Zu "K10799" wurden 85 Artikel gefunden!
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![Poly [ADP-ribose] polymerase tankyrase-2 (TNKS2), partial, recombinant human](https://www.biomol.com/media/image/a7/59/08/CSB-EP867136HU1-1_200x200.jpg "Poly [ADP-ribose] polymerase tankyrase-2 (TNKS2), partial, recombinant human")
Poly [ADP-ribose] polymerase tankyrase-2 (TNKS2),...
Artikelnummer: CSB-EP867136HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 873-1161aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: GVDFSITQFV RNLGLEHLMD IFEREQITLD VLVEMGHKEL KEIGINAYGH RHKLIKGVER LISGQQGLNP YLTLNTSGSG TILIDLSPDD KEFQSVEEEM QSTVREHRDG GHAGGIFNRY NILKIQKVCN...
| Schlagworte: | TANK2, ARTD6, TNKS-2, Tankyrase-2, Tankyrase II, Tankyrase-like protein, Tankyrase-related protein, Poly [ADP-ribose]... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 45.8 kD |
ab 292,00 €
NVP-TNKS656
Artikelnummer: TGM-T3261-100mg
Description: NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor. Target: PARP, Apoptosis, Wnt/beta-catenin. Smiles: COc1ccc(cc1)C(=O)C1CCN(CC(=O)N(CC2CC2)Cc2nc3CCOCc3c(=O)[nH]2)CC1. References: Shultz MD, et al. J Med Chem. 2013, 56(16), 6495-6511.
| Schlagworte: | TNKS656 |
| Anwendung: | Tankyrase inhibitor |
| CAS | 1419949-20-4 |
| MW: | 494.58 D |
ab 40,00 €
WIKI4
Artikelnummer: TGM-T3062-100mg
Description: WIKI4 is a potent inhibitor of Wnt/beta-catenin signaling and tankyrase 2 (TNKS2). Target: PARP, Wnt/beta-catenin. Smiles: COc1ccc(cc1)-n1c(SCCCN2C(=O)c3cccc4cccc(C2=O)c34)nnc1-c1ccncc1. References: James RG, et al. PLoS One. 2012, 7(12), e50457.
| Anwendung: | Tankyrase inhibitor |
| CAS | 838818-26-1 |
| MW: | 521.59 D |
ab 34,00 €
G007-LK
Artikelnummer: TGM-T6842-100mg
Description: G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively. Target: PARP, Wnt/beta-catenin. Smiles: CS(=O)(=O)c1ccc(nc1)-c1nnc(\C=C\c2nnc(o2)-c2ccc(cc2)C#N)n1-c1ccccc1Cl. References: Voronkov A, et al. J Med Chem, 2013, 56(7), 32012-3023.
| Anwendung: | TNKS / TNKS2 inhibitor |
| CAS | 1380672-07-0 |
| MW: | 529.96 D |
ab 45,00 €
3,4-Dihydroxyflavone
Artikelnummer: TGM-T8245-1mL
Description: 3,4-Dihydroxyflavone Acts as an Antioxidant and Antiapoptotic Agent . Target: Others. Smiles: Oc1ccc(cc1O)-c1cc(=O)c2ccccc2o1. References: Lee K S , Kim E Y , Jeon K , et al. 3,4-Dihydroxyflavone Acts as an Antioxidant and Antiapoptotic Agent to Support Bovine Embryo Development In Vitro[J]. Journal of...
| Anwendung: | Bioactive synthetic flavonoid, tankyrase inhibitor |
| CAS | 4143-64-0 |
| MW: | 254.24 D |
ab 48,00 €
G244-LM
Artikelnummer: TGM-T8964-10mg
Description: G244-LM, a potent and specific inhibitor of tankyrase 1/2, effectively inhibits Wnt signaling. Target: Others, PARP. Smiles: CS(=O)(=O)c1ccccc1N1CCN(CC1)c1nc2CCSCc2c(=O)[nH]1. References: Lau T , Chan E , Callow M , et al. A Novel Tankyrase Small-Molecule Inhibitor Suppresses APC Mutation-Driven...
| Anwendung: | Tankyrase 1/2 inhibitor |
| CAS | 1563007-08-8 |
| MW: | 406.52 D |
ab 45,00 €
XAV-939
Artikelnummer: TGM-T1878-100mg
Description: XAV-939 (NVP-XAV939) is a Tankyrase (TNKS) inhibitor that inhibits TNKS1 and TNKS2 (IC50=11/4 nM). XAV-939 selectively inhibits Wnt/beta-catenin-mediated transcription. Target: PARP, Wnt/beta-catenin. Smiles: FC(F)(F)C1=CC=C(C=C1)C1=NC(=O)C2=C(CCSC2)N1. References: Huang SM, et al. Tankyrase inhibition...
