Zu "K10799" wurden 65 Artikel gefunden!
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![Poly [ADP-ribose] polymerase tankyrase-1 (TNKS), Partial, human, recombinant](https://www.biomol.com/media/image/85/fa/d5/CSB-EP024004HU-1_200x200.jpg "Poly [ADP-ribose] polymerase tankyrase-1 (TNKS), Partial, human, recombinant")
Poly [ADP-ribose] polymerase tankyrase-1 (TNKS), Partial,...
Artikelnummer: CSB-EP024004HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 181-964aa. Protein Length: Partial. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: GALRELLEAC RNGDVSRVKR LVDAANVNAK DMAGRKSSPL HFAAGFGRKD VVEHLLQMGA NVHARDDGGL IPLHNACSFG HAEVVSLLLC QGADPNARDN WNYTPLHEAA IKGKIDVCIV LLQHGADPNI RNTDGKSALD...
| Schlagworte: | ARTD5, TANK1, TNKS-1, Tankyrase I, Tankyrase-1, Poly [ADP-ribose] polymerase 5A, Poly [ADP-ribose] polymerase tankyrase-1,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 91.9 kD |
ab 283,00 €
![Poly [ADP-ribose] polymerase tankyrase-2 (TNKS2), partial, human, recombinant](https://www.biomol.com/media/image/03/b1/e3/CSB-EP867136HUa0-1_200x200.jpg "Poly [ADP-ribose] polymerase tankyrase-2 (TNKS2), partial, human, recombinant")
Poly [ADP-ribose] polymerase tankyrase-2 (TNKS2),...
Artikelnummer: CSB-EP867136HUa0.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 57-776aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: RKSTPLHFAA GFGRKDVVEY LLQNGANVQA RDDGGLIPLH NACSFGHAEV VNLLLRHGAD PNARDNWNYT PLHEAAIKGK IDVCIVLLQH GAEPTIRNTD GRTALDLADP SAKAVLTGEY KKDELLESAR SGNEEKMMAL...
| Schlagworte: | TANK2, ARTD6, TNKS-2, Tankyrase-2, Tankyrase II, Tankyrase-like protein, Tankyrase-related protein, Poly [ADP-ribose]... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 82.6 kD |
ab 283,00 €
Human TNKS1 (Tankyrase 1) ELISA Kit
Artikelnummer: ELK-ELK3071.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TNKS1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TNKS1. Next,...
| Schlagworte: | TANK1, ARTD5, TNKS-1, Tankyrase-1, Tankyrase I, Poly [ADP-ribose] polymerase 5A, Poly [ADP-ribose] polymerase tankyrase-1,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
XAV939
Artikelnummer: Cay13596-1
The Wnt signaling pathway is integral to normal biological processes and inappropriately active in many cancers. It is regulated through degradation of the downstream effector beta-catenin via a complex consisting of the tumor suppressor APC, axin, and glycogen synthase kinase 3 (GSK3). Axin is the...
| Schlagworte: | 3,5,7,8-tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Anwendung: | TNKS inhibitor |
| CAS | 284028-89-3 |
| MW: | 312.3 D |
ab 20,00 €
Anti-Tankyrase 1
Artikelnummer: A302-398A
Protein function: Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction...
| Schlagworte: | Anti-TNKS, Anti-ARTD5, Anti-TANK1, Anti-TNKS-1, Anti-PARP5A, EC=2.4.2.30, Anti-Tankyrase-1, Anti-Tankyrase I, Anti-Poly... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
PJ-34 (hydrochloride)
Artikelnummer: Cay14440-5
The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. PJ-34 is an inhibitor of PARPs which can be used in cells or in animals. It binds and inhibits the PARP tankyrase1 (IC50 = 1 µM). PJ-34 also...
| Schlagworte: | N-(5,6-dihydro-6-oxo-2-phenanthridinyl)-2-(dimethylamino)-acetamide, monohydrochloride |
| Anwendung: | PARP inhibitor |
| CAS | 344458-15-7 |
| MW: | 331.8 D |
ab 50,00 €
Anti-Tankyrase 1
Artikelnummer: A302-399A-T
Protein function: Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction...
| Schlagworte: | Anti-TNKS, Anti-ARTD5, Anti-TANK1, Anti-TNKS-1, Anti-PARP5A, EC=2.4.2.30, Anti-Tankyrase-1, Anti-Tankyrase I, Anti-Poly... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Tankyrase 1 (PARP5A), active human recombinant protein,...
Artikelnummer: BPS-80504
TNKS1 (TRF1-interacting ankyrin-related ADP-ribose polymerase 1), also known as PARP5A, TANK1, or tanykyrase-1 (GenBank Accession No. NM_003747), a.a. 1000-1328(end), with N-terminal GST-tag, MW=62.5 kDa, expressed in Sf9 cells via a baculovirus expression system. Autoribosylation reaction is conducted in wells...
| Schlagworte: | ARTD5, TANK1, TNKS-1, Tankyrase-1, Tankyrase I, Poly [ADP-ribose] polymerase 5A, Poly [ADP-ribose] polymerase tankyrase-1,... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | Baculovirus |
| Ursprungsart: | human |
| MW: | 62.5 kD |
759,00 €
Tankyrase 2 (PARP5b) Active Human Recombinant Protein
Artikelnummer: BPS-80505
TNKS2 (TRF1-interacting ankyrin-related ADP-ribose polymerase 2), also known as PARP5B/C, tanykyrase-2, or TNKL (GenBank Accession No. NM_025235), a.a. 667-1166(end), with N-terminal GST-tag, MW=80.5 kDa, expressed in Sf9 cells via a baculovirus expressio
| Schlagworte: | TANK2, ARTD6, TNKS-2, Tankyrase-2, Tankyrase II, Tankyrase-like protein, Tankyrase-related protein, Poly [ADP-ribose]... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 80.5 kD |
759,00 €
XAV-939
Artikelnummer: LKT-X0384.5
Tankyrase inhibitor.
| Schlagworte: | 2-[4-(trifluoromethyl)phenyl]-7,8-dihydro-5H-thiino[4,3-d]pyrimidin-4-ol |
| Anwendung: | Tankyrase inhibitor |
| CAS | 284028-89-3 |
| MW: | 312.31 D |
ab 94,00 €
G007-LK
Artikelnummer: Cay22934-1
G007-LK is an inhibitor of the tankyrases TNKS1 and TNKS2 (IC50s = 46 and 25 nM, respectively). It is selective for TNKS1 and TNKS2 over a panel of 90 kinases, 16 phosphatases, and 73 G protein-coupled receptors (GPCRs) when used at a concentration of 10 µM. G007-LK inhibits colony formation of COLO 320 DM and SW403...
| Schlagworte: | Tankyrase 1/2 Inhibitor VI,... |
| Anwendung: | TNKS / TNKS2 inhibitor |
| CAS | 1380672-07-0 |
| MW: | 530 D |
ab 43,00 €
JW 55
Artikelnummer: Cay16260-5
JW 55 is an inhibitor of the PARP domain of tankyrases (TNKS) 1 and 2 (IC50s = 1.9 and 0.83 µM, respectively). By inhibiting TNKS1/2, JW 55 stabilizes Axin2 and increases degradation of beta-catenin, inhibiting the beta-catenin signaling pathway (IC50 = 470 nM). It has been shown to decrease canonical Wnt signaling...
| Schlagworte: | Tankyrase 1/2 Inhibitor IV,... |
| Anwendung: | Wnt/beta-catenin signaling inhibitor, Tankyrase inhibitor |
| CAS | 664993-53-7 |
| MW: | 434.5 D |
ab 92,00 €