Zu "K11305" wurden 21 Artikel gefunden!
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KAT6A (MOZ), FLAG-Tag Recombinant
Artikelnummer: BPS-102174-1
Recombinant human KAT6A (K (lysine) acetyltransferase 6A), also known as MOZ, encompassing amino acids 470-820. This construct contains a N-terminal FLAG-tag. The recombinant protein was affinity purified.
| Schlagworte: | MOZ, KAT6A, MYST-3, Zinc finger protein 220, Histone acetyltransferase KAT6A, Monocytic leukemia zinc finger protein, MOZ,... |
| Anwendung: | SDS-PAGE |
| Ursprungsart: | human |
| MW: | 42 kD |
ab 536,00 €
WM-1119
Artikelnummer: TGM-T4679-100mg
Description: WM-1119 is a highly potent, selective KAT6A/B inhibitor. Target: Histone Acetyltransferase. Smiles: Fc1cc(cc(c1)-c1ccccn1)C(=O)NNS(=O)(=O)c1ccccc1F. References: Baell JB et al. Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth. Nature. 2018 Aug,560(7717):253-257.
| Schlagworte: | WM1119 |
| Anwendung: | KAT6A inhibitor |
| CAS | 2055397-28-7 |
| MW: | 389.38 D |
ab 46,00 €
WM-8014
Artikelnummer: TGM-T4362-100mg
Description: WM-8014 (MOZ-IN-3) is an inhibitor of MOZ(IC50=55 nM), a member of histone acetyltransferases. Target: Histone Acetyltransferase. Smiles: Cc1cc(cc(C(=O)NNS(=O)(=O)c2ccccc2)c1F)-c1ccccc1. References: ARYL SULFONOHYDRAZIDES. WO2016198507
| Schlagworte: | MOZ-IN-3 |
| Anwendung: | KAT6A/KAT6B inhibitor |
| CAS | 2055397-18-5 |
| MW: | 384.42 D |
ab 52,00 €
WM-3835
Artikelnummer: TGM-T9102-100mg
Description: WM-3835 is a novel and high-specific small molecule inhibitor of Lysine Acetyltransferase 7 (KAT7, MYST2, HBO1) , able to potently suppressed OS cell proliferation and migration, and leads to apoptosis activation. Target: Histone Methyltransferase, Apoptosis, Histone Acetyltransferase. Smiles:...
| Anwendung: | KAT6A / KAT7 inhibitor |
| CAS | 2229025-70-9 |
| MW: | 400.42 D |
ab 31,00 €
MOZ-IN-2
Artikelnummer: TGM-T12098-100mg
Description: MOZ-IN-2 is an protein MOZ inhibitor(IC50 of 125 µM). Target: Histone Acetyltransferase. Smiles: Fc1ccc(cc1C(=O)NNS(=O)(=O)c1ccccc1)-c1ccnnc1. References: ARYL SULFONOHYDRAZIDES. WO2016198507 A1.
| Anwendung: | KAT6A/MOZ inhibitor |
| CAS | 2055397-88-9 |
| MW: | 372.37 D |
ab 31,00 €
MOZ-IN-2
Artikelnummer: Cay27686-10
MOZ-IN-2 is an inhibitor of lysine acetyltransferase 6A (KAT6A/MOZ, IC50 = 125 µM).Formal Name: 2-(phenylsulfonyl)hydrazide 2-fluoro-5-(4-pyridazinyl)-benzoic acid. CAS Number: 2055397-88-9. Molecular Formula: C17H13FN4O3S. Formula Weight: 372.4. Purity: >98%. Formulation: (Request formulation change), A solid....
