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Zu "K10771" wurden 78 Artikel gefunden!
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Artikelnummer: ABS-KC-1200.100
Protein function: Multifunctional protein that plays a central role in the cellular response to oxidative stress. The two major activities of APEX1 are DNA repair and redox regulation of transcriptional factors. Functions as a apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER)...
Schlagworte: | Anti-DNA-(apurinic or apyrimidinic site) endonuclease, Anti-APEX nuclease, Anti-APEN, Anti-Apurinic-apyrimidinic... |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
ab 232,00 €
Artikelnummer: TGM-T6823-100mg
Description: E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity. Target: DNA/RNA Synthesis, HIF/HIF Prolyl-Hydroxylase. Smiles: CCCCCCCCC\C(=C/C1=C(C)C(=O)C(OC)=C(OC)C1=O)C(O)=O. References: Zou GM, et al. Blood. 2007, 109(5), 1917-1922.
Anwendung: | APE1/Ref-1 redox inhibitor |
CAS | 136164-66-4 |
MW: | 378.46 D |
ab 46,00 €
Artikelnummer: TGM-TMPY-02433-100ug
Description: The enzyme is known to be a redox factor (Ref-1) stimulating DNA binding activity of AP-1 binding proteins such as Fos and Jun as well as a multifunctional DNA repair enzyme having 5' AP endonuclease, DNA 3' repair diesterase, 3'-5' exonuclease and DNA 3'-phosphatase activities.Although Apex mRNA was...
Schlagworte: | APEX nuclease (multifunctional DNA repair enzyme) 1, APE, APEN, REF1, APE1, APEX, HAP1, APX |
MW: | 37 kD |
699,00 €
Artikelnummer: TGM-T6456-100mg
Description: CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 µM. Target: DNA/RNA Synthesis. Smiles: OC(=O)c1cc2cccc([N+]([O-])=O)c2[nH]1. References: Madhusudan S, et al. Nucleic Acids Res. 2005, 33(15), 4711-4724.
Schlagworte: | 7-Nitroindole-2-Carboxylic Acid, NSC 69877, NSC 69877,7-NO2-ICA |
Anwendung: | Cell-permeable Ape-1 inhibitor |
CAS | 6960-45-8 |
MW: | 206.15 D |
ab 31,00 €
Artikelnummer: CSB-EP001900HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 32-318aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: KNDKEAAGEG PALYEDPPDQ KTSPSGKPAT LKICSWNVDG LRAWIKKKGL DWVKEEAPDI LCLQETKCSE NKLPAELQEL PGLSHQYWSA PSDKEGYSGV GLLSRQCPLK VSYGIGDEEH...
Schlagworte: | APE, APEX1, Recombinant Human DNA- (apurinic or apyrimidinic site) lyase (APEX1) |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 36.2 kD |
ab 219,00 €
Artikelnummer: CSB-YP001900HU.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 32-318aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: KNDKEAAGEG PALYEDPPDQ KTSPSGKPAT LKICSWNVDG LRAWIKKKGL DWVKEEAPDI LCLQETKCSE NKLPAELQEL PGLSHQYWSA PSDKEGYSGV GLLSRQCPLK VSYGIGDEEH...
Schlagworte: | APE, APEX1, Recombinant Human DNA- (apurinic or apyrimidinic site) lyase (APEX1) |
Anwendung: | Activity not tested |
Exprimiert in: | Yeast |
Ursprungsart: | human |
MW: | 34.2 kD |
ab 347,00 €
Artikelnummer: CSB-PA003956.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-APE, Anti-APEX1, AP endonuclease 1 antibody, AP endonuclease class I antibody, AP lyase antibody, APE 1 antibody, APE... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Artikelnummer: CSB-PA005467.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-APE, Anti-APEX1, AP endonuclease 1 antibody, AP endonuclease class I antibody, AP lyase antibody, APE 1 antibody, APE... |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 126,00 €
Artikelnummer: CSB-PA000108.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-acetyl-APE, Anti-acetyl-APEX1, AP endonuclease 1 antibody, AP endonuclease class I antibody, AP lyase antibody, APE 1... |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 126,00 €
Artikelnummer: CSB-PA000109.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-acetyl-APE, Anti-acetyl-APEX1, AP endonuclease 1 antibody, AP endonuclease class I antibody, AP lyase antibody, APE 1... |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 126,00 €
Artikelnummer: CSB-PA234773.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
Schlagworte: | Anti-APE, Anti-APEX1, AP endonuclease 1 antibody, AP endonuclease class I antibody, AP lyase antibody, APE 1 antibody, APE... |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
283,00 €
Artikelnummer: CSB-PA242845.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: APEX1. Antigen Species: Human
Schlagworte: | Anti-APE, Anti-APEX1, AP endonuclease 1 antibody, AP endonuclease class I antibody, AP lyase antibody, APE 1 antibody, APE... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €