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NAD-dependent protein deacetylase sirtuin-1 (SIRT1), human, recombinant
NAD-dependent protein deacetylase sirtuin-1 (SIRT1),...

Artikelnummer: CSB-EP822202HU.1

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 2-747aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: ADEAALALQP GGSPSAAGAD REAASSPAGE PLRKRPRRDG PGLERSPGEP GGAAPEREVP AAARGCPGAA AAALWREAEA EAAAAGGEQE AQATAAAGEG DNGPGLQGPS REPPLADNLY...
Schlagworte: SIR2L1, Recombinant Human NAD-dependent protein deacetylase sirtuin-1 (SIRT1)
Anwendung: Activity not tested
Exprimiert in: E.coli
Ursprungsart: human
MW: 85.5 kD
ab 213,00 €
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NAD-dependent protein deacetylase sirtuin-1 (SIRT1), human, recombinant
NAD-dependent protein deacetylase sirtuin-1 (SIRT1),...

Artikelnummer: CSB-EP822202HUc7.1

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 2-747aa. Protein Length: Full Length of Mature Protein. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: ADEAALALQP GGSPSAAGAD REAASSPAGE PLRKRPRRDG PGLERSPGEP GGAAPEREVP AAARGCPGAA AAALWREAEA EAAAAGGEQE AQATAAAGEG DNGPGLQGPS REPPLADNLY...
Schlagworte: SIR2L1, Recombinant Human NAD-dependent protein deacetylase sirtuin-1 (SIRT1)
Anwendung: Activity not tested
Exprimiert in: E.coli
Ursprungsart: human
MW: 83.1 kD
ab 213,00 €
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Anti-SIRT1
Anti-SIRT1

Artikelnummer: CSB-PA004095.100

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: Anti-SIR2L1, 75SirT1 antibody, hSIR2 antibody, hSIRT1 antibody, HST2 antibody, HST2, S. cerevisiae, homolog of antibody,...
Anwendung: ELISA, WB, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 106,00 €
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Anti-SIRT1 Recombinant Monoclonal, clone 9E9
Anti-SIRT1 Recombinant Monoclonal, clone 9E9

Artikelnummer: CSB-RA556800A0HU.100

Isotype: Rabbit IgG. Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity-chromatography. Target Name: SIRT1. Antigen Species: Human
Schlagworte: Anti-SIR2L1, NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 3.5.1.-) (Regulatory protein SIR2 homolog 1)...
Anwendung: ELISA, IHC, IF, Recommended dilution: IHC:1:50-1:200, IF
Wirt: Rabbit
Spezies-Reaktivität: human
ab 201,00 €
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Anti-SIRT1
Anti-SIRT1

Artikelnummer: CSB-PA252235.100

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SIRT1. Antigen Species: Human
Schlagworte: Anti-SIR2L1, 75SirT1 antibody, hSIR2 antibody, hSIRT1 antibody, HST2 antibody, HST2, S. cerevisiae, homolog of antibody,...
Anwendung: ELISA, WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 163,00 €
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Sirtuin 1 (SIRT-1) Activity Assay Kit
Sirtuin 1 (SIRT-1) Activity Assay Kit

Artikelnummer: E-BC-F056.48

Detection principle: This kit uses the fluorescence resonance energy transfer (FRET) method for detection. After deacetylation by SIRT-1, the fluorescent substrate generates an activated fluorescent substrate, which can be decomposed by proteases to produce fluorescent substances. The maximum excitation wavelength...
Schlagworte: SIR2L1, Sirtuin 1 (SIRT-1) Activity Assay Kit
ab 376,00 €
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Anti-SIRT1
Anti-SIRT1

Artikelnummer: NSJ-RQ5549

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Sirtuin 1, also known as SIR2L1 or SIRT1, is a protein that in humans is encoded by the SIRT1 gene. It is mapped to 10q21.3. Sirtuin 1 is a member of the sirtuin family of proteins, homologs of the Sir2 gene in S. cerevisiae. Members of the sirtuin family are...
Schlagworte: Anti-SIR2L1, SIRT1 Antibody
Anwendung: WB, IHC (paraffin), IF, FC, Direct ELISA
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
755,00 €
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SIRT1 Direct Fluorescent Screening Assay Kit
SIRT1 Direct Fluorescent Screening Assay Kit

Artikelnummer: Cay10010401-96

Sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs). Human SIRT1 is the homolog of yeast Silent information regulator 2 (Sir2) and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Small molecule activators of SIRT1,...
Schlagworte: SIRT1, hSIR2, hSIRT1, SIR2L1, EC=3.5.1.-, SIR2-like protein 1, NAD-dependent deacetylase sirtuin-1
Anwendung: SIRT1 inhibitor/activator screening
Spezies-Reaktivität: human
467,00 €
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Mouse SIRT1 (Sirtuin 1) ELISA Kit
Mouse SIRT1 (Sirtuin 1) ELISA Kit

Artikelnummer: ELK-ELK6397.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse SIRT1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse SIRT1. Next,...
Schlagworte: Sirt1, Sir2l1
Anwendung: ELISA
Spezies-Reaktivität: mouse
ab 365,00 €
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Human SIRT1 (Sirtuin 1) ELISA Kit
Human SIRT1 (Sirtuin 1) ELISA Kit

Artikelnummer: ELK-ELK3255.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SIRT1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SIRT1. Next,...
Schlagworte: SIR2L1
Anwendung: ELISA
Spezies-Reaktivität: human
ab 365,00 €
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Fluorogenic SIRT1 (Sir2) Assay Kit
Fluorogenic SIRT1 (Sir2) Assay Kit

Artikelnummer: BPS-50081

The Fluorogenic SIRT1 Assay Kit is a complete assay system designed to measure Sirtuin 1 (SIRT1) activity for screening and profiling Applications. It comes in a convenient 96-well format, with all the reagents necessary for 100 fluorescent SIRT1 (Sir2) activity measurements. In addition, the kit includes purified...
Schlagworte: SIR2L1,
Anwendung: Enzyme kinetics, inhibitor screening, HTS
657,00 €
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(±)-EX-527
(±)-EX-527

Artikelnummer: Cay10009798-5

EX-527 is an inhibitor of sirtuin 1 (SIRT1, IC50 = 0.098 µM). It is selective for SIRT1 over SIRT2, and SIRT3 (IC50s = 19.6 and 48.7 µM, respectively) and the cytochrome P450 (CYP) isoforms CYP3A4, CYP2D6, CYP2C9, CYP2C19, and CYP1A2 at 1 µM. EX-527 (50 µM) induces cell cycle arrest at the G1 phase in MCF-7...
Schlagworte: 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
Anwendung: SIRT1 inhibitor
CAS 49843-98-3
MW: 248.7 D
ab 43,00 €
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