Zu "K11204" wurden 33 Artikel gefunden!
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L-Buthionine-(S,R)-Sulfoximine
Artikelnummer: Cay14484-250
L-Buthionine-(S,R)-sulfoximine is an irreversible inhibitor of gamma-glutamylcysteine synthetase (Ki = 25 µM). It inhibits the proliferation of ZAZ and M14 melanoma cells, as well as A2780 ovarian and MCF-7 breast cancer cells (IC50s = 4.9, 18, 8.5, and 26.5 µM, respectively). L-Buthionine-(S,R)-sulfoximine (100µM)...
| Schlagworte: | BSO, NSC 326231, 2S-amino-4-(S-butylsulfonimidoyl)-butanoic acid |
| Anwendung: | Oxidative stress inducer |
| CAS | 83730-53-4 |
| MW: | 222.3 D |
ab 109,00 €
L-BUTHIONINE-(S,R)-SULFOXIMINE
Artikelnummer: TGM-T5371-100mg
Description: L-Buthionine-(S,R)-sulfoximine, a cell-permeable and irreversible inhibitor of gamma-glutamylcysteine synthetase (Ki <100 µM), induces oxidative stress in cells by depleting GSH. Target: Ferroptosis, Others. Smiles: CCCCS(=N)(=O)CC[C@H](N)C(O)=O. References: Marengo B, et al. Mechanisms of BSO...
| Schlagworte: | L-Butionine sulfoximine |
| Anwendung: | Oxidative stress inducer |
| CAS | 83730-53-4 |
| MW: | 222.31 D |
ab 33,00 €
DL-Buthionine-(S,R)-sulfoximine
Artikelnummer: TGM-T7708-25mg
Description: DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of gamma-glutamylcysteine synthetase used for the treatment of solid tumors. Target: Ferroptosis, Others. Smiles: CCCCS(=N)(=O)CCC(N)C(O)=O. References: Arrick, B. A . Inhibition of glutathione synthesis as a chemotherapeutic...
| Schlagworte: | Butionine sulfoximine, NSC 381100, D,L-Buthionine-(S,R)-sulfoximine |
| Anwendung: | gamma-glutamylcysteine synthetase inhibitor |
| CAS | 5072-26-4 |
| MW: | 222.31 D |
ab 31,00 €
Anti-GCLC
Artikelnummer: CSB-PA002665.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-GLCL, Anti-GCLC, Anti-Gamma-ECS, EC=6.3.2.2, Anti-GCS heavy chain, Anti-Gamma-glutamylcysteine synthetase,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
Mouse GCLC (Glutamate Cysteine Ligase, Catalytic) ELISA Kit
Artikelnummer: ELK-ELK6361.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse GCLC. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse GCLC. Next,...
| Schlagworte: | Glclc, Gamma-ECS, GCS heavy chain, Gamma-glutamylcysteine synthetase, Glutamate--cysteine ligase catalytic subunit |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Rat GCLC (Glutamate Cysteine Ligase, Catalytic) ELISA Kit
Artikelnummer: ELK-ELK6793.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat GCLC. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat GCLC. Next,...
| Schlagworte: | Glclc, Gamma-ECS, GCS heavy chain, Gamma-glutamylcysteine synthetase, Glutamate--cysteine ligase catalytic subunit |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
Human GCLC (Glutamate Cysteine Ligase, Catalytic) ELISA Kit
Artikelnummer: ELK-ELK8717.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human GCLC. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human GCLC. Next,...
| Schlagworte: | GLCL, Gamma-ECS, GCS heavy chain, Gamma-glutamylcysteine synthetase, Glutamate--cysteine ligase catalytic subunit |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
D,L-Buthionine-(S,R)-Sulfoximine
Artikelnummer: Cay23691-250
D,L-Buthionine-(S,R)-sulfoximine is an inhibitor of gamma-glutamylcysteine synthetase that induces 100% inhibition at a concentration of 10 µM in an enzyme assay. It is selective for gamma-glutamylcysteine synthetase, lacking activity at glutamine synthetase at concentrations up to 500 µM....
| Schlagworte: | NSC 381100, 2-amino-4-(S-butylsulfonimidoyl)-butanoic acid |
| Anwendung: | gamma-glutamylcysteine synthetase inhibitor |
| CAS | 5072-26-4 |
| MW: | 222.3 D |
ab 92,00 €
Human GCLC ELISA Kit
Artikelnummer: G-HUFI01282.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Anti-GCLC
Artikelnummer: NSJ-R30565
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Glutamate--cysteine ligase catalytic subunit, is an enzyme that in humans is encoded by the GCLC gene. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of...
| Schlagworte: | Anti-GCLC, Anti-GLCL, Anti-Gamma-ECS, EC=6.3.2.2, Anti-GCS heavy chain, Anti-Gamma-glutamylcysteine synthetase,... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Anti-GCLC
Artikelnummer: NSJ-R31614
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Glutamate-cysteine ligase catalytic subunit is an enzyme that in humans is encoded by the GCLC gene. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two...
| Schlagworte: | Anti-GLCL, Anti-GCLC, Anti-Gamma-ECS, EC=6.3.2.2, Anti-GCS heavy chain, Anti-Gamma-glutamylcysteine synthetase,... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
755,00 €
Anti-GCLC
Artikelnummer: NSJ-F41799-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit,...
| Schlagworte: | Anti-GCLC, Anti-GLCL, Anti-Gamma-ECS, EC=6.3.2.2, Anti-GCS heavy chain, Anti-Gamma-glutamylcysteine synthetase,... |
| Anwendung: | WB, IHC, IF, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 326,00 €