Zu "K11126" wurden 94 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Anti-Telomerase (hTERT Catalytic Unit)
Artikelnummer: 600-401-252
Protein function: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the...
| Schlagworte: | Anti-TP2, Anti-TERT, Anti-EST2, Anti-HEST2, EC=2.7.7.49, Anti-Telomerase catalytic subunit, Anti-Telomerase-associated... |
| Anwendung: | ELISA, IHC, IFM, IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 180,00 €
TMPyP4 tosylate
Artikelnummer: TGM-T13174-100mg
Description: TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and telomerase inhibitor that exhibits antitumor effects in osteosarcoma cell lines. Target: DNA/RNA Synthesis, Telomerase. Smiles:...
| Schlagworte: | TMP 1363 |
| Anwendung: | G-quadruplex stabilizer, telomerase inhibitor |
| CAS | 36951-72-1 |
| MW: | 1363.6 D |
ab 34,00 €
Cyclogalegenin
Artikelnummer: TGM-T3333-100mg
Description: Cyclogalegenin (Astramembrangenin) is able to elongate telomeres, resulting in increased lifespan of the animals. Target: Telomerase. Smiles: C[C@]12[C@]3([C@]4([C@]5(C4)[C@@]([C@@H](O)C3)(C(C)(C)[C@@H](O)CC5)[H])CC[C@]1(C)[C@]([C@@H](O)C2)([C@@]6(C)O[C@@H]([C@@](C)(C)O)CC6)[H])[H]. References: de Jesus...
| Schlagworte: | Cyclogalegigenin, Astramembrangenin, Cyclogalagenin, Cycloastragenol |
| Anwendung: | Reported telomerase activator |
| CAS | 84605-18-5 |
| MW: | 490.71 D |
ab 31,00 €
Costunolide
Artikelnummer: TGM-T2902-100mg
Description: Costunolide (Costus lactone) has anti-inflammatory and anti-oxidant properties and mediates apoptosis. Target: Endogenous Metabolite, Apoptosis, Telomerase. Smiles: [H][C@]12OC(=O)C(=C)[C@]1([H])CC\C(C)=C\CC\C(C)=C\2. References: Choi SH, et al, Cancer Lett, 2005, 227(2), 153-162.
| Schlagworte: | Costunolid, (+)-Costunolide, Costus lactone, NSC 106404 |
| Anwendung: | Apoptosis inducer |
| CAS | 553-21-9 |
| MW: | 232.32 D |
ab 51,00 €
beta-Rubromycin
Artikelnummer: TGM-T35428-1mg
Description: beta-Rubromycin is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities.1 It inhibits the growth of HMO2, KATO-III, and MCF-7 cells with GI50 values of 0.5, 0.84, and <0.1 µM, respectively. beta-rubromycin inhibits HIV-1 reverse transcriptase activity by...
| Anwendung: | Human telomerase inhibitor, HIV-1 reverse transcriptase inhibitor |
| CAS | 27267-70-5 |
| MW: | 536.445 D |
ab 214,00 €
MST-312
Artikelnummer: TGM-T41290-10mg
Description: MST-312 (Telomerase Inhibitor IX) is a derivative of green tea epigallocatechin gallate (EGCG). MST-312 is a telomerase inhibitor. MST-312 has research value in cancer, such as multiple myeloma (MM). Target: Telomerase. Smiles: Oc1cccc(C(=O)Nc2cccc(NC(=O)c3cccc(O)c3O)c2)c1O. References: Ameri Z, et al....
| Schlagworte: | Telomerase Inhibitor IX |
| Anwendung: | Telomerase inhibitor |
| CAS | 368449-04-1 |
| MW: | 380.35 D |
ab 32,00 €
RHPS4
Artikelnummer: TGM-T6967-100mg
Description: RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar. Target: Apoptosis, Telomerase. Smiles: COS([O-])(=O)=O.Cc1cc2n(C)c3ccc(F)cc3c3[n+](C)c4ccc(F)cc4c(c1)c23. References: Phatak P, et al. Br J Cancer. 2007, 96(8):1223-33.
| Schlagworte: | RHPS 4 methosulfate, NSC714187 |
| Anwendung: | Telomerase inhibitor |
| CAS | 390362-78-4 |
| MW: | 458.48 D |
ab 40,00 €
TERT Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-02186-100ug
Description: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the...
| Schlagworte: | HEST2, Telomerase-associated protein 2, Telomerase catalytic subunit, TERT, Telomerase reverse transcriptase |
| MW: | 22.7 kD |
ab 237,00 €
TRET Protein, Mouse, Recombinant (His & SUMO)
Artikelnummer: TGM-TMPH-02926-100ug
Description: TRET Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 54.1 kDa and the accession number is O70372.
| Schlagworte: | Tert, Telomerase reverse transcriptase, Telomerase catalytic subunit |
| MW: | 54.1 kD |
ab 359,00 €
6-Thio-2'-Deoxyguanosine
Artikelnummer: TGM-T6746-100mg
Description: 6-Thio-2'-Deoxyguanosine (beta-TGdR) is a nucleoside analog and telomerase substrate. Target: DNA/RNA Synthesis, Others. Smiles: Nc1nc(=S)c2ncn([C@H]3C[C@H](O)[C@@H](CO)O3)c2[nH]1. References: Mender I, et al. Cancer Discov. 2015, 5(1), 82-95.
| Schlagworte: | beta-TGdR, 6-Thio-dG |
| Anwendung: | Nucleoside analog, telomeric DNA damage inducer |
| CAS | 789-61-7 |
| MW: | 283.31 D |
ab 51,00 €
Telomerase reverse transcriptase (TERT), partial, human,...
Artikelnummer: CSB-EP023391HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 281-436aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: EATSLEGALS GTRHSHPSVG RQHHAGPPST SRPPRPWDTP CPPVYAETKH FLYSSGDKEQ LRPSFLLSSL RPSLTGARRL VETIFLGSRP WMPGTPRRLP RLPQRYWQMR PLFLELLGNH AQCPYGVLLK THCPLRAAVT...
| Schlagworte: | TP2, EST2, TERT, HEST2, Telomerase catalytic subunit, Telomerase-associated protein 2, Telomerase reverse transcriptase,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 22.7 kD |
ab 244,00 €
Telomerase reverse transcriptase (Tert), partial, mouse,...
Artikelnummer: CSB-EP023391MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 595-928aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: EVRHHQDTWL AMPICRLRFI PKPNGLRPIV NMSYSMGTRA LGRRKQAQHF TQRLKTLFSM LNYERTKHPH LMGSSVLGMN DIYRTWRAFV LRVRALDQTP RMYFVKADVT GAYDAIPQGK LVEVVANMIR...
| Schlagworte: | Tert, EC=2.7.7.49, Telomerase catalytic subunit, Telomerase reverse transcriptase, Recombinant Mouse Telomerase reverse... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 54.1 kD |
ab 360,00 €