Zu "K10161" wurden 55 Artikel gefunden!
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ODN 1668 (Type B) Endotoxin-free (sterile)
Artikelnummer: IAX-200-001-M001
3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 1720 (Cat. No.: IAX-200-200).
| Schlagworte: | CpG ODN TLR9 Agonist: B Type (species: rodent) |
| Anwendung: | TLR9 activator |
| MW: | 6383 D |
ab 218,00 €
E6446 dihydrochloride
Artikelnummer: TGM-T4068-100mg
Description: E6446 dihydrochloride is a novel synthetic antagonist for nucleic acid-sensing TLRs, potently suppressed DNA stimulation of HEK:TLR9 cells with IC50 of 10 nM. Target: TLR. Smiles: Cl.Cl.C(COc1ccc(cc1)-c1nc2ccc(OCCCN3CCCC3)cc2o1)CN1CCCC1. References: Lamphier M, et al. Novel small molecule inhibitors of...
| Anwendung: | TLR7 / TLR9 antagonist |
| CAS | 1345675-25-3 |
| MW: | 522.51 D |
ab 109,00 €
TLR9 (human) full length protein-synthetic nanodisc
Artikelnummer: DIM-FLP100146.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
| Schlagworte: | TLR9, CD289, Toll-like receptor 9, CD289, Human TLR9 full length protein-synthetic nanodisc |
| Anwendung: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 115.9 kD |
ab 1.291,00 €
ODN M362 (Type C) Endotoxin-free (sterile)
Artikelnummer: IAX-200-004-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2243 (Cat. No.: IAX-200-205).
| Schlagworte: | CpG ODN TLR9 Agonist: A Type (species: human and rodent) |
| Anwendung: | TLR9 activator |
| MW: | 6644 D |
ab 218,00 €
G-type iODN (inhibitory ODN) Endotoxin-free (sterile)
Artikelnummer: IAX-200-052-M001
Potent sequence of an inhibitory ODN of the poly-G class I targeting TLR9, but without effect on TLR7 and TLR8 signaling, for in vivo use in rodents (50-150 µg per injection). Negative control: Neutral-ODN (Cat. No.: IAX-200-202).
| Schlagworte: | Inhibitory ODN (iODN): Class I |
| Anwendung: | TLR9 competitor |
| MW: | 6735 D |
ab 179,00 €
ODN 1826 (Type B) Endotoxin-free (sterile)
Artikelnummer: IAX-200-002-M001
3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 1982 (Cat. No.: IAX-200-201).
| Schlagworte: | CpG ODN TLR9 Agonist: B Type (species: rodent) |
| Anwendung: | TLR9 activator |
| Spezies-Reaktivität: | mouse, rat |
| MW: | 6383 D |
ab 218,00 €
ODN 2006 (Type B) Endotoxin-free (sterile)
Artikelnummer: IAX-200-006-C100
3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.7-7.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2137 (Cat. No.: IAX-200-206).
| Schlagworte: | CpG ODN TLR9 Agonist: B Type (species: human and rodent) |
| Anwendung: | TLR9 activator |
| MW: | 7720 D |
ab 218,00 €
ODN 2216 (Type A) Endotoxin-free (sterile)
Artikelnummer: IAX-200-005-C100
3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2243 (Cat. No.: IAX-200-205).
| Schlagworte: | CpG ODN TLR9 Agonist: A Type (species: human and rodent) |
| Anwendung: | TLR9 activator |
| MW: | 6644 D |
ab 218,00 €
Anti-Toll-Like Receptor 9 (Clone 26C593.2)
Artikelnummer: Cay13593-1
The toll-like receptors (TLRs) in mammals comprise a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and an interleukin-1 (IL-1) receptor motif in the cytoplasmic domain. Like their counterparts in Drosophila, TLRs signal through adaptor...
| Schlagworte: | TLR9 |
| Anwendung: | WB, FC (intracellular, Cell surface), IHC (frozen/paraffin), ICC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
464,00 €
ODN 1585 (Type A) Endotoxin-free (sterile)
Artikelnummer: IAX-200-003-C100
3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2218 (Cat. No.: IAX-200-203). Unmethylated CG dinucleotides within particular sequence contexts are...
| Schlagworte: | CpG ODN TLR9 Agonist: A Type (species: rodent) |
| Anwendung: | TLR9 activator |
| MW: | 6643 D |
ab 218,00 €
iODN (inhibitory ODN) 2088 Endotoxin-free (sterile)
Artikelnummer: IAX-200-050-3001
3 x 1 mg. Potent sequence of an inhibitory ODN for in vivo use in rodents (50-150 µg per injection): prototype class I, may also affect TLR7 and TLR8 signaling. Negative control: Neutral-ODN (Cat. No.: IAX-200-202).
| Schlagworte: | Inhibitory ODN (iODN): Class I |
| Anwendung: | TLR9 competitor |
| MW: | 4887 D |
ab 179,00 €
ODN 2395 (Type C) Endotoxin-free (sterile)
Artikelnummer: IAX-200-007-C100
Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.7-7.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: Neutral-ODN (Cat. No.: IAX-200-202).
| Schlagworte: | CpG ODN: C Type (species: human and rodent) |
| Anwendung: | TLR9 activator |
| MW: | 7068 D |
ab 218,00 €