Zu "K11262" wurden 79 Artikel gefunden!
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ACC-1, active human recombinant protein
Artikelnummer: BPS-50202
Human ACC1 (acetyl-Coenzyme A carboxylase alpha transcript variant 1) (GenBank Accession No. NM_198834), amino acids 1-2383(end) with C-terminal FLAG and His-tags, MW = 270 kDa, expressed in Baculovirus infected Sf9 cell expression system. A 25 µl ACC1 reaction is conducted in a buffer containing 30 mM HEPES (pH...
| Schlagworte: | ACAC, ACC1, ACC-alpha, Acetyl-CoA carboxylase 1, Acetyl-Coenzyme A carboxylase alpha, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | Baculovirus |
| Ursprungsart: | human |
| MW: | 271 kD |
916,00 €
Acetyl-Coenzyme A Carboxylase 1 (ACC1) Assay Kit
Artikelnummer: BPS-79315
Acetyl-Coenzyme A Carboxylase (ACC) plays an important role in fatty acid metabolism so it has been proposed to be a drug target for the fatty acid-related metabolic diseases including obesity and diabetes. The Acetyl-Coenzyme A Carboxylase 1 (ACC1) assay kit is designed to measure ACC1 activity for screening and...
| Schlagworte: | acetyl-Coenzyme A carboxylase alpha transcript variant 1, ACC-1, ACC 1, ACC -1, acetyl-coa carboxylase, acetyl coa ,... |
| Anwendung: | Enzyme kinetics, drug discovery, HTS |
| Spezies-Reaktivität: | human |
1.409,00 €
PF-05175157
Artikelnummer: TGM-T7163-100mg
Description: PF 05175157 is an inhibitor of acetyl-CoA carboxylase 1 (ACC1) and ACC2 (IC50s = 27, 33, 23.5, and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, respectively. Target: Acetyl-CoA Carboxylase. Smiles: CC(C)n1ncc2CC3(CCN(CC3)C(=O)c3ccc4nc(C)[nH]c4c3)CC(=O)c12. References: Jiménez de Oya,...
| Anwendung: | ACC inhibitor |
| CAS | 1301214-47-0 |
| MW: | 405.49 D |
ab 60,00 €
ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His)
Artikelnummer: TGM-TMPH-03431-100ug
Description: Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which...
| Schlagworte: | Acetyl-CoA carboxylase, mRNA transport-defective protein 7, Fatty acid synthetase 3, ACC |
| MW: | 67.6 kD |
ab 359,00 €
ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His)
Artikelnummer: TGM-TMPH-03432-100ug
Description: Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which...
| Schlagworte: | Acetyl-CoA carboxylase, mRNA transport-defective protein 7, ACC, Fatty acid synthetase 3 |
| MW: | 69.9 kD |
ab 359,00 €
Acetyl-CoA carboxylase Protein, Candida albicans,...
Artikelnummer: TGM-TMPH-00330-100ug
Description: Acetyl-CoA carboxylase Protein, Candida albicans, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 67.3 kDa and the accession number is A0A1D8PRR7.
| Schlagworte: | ACC1 |
| MW: | 67.3 kD |
ab 359,00 €
ND-646
Artikelnummer: TGM-TQ0243-100mg
Description: ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2, with IC50 values of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively. Target: Acetyl-CoA Carboxylase. Smiles: COc1ccccc1[C@H](Cn1c2sc(c(C)c2c(=O)n(c1=O)C(C)(C)C(N)=O)-c1ncco1)OC1CCOCC1. References:...
| Anwendung: | Acetyl-CoA carboxylase inhibitor |
| CAS | 1434639-57-2 |
| MW: | 568.64 D |
ab 77,00 €
CP-640186
Artikelnummer: TGM-T1889-100mg
Description: CP-640186 is an isozyme-nonselective Acetyl-CoA carboxylase (ACCase) inhibitor. The IC50s of CP-640186(CP 640186) is 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. Target: Acetyl-CoA Carboxylase. Smiles: O=C([C@@H]1CCCN(C1)C1CCN(CC1)C(=O)c1c2ccccc2cc2ccccc12)N1CCOCC1....
| Schlagworte: | CP-640,186, CP 640186 |
| Anwendung: | Acetyl-CoA carboxylase / ACC inhibitor |
| CAS | 591778-68-6 |
| MW: | 485.62 D |
ab 33,00 €
Acetyl-CoA carboxylase 1 (Acaca), partial, rat, recombinant
Artikelnummer: CSB-EP001119RA.1
Organism: Rattus norvegicus (Rat). Source: E.coli. Expression Region: 116-617aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: VIEKVLIANN GIAAVKCMRS IRRWSYEMFR NERAIRFVVM VTPEDLKANA EYIKMADHYV PVPGGANNNN YANVELILDI AKRIPVQAVW AGWGHASENP KLPELLLKNG IAFMGPPSQA MWALGDKIAS...
| Schlagworte: | ACC1, Acac, ACC-alpha, Acetyl-CoA carboxylase 1, Recombinant Rat Acetyl-CoA carboxylase 1 (Acaca), partial |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | rat |
| MW: | 59.8 kD |
ab 364,00 €
Acetyl-CoA carboxylase 1 (ACACA), partial, human,...
Artikelnummer: CSB-EP619749HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 78-617aa. Protein Length: Partial. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: SMSGLHLVKQ GRDRKKIDSQ RDFTVASPAE FVTRFGGNKV IEKVLIANNG IAAVKCMRSI RRWSYEMFRN ERAIRFVVMV TPEDLKANAE YIKMADHYVP VPGGPNNNNY ANVELILDIA KRIPVQAVWA GWGHASENPK...
| Schlagworte: | ACAC, ACC1, ACC-alpha, Acetyl-CoA carboxylase 1, Acetyl-Coenzyme A carboxylase alpha, Recombinant Human Acetyl-CoA... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 67.1 kD |
ab 292,00 €
Acetyl-CoA carboxylase (ACC1), partial, Saccharomyces...
Artikelnummer: CSB-EP2725SVG1.1
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). Source: E.coli. Expression Region: 217-775aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: TGLVSVDDDI YQKGCCTSPE DGLQKAKRIG FPVMIKASEG GGGKGIRQVE REEDFIALYH QAANEIPGSP IFIMKLAGRA RHLEVQLLAD...
| Schlagworte: | ACC, ABP2, ACC1, N3175, YNR016C, EC=6.3.4.14, Biotin carboxylase, Acetyl-CoA carboxylase, Fatty acid synthetase 3, mRNA... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | Saccharomyces cerevisiae |
| MW: | 67.6 kD |
ab 364,00 €
Acetyl-CoA carboxylase (ACC1), partial, Saccharomyces...
Artikelnummer: CSB-EP2725SVG2.1
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). Source: E.coli. Expression Region: 2-581aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: SEESLFESSP QKMEYEITNY SERHTELPGH FIGLNTVDKL EESPLRDFVK SHGGHTVISK ILIANNGIAA VKEIRSVRKW AYETFGDDRT...
| Schlagworte: | ACC, ABP2, ACC1, N3175, YNR016C, EC=6.3.4.14, Biotin carboxylase, Acetyl-CoA carboxylase, Fatty acid synthetase 3, mRNA... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | Saccharomyces cerevisiae |
| MW: | 69.9 kD |
ab 364,00 €