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Zu "K11404" wurden 95 Artikel gefunden!
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Artikelnummer: TGM-T21719-5mg
Description: m-Carboxycinnamic acid bishydroxamide, an effective HDAC inhibitor, shows ID50 values of 10 nM for HDAC1 and 70 nM for HDAC3 in vitro, demonstrating its potent activity. Additionally, it promotes apoptosis and inhibits tumor growth, highlighting its therapeutic potential [1][2]. Target: Others. Smiles:...
Anwendung: | HDAC inhibitor |
CAS | 174664-65-4 |
MW: | 222.2 D |
ab 193,00 €
Artikelnummer: TGM-T36575-10mg
Description: HDAC3 inhibitor is an allosteric inhibitor of histone deacetylase 3 (HDAC3, Ki = 0.16 nM). It is selective for HDAC3 over HDAC1 and HDAC2 (IC50s = 0.95, 11.81, and 95.45 nM, respectively, using recombinant HDACs). In addition, it is selective for acute myeloid, monocytic, and lymphoblastic leukemia cell...
Anwendung: | HDAC3 inhibitor |
CAS | 2044701-99-5 |
MW: | 337.42 D |
ab 120,00 €
Artikelnummer: TGM-T8233-100mg
Description: BRD3308 is a highly selective inhibitor of HDAC3(IC50 of 54 nM), attenuating PE-mediated phosphorylation of ERK but not JNK. Target: Apoptosis, HDAC, HIV Protease. Smiles: CC(=O)Nc1ccc(cc1)C(=O)Nc1ccc(F)cc1N. References: Lundh M, et al. Histone deacetylase 3 inhibition improves glycaemia and insulin...
Anwendung: | HDAC3 inhibitor |
CAS | 1550053-02-5 |
MW: | 287.29 D |
ab 38,00 €
Artikelnummer: TGM-T8517-100mg
Description: Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity. Target: HDAC, Autophagy. Smiles: S(NC1=CC=CC=C1)(=O)(=O)C2=CC(/C=C/C(NO)=O)=CC=C2. References: Plumb J A , Finn P W , Williams R J , et al....
Schlagworte: | PXD101, PX105684, PXD-101 |
Anwendung: | Class I & II HDAC inhibitor |
CAS | 866323-14-0 |
MW: | 318.35 D |
ab 40,00 €
Artikelnummer: TGM-TMPH-01473-100ug
Description: HDAC3 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 64.8 kDa and the accession number is O15379.
Schlagworte: | Protein deacylase HDAC3, Protein deacetylase HDAC3, RPD3-2, Histone deacetylase 3, HDAC3, SMAP45 |
MW: | 64.8 kD |
ab 193,00 €
Artikelnummer: TGM-T1762-100mg
Description: RGFP966 is an HDAC3 inhibitor (IC50: 0.08 µM) and does not affect other HDACs at concentrations up to 15 µM. Target: HDAC. Smiles: Nc1cc(F)ccc1NC(=O)\C=C\c1cnn(C\C=C\c2ccccc2)c1. References: Malvaez M, et al. HDAC3-selective inhibitor enhances extinction of cocaine-seeking behavior in a persistent...
Schlagworte: | RGFP 966 |
Anwendung: | HDAC3 inhibitor |
CAS | 1357389-11-7 |
MW: | 362.4 D |
ab 32,00 €
Artikelnummer: TGM-T13979-50mg
Description: (S)-3-Hydroxybutanoic acid (L-(+)-3-Hydroxybutyric acid) is a normal human metabolite that has been found elevated in geriatric patients remitting from depression. (S)-3-Hydroxybutanoic acid is synthesized in the liver from acetyl-CoA in humans, and can be used as an energy source by the brain when...
Schlagworte: | L-(+)-3-Hydroxybutyric acid, (S)-beta-Hydroxybutanoic acid, L-beta-Hydroxybutyric acid |
Anwendung: | Endogenous HDAC1/3/4 inhibitor |
CAS | 6168-83-8 |
MW: | 104.1 D |
47,00 €
Artikelnummer: CSB-EP010239HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-428aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: MAKTVAYFYD PDVGNFHYGA GHPMKPHRLA LTHSLVLHYG LYKKMIVFKP YQASQHDMCR FHSEDYIDFL QRVSPTNMQG FTKSLNAFNV GDDCPVFPGL FEFCSRYTGA SLQGATQLNN KICDIAINWA...
Schlagworte: | HD3, HDAC3, RPD3-2, SMAP45, EC=3.5.1.98, Histone deacetylase 3, Recombinant Human Histone deacetylase 3 (HDAC3) |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 64.8 kD |
ab 213,00 €
Artikelnummer: CSB-PA002880.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-HD3, Anti-HDAC3, Anti-SMAP45, Anti-RPD3-2, EC=3.5.1.98, Anti-Histone deacetylase 3, HD3 antibody, HDAC 3 antibody,... |
Anwendung: | ELISA, WB, IHC, IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
Artikelnummer: CSB-PA004117.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-HD3, Anti-HDAC3, Anti-SMAP45, Anti-RPD3-2, EC=3.5.1.98, Anti-Histone deacetylase 3, HD3 antibody, HDAC 3 antibody,... |
Anwendung: | ELISA, WB, IHC, IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat, monkey |
ab 106,00 €
Artikelnummer: CSB-RA906662A0HU.100
Isotype: Rabbit IgG. Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity-chromatography. Target Name: HDAC3. Antigen Species: Human
Schlagworte: | Anti-HD3, Anti-HDAC3, Anti-SMAP45, Anti-RPD3-2, EC=3.5.1.98, Anti-Histone deacetylase 3, Histone deacetylase 3 (HD3) (EC... |
Anwendung: | ELISA, WB, IHC, FC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 201,00 €
Artikelnummer: CSB-PA170084.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
Schlagworte: | Anti-phospho-HD3, Anti-phospho-HDAC3, Anti-phospho-SMAP45, Anti-phospho-RPD3-2, EC=3.5.1.98, Anti-phospho-Histone... |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
330,00 €