Zu "K11411" wurden 146 Artikel gefunden!
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Anti-phospho-SIRT1 (Ser47)
Artikelnummer: CSB-PA857953.100
Protein function: NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metabolism, apoptosis and autophagy (PubMed:11672523,...
| Schlagworte: | Anti-phospho-SIR2L1, Phospho-SIRT1 (Ser47) Antibody |
| Anwendung: | ELISA, WB |
| Spezies-Reaktivität: | human |
320,00 €
NAD-dependent protein deacetylase sirtuin-1 (SIRT1),...
Artikelnummer: CSB-MP822202HU.1
Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 2-747aa. Protein Length: Full Length of Mature Protein. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: ADEAALALQP GGSPSAAGAD REAASSPAGE PLRKRPRRDG PGLERSPGEP GGAAPEREVP AAARGCPGAA AAALWREAEA EAAAAGGEQE AQATAAAGEG DNGPGLQGPS...
| Schlagworte: | SIR2L1 |
| Anwendung: | Activity not tested |
| Exprimiert in: | Mammalian cells |
| Ursprungsart: | human |
| MW: | 83.3 kD |
ab 371,00 €
Anti-SIRT1
Artikelnummer: ABS-KC-924.100
Protein function: NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metabolism, apoptosis and autophagy (PubMed:11672523,...
| Schlagworte: | Anti-NAD-dependent protein deacetylase sirtuin-1, Anti-hSIRT1, Anti-NAD-dependent protein deacylase sirtuin-1,... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 232,00 €
Anti-SIRT1
Artikelnummer: ABS-KC-974.100
Protein function: NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metabolism, apoptosis and autophagy (PubMed:11672523,...
| Schlagworte: | Anti-NAD-dependent protein deacetylase sirtuin-1, Anti-hSIRT1, Anti-NAD-dependent protein deacylase sirtuin-1,... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse |
ab 232,00 €
Anti-SIRT1
Artikelnummer: ABS-KC-6173.100
Protein function: NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metabolism, apoptosis and autophagy (PubMed:11672523,...
| Schlagworte: | Anti-NAD-dependent protein deacetylase sirtuin-1, Anti-hSIRT1, Anti-NAD-dependent protein deacylase sirtuin-1,... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 232,00 €
Inauhzin
Artikelnummer: TGM-T1887-100mg
Description: Inauhzin (INZ)(INZ) is a novel small molecule that effectively reactivates p53 by inhibiting SIRT1 activity, promotes p53-dependent apoptosis of human Y cells without causing apparently genotoxic stress(IC50=3 uM, in A549 cell). Target: Sirtuin. Smiles:...
| Schlagworte: | INZ |
| Anwendung: | Cell-permeable SIRT1 inhibitor |
| CAS | 309271-94-1 |
| MW: | 469.58 D |
ab 37,00 €
Sirtinol
Artikelnummer: TGM-T6671-100mg
Description: Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 µM). Target: Apoptosis, Sirtuin, Autophagy. Smiles: CC(NC(=O)C1=C(C=CC=C1)\N=C\C1=C(O)C=CC2=CC=CC=C12)C1=CC=CC=C1. References: Grozinger CM, et al. J Biol Chem, 2001, 276(42), 38837-38843.
| Anwendung: | Sirtuin-1 inhibitor |
| CAS | 410536-97-9 |
| MW: | 394.47 D |
ab 37,00 €
SRT 2104
Artikelnummer: TGM-T6679-100mg
Description: SRT 2104 (GSK2245840) is a selective and brain-permeable SIRT1 activator. Target: Sirtuin. Smiles: Cc1nc(sc1C(=O)Nc1ccccc1-c1cn2c(CN3CCOCC3)csc2n1)-c1cccnc1. References: Mercken EM, et al. Aging Cell. 2014, 13(5), 787-796.
| Schlagworte: | GSK2245840, sirtuin modulator, SRT2104 |
| Anwendung: | SIRT1 activator |
| CAS | 1093403-33-8 |
| MW: | 516.64 D |
ab 40,00 €
SIRT1 Direct Fluorescent Screening Assay Kit
Artikelnummer: Cay10010401-96
Sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs). Human SIRT1 is the homolog of yeast Silent information regulator 2 (Sir2) and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Small molecule activators of SIRT1,...
| Schlagworte: | SIRT1, hSIR2, hSIRT1, SIR2L1, EC=3.5.1.-, SIR2-like protein 1, NAD-dependent deacetylase sirtuin-1 |
| Anwendung: | SIRT1 inhibitor/activator screening |
| Spezies-Reaktivität: | human |
476,00 €
cis-trismethoxy Resveratrol
Artikelnummer: TGM-T3330L-100mg
Description: cis-trismethoxy Resveratrol ((Z)-3,5,4'-Trimethoxystilbene) inhibits tubulin polymerization (IC50 = 4 µM) and has anti-mitotic effects. Target: Microtubule Associated. Smiles: C(=C\C1=CC=C(OC)C=C1)\C2=CC(OC)=CC(OC)=C2. References: Schneider Y, et al. Resveratrol analog (Z)-3,5,4'-trimethoxystilbene is a...
| Schlagworte: | (Z)-3,5,4'-Trimethoxystilbene |
| Anwendung: | Antiproliferative, antineoplastic, antiangiogenic agent |
| CAS | 94608-23-8 |
| MW: | 270.32 D |
ab 46,00 €
Fisetin
Artikelnummer: TGM-T2879-100mg
Description: Fisetin belongs to a group of natural flavonols with a variety of biological activities, including anti-inflammatory, antioxidant, anti-tumor, anti-aging and neuroprotective effects. Target: PPAR, Sirtuin, TNF. Smiles: OC1=C(OC=2C(C1=O)=CC=C(O)C2)C3=CC(O)=C(O)C=C3. References: Kim SC, et al. Fisetin...
| Anwendung: | Sirtuin 1 activator, antioxidant |
| CAS | 528-48-3 |
| MW: | 286.24 D |
ab 42,00 €
CAY10591
Artikelnummer: TGM-T35812-10mg
Description: Sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs). Human SIRT1 is the homolog of yeast silent information regulator 2 (Sir2) and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Small molecule...
| Schlagworte: | CAY10591 |
| Anwendung: | SIRT1 assays |
| CAS | 839699-72-8 |
| MW: | 367.44 D |
ab 159,00 €