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Zu "K09455" wurden 71 Artikel gefunden!
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Artikelnummer: TGM-T34811-10mg
Description: Terrain, also known as NSC 291308, is a fungal metabolite with diverse biological activities. Terrein reduces age-related inflammation induced by oxidative stress through Nrf2/ERK1/2/HO-1 signalling in aged HDF cells. (+)-terrein suppresses interleukin-6/soluble interleukin-6 receptor induced-secretion...
Schlagworte: | NSC