Zu "K11412" wurden 74 Artikel gefunden!
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Anti-SIRT2
Artikelnummer: CSB-PA008284.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-SIRT2, Anti-SIR2L, Anti-SIR2-like protein 2, Anti-Regulatory protein SIR2 homolog 2, Anti-NAD-dependent protein... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
106,00 €
Anti-SIRT2
Artikelnummer: CSB-PA058584.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-SIRT2, Anti-SIR2L, Anti-SIR2-like protein 2, Anti-Regulatory protein SIR2 homolog 2, Anti-NAD-dependent protein... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
275,00 €
Anti-SIRT2
Artikelnummer: CSB-PA088519.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SIRT2. Antigen Species: Human
| Schlagworte: | Anti-SIRT2, Anti-SIR2L, Anti-SIR2-like protein 2, Anti-Regulatory protein SIR2 homolog 2, Anti-NAD-dependent protein... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
Anti-SIRT2
Artikelnummer: CSB-PA157595.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SIRT2. Antigen Species: Human
| Schlagworte: | Anti-SIRT2, Anti-SIR2L, Anti-SIR2-like protein 2, Anti-Regulatory protein SIR2 homolog 2, Anti-NAD-dependent protein... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
Human SIRT2 (Sirtuin 2) ELISA Kit
Artikelnummer: ELK-ELK1537.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SIRT2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SIRT2. Next,...
| Schlagworte: | SIR2L, SIRT2, SIR2-like protein 2, Regulatory protein SIR2 homolog 2, NAD-dependent protein deacetylase sirtuin-2,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Rat SIRT2 (Sirtuin 2) ELISA Kit
Artikelnummer: ELK-ELK5169.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat SIRT2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat SIRT2. Next,...
| Schlagworte: | Sirt2, Sir2l2, SIR2-like protein 2, Regulatory protein SIR2 homolog 2, NAD-dependent protein deacetylase sirtuin-2,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
Tenovin-6 (hydrochloride)
Artikelnummer: Cay13086-1
The tumor suppressor function of p53 hinges on its ability to function as a transcription factor. Tenovin-6 is an analog of tenovin-1, a small molecule activator of p53 transcriptional activity. At 10 µM, this compound is slightly more effective than tenovin-1 at elevating p53 activity in MCF-7 cells and reduces...
| Schlagworte: | N-[[[4-[[5-(dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)-benzamide |
| Anwendung: | SIRT inhibitor |
| CAS | 1011301-29-3 |
| MW: | 491.1 D |
ab 65,00 €
Sirtinol
Artikelnummer: Cay10523-5
Sirtinol is a cell-permeable inhibitor of sirtuin NAD+-dependent deacetylases, inhibiting the yeast sirtuin Sir2p with an IC50 value of 68 µM and the human sirtuins SIRT1 and SIRT2 with IC50 values of 131 and 38 µM, respectively. It does not alter HDAC1 activity. Sirtinol inhibits the growth of cancer cells and...
| Schlagworte: | Sir Two Inhibitor Naphthol, 2-[[(2-hydroxy-1-naphthalenyl)methylene]amino]-N-(1-phenylethyl)-benzamide |
| Anwendung: | Sirtuin inhibitor |
| CAS | 410536-97-9 |
| MW: | 394.5 D |
ab 92,00 €
Tenovin-1
Artikelnummer: Cay13085-10
Tenovin-1 is a small molecule activator of p53 transcriptional activity. At 10 µM, it elevates p53 expression in MCF-7 cells within two hours of treatment and longer-term exposure significantly decreases the growth of BL2 Burkitt's lymphoma and ARN8 melanoma cells. Functioning upstream of p53, tenovin-1 acts by...
| Schlagworte: | N-[[[4-(acetylamino)phenyl]amino]thioxomethyl-4-(1,1-dimethylethyl)]-benzamide |
| Anwendung: | SIRT inhibitor |
| CAS | 380315-80-0 |
| MW: | 369.5 D |
ab 44,00 €
Sirtuin 2, active human recombinant protein
Artikelnummer: BPS-50013
Active human Sirtuin 2, GenBank Accession No. NM_030593, amino acids 13-319 with C-terminal His tag, MW= 35.5 kDa, expressed in E. coli expression system.
| Schlagworte: | SIRT2, SIR2L, SIR2-like protein 2, Regulatory protein SIR2 homolog 2, NAD-dependent protein deacetylase sirtuin-2,... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 35.5 kD |
679,00 €
Salermide
Artikelnummer: Cay13178-10
The sirtuins (SIRTs) are a family of NAD+-dependent histone deacetylases involved in gene regulation that is relevant to, e.g., longevity, cancer, gene regulation, energy homeostasis, and apoptosis. Salermide is an inhibitor of SIRT1 and SIRT2, causing tumor-specific apoptotic cell death. In MOLT4 leukemia cells,...
| Schlagworte: | N-[3-[[(2-hydroxy-1-naphthalenyl)methylene]amino]phenyl]-a-methyl-benzeneacetamide |
| Anwendung: | SIRT inhibitor |
| CAS | 1105698-15-4 |
| MW: | 394.5 D |
ab 68,00 €
AGK2
Artikelnummer: Cay13145-5
Mammalian sirtuin 2 (SIRT2) is a nicotinamide adenine dinucleotide-dependent histone deacetylase (HDAC) with roles in cell cycle progression and tumorigenesis. AGK2 is a cell-permeable, selective inhibitor of SIRT2 (IC50 = 3.5 µM) that minimally affects either SIRT1 or SIRT3 at 10-fold higher levels. It rescues...
| Schlagworte: | 2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide |
| Anwendung: | SIRT2 inhibitor |
| CAS | 304896-28-4 |
| MW: | 434.3 D |
ab 43,00 €