| Schlagworte: | NVP-XAV939, XAV939 |
| Anwendung: | TNKS inhibitor |
| CAS | 284028-89-3 |
| MW: | 312.31 D |
ab 48,00 €
AZ6102
Artikelnummer: TGM-T6768-100mg
Description: AZ6102 is a potent TNKS1/2 inhibitor that has 100-fold selectivity against other PARP family enzymes and shows IC50 of 5 nM for Wnt pathway inhibition in DLD-1 cells. Target: PARP, Wnt/beta-catenin. Smiles: C[C@H]1CN(C[C@@H](C)N1)c1cc(C)c(cn1)-c1ccc(cc1)-c1nc2n(C)ccc2c(=O)[nH]1. References: Johannes...
| Anwendung: | TNKS1/2 inhibitor |
| CAS | 1645286-75-4 |
| MW: | 428.53 D |
ab 38,00 €
Tankyrase-IN-2
Artikelnummer: TGM-T13078-100mg
Description: Tankyrase-IN-2 is a selective, potent and orally active inhibitor of tankyrase with IC50s of 10, 7, and 710 nM for TNKS1, TNKS2 as well as PARP1, respectively. Target: Wnt/beta-catenin. Smiles: CC(C)(O)c1ccc(cc1)-c1nc2c(F)cc(F)cc2c(=O)[nH]1. References: Buchstaller HP, et al. Discovery and Optimization...
| Anwendung: | TNKS1 / TNKS2 inhibitor |
| CAS | 1588870-36-3 |
| MW: | 316.3 D |
ab 1.400,00 €
RK-287107
Artikelnummer: TGM-T16761-100mg
Description: RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively). Target: Others, PARP. Smiles: OCCN1CC2(CCN(CC2)c2nc3CCCCc3c(=O)[nH]2)c2c1cc(F)cc2F. References: Mizutani A, et al. RK-287107, a potent and specific tankyrase inhibitor,...
| Anwendung: | TNKS1/2 inhibitor |
| CAS | 2171386-10-8 |
| MW: | 416.46 D |
ab 34,00 €
![Poly [ADP-ribose] polymerase tankyrase-1 (TNKS), Partial, human, recombinant](https://www.biomol.com/media/image/85/fa/d5/CSB-EP024004HU-1_200x200.jpg "Poly [ADP-ribose] polymerase tankyrase-1 (TNKS), Partial, human, recombinant")
Poly [ADP-ribose] polymerase tankyrase-1 (TNKS), Partial,...
Artikelnummer: CSB-EP024004HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 181-964aa. Protein Length: Partial. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: GALRELLEAC RNGDVSRVKR LVDAANVNAK DMAGRKSSPL HFAAGFGRKD VVEHLLQMGA NVHARDDGGL IPLHNACSFG HAEVVSLLLC QGADPNARDN WNYTPLHEAA IKGKIDVCIV LLQHGADPNI RNTDGKSALD...
| Schlagworte: | ARTD5, TANK1, TNKS-1, Tankyrase I, Tankyrase-1, Poly [ADP-ribose] polymerase 5A, Poly [ADP-ribose] polymerase tankyrase-1,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 91.9 kD |
ab 292,00 €
![Poly [ADP-ribose] polymerase tankyrase-2 (TNKS2), partial, human, recombinant](https://www.biomol.com/media/image/03/b1/e3/CSB-EP867136HUa0-1_200x200.jpg "Poly [ADP-ribose] polymerase tankyrase-2 (TNKS2), partial, human, recombinant")
Poly [ADP-ribose] polymerase tankyrase-2 (TNKS2),...
Artikelnummer: CSB-EP867136HUa0.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 57-776aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: RKSTPLHFAA GFGRKDVVEY LLQNGANVQA RDDGGLIPLH NACSFGHAEV VNLLLRHGAD PNARDNWNYT PLHEAAIKGK IDVCIVLLQH GAEPTIRNTD GRTALDLADP SAKAVLTGEY KKDELLESAR SGNEEKMMAL...
| Schlagworte: | TANK2, ARTD6, TNKS-2, Tankyrase-2, Tankyrase II, Tankyrase-like protein, Tankyrase-related protein, Poly [ADP-ribose]... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 82.6 kD |
ab 292,00 €