| Schlagworte: | 2-(phenylsulfonyl)hydrazide 2-fluoro-5-(4-pyridazinyl)-benzoic acid |
| Anwendung: | KAT6A/MOZ inhibitor |
| CAS | 2055397-88-9 |
| MW: | 372.4 D |
ab 40,00 €
WM-1119
Artikelnummer: Cay30509-5
WM-1119 is an orally bioavailable inhibitor of lysine acetyltransferase 6A (KAT6A/MOZ, IC50 = 6.3 nM). It binds to KAT6A with a Kd value of 2 nM and is selective for KAT6A over KAT5 and KAT7 (Kds = 2,200 and 500 nM, respectively), as well as over a panel of 159 additional targets at 1 and 10 µM. WM-1119 inhibits...
| Schlagworte: | 3-fluoro-5-(2-pyridinyl)-benzoic acid, 2-[(2-fluorophenyl)sulfonyl]hydrazide |
| Anwendung: | KAT6A inhibitor |
| CAS | 2055397-28-7 |
| MW: | 389.4 D |
ab 150,00 €
MOZ-IN-3
Artikelnummer: Cay27402-1
MOZ-IN-3 is an inhibitor of lysine acetyltransferase 6A (KAT6A/MOZ) and KAT6B/MORF (IC50s = 8 and 28 nM, respectively). It is selective for KAT6A and KAT6B over KAT5 and KAT7 (IC50s = 224 and 342 nM, respectively). MOZ-IN-3 induces cell cycle arrest in and inhibits proliferation of mouse embryonic fibroblasts (IC50...
| Schlagworte: | WM-8014, 4-fluoro-5-methyl-[1,1'-biphenyl]-3-carboxylic acid, 2-(phenylsulfonyl)hydrazide |
| Anwendung: | KAT6A/KAT6B inhibitor |
| CAS | 2055397-18-5 |
| MW: | 384.4 D |
ab 52,00 €
Anti-KAT6A
Artikelnummer: ATA-HPA063266.100
Protein function: Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and...
| Schlagworte: | Anti-MOZ, Anti-KAT6A, Anti-MYST-3, Anti-Zinc finger protein 220, Anti-Histone acetyltransferase KAT6A, Anti-Monocytic... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €
Anti-KAT6A
Artikelnummer: ATA-HPA065052.100
Protein function: Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and...
| Schlagworte: | Anti-MOZ, Anti-KAT6A, Anti-MYST-3, Anti-Zinc finger protein 220, Anti-Histone acetyltransferase KAT6A, Anti-Monocytic... |
| Anwendung: | ICC, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €
PF-9363
Artikelnummer: Cay37778-10
PF-9363 is an inhibitor of lysine acetyltransferase 6A (KAT6A), also known as monocytic leukemia zinc finger protein (MOZ) and KAT6B, also known as MOZ-related factor (MORF, Kis = 0.27 and 2.4 nM, respectively). It is selective for KAT6A and KAT6B over KAT7, KAT5, and KAT8 (Kis = 70, 420, and 670 nM, respectively)....
| Schlagworte: | CTx-648, 2,6-dimethoxy-N-[4-methoxy-6-(1H-pyrazol-1-ylmethyl)-1,2-benzisoxazol-3-yl]-benzenesulfonamide |
| Anwendung: | KAT6A / KAT6B inhibitor |
| CAS | 2569009-58-9 |
| MW: | 444.5 D |
ab 55,00 €
WM-3835
Artikelnummer: Cay40296-10
WM-3835 is an inhibitor of lysine acetyltransferase 6A (KAT6A) and KAT7 (IC50s = 17 and 30 nM, respectively). It is selective for KAT6A and KAT7 over KAT5 (IC50 = 312 nM). WM-3835 (1 µM) reduces the viability of primary mouse leukemia stem cells (LSCs), MOLM-13 and OCI-AML-3 acute myeloid lymphoma (AML) cells, as...
| Schlagworte: | 4-fluoro-5-methyl-[1,1'-biphenyl]-3-carboxylic acid, 2-[(3-hydroxyphenyl)sulfonyl]hydrazide |
| Anwendung: | KAT6A / KAT7 inhibitor |
| CAS | 2229025-70-9 |
| MW: | 400.4 D |
ab 108,00 €