDKELL LRLYTQNIDG LERASGIPAS KLVEAHGSFV...
| Schlagworte: | NAD-dependent protein deacetylase, Recombinant Rat NAD-dependent protein deacetylase (Sirt3) |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | rat |
| MW: | 35.9 kD |
ab 354,00 €
Anti-SIRT3
Artikelnummer: CSB-PA100396.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SIRT3. Antigen Species: Human
| Schlagworte: | Anti-SIRT3, Anti-SIR2L3, Anti-hSIRT3, Anti-SIR2-like protein 3, Anti-Regulatory protein SIR2 homolog 3, Anti-NAD-dependent... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 163,00 €
Anti-SIRT3
Artikelnummer: CSB-PA229200.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-SIRT3, Anti-SIR2L3, Anti-hSIRT3, Anti-SIR2-like protein 3, Anti-Regulatory protein SIR2 homolog 3, Anti-NAD-dependent... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
275,00 €
Anti-SIRT3
Artikelnummer: CSB-PA937428.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SIRT3. Antigen Species: Human
| Schlagworte: | Anti-SIRT3, Anti-SIR2L3, Anti-hSIRT3, Anti-SIR2-like protein 3, Anti-Regulatory protein SIR2 homolog 3, Anti-NAD-dependent... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 163,00 €
SIRT3 Direct Fluorescent Screening Assay Kit
Artikelnummer: Cay10011566-96
The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) that catalyze a reaction coupling lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose. SIRT3 is a mitochondrial protein that plays a role in metabolic regulation and other cellular...
| Schlagworte: | SIRT3, hSIRT3, SIR2L3, EC=3.5.1.-, SIR2-like protein 3, NAD-dependent deacetylase sirtuin-3, mitochondrial |
| Anwendung: | SIRT3 activator/inhibitor screening |
| Spezies-Reaktivität: | human |
467,00 €
Sirtuin 3, active human recombinant protein
Artikelnummer: BPS-50014
Active human Sirtuin 3 (GenBank Accession No. NM_012239), amino acids 102- 399 with N-terminal GST tag, MW= 59 kDa, expressed in E. coli expression system.
| Schlagworte: | SIRT3, SIR2L3, hSIRT3, SIR2-like protein 3, Regulatory protein SIR2 homolog 3, NAD-dependent protein deacetylase... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 59 kD |
650,00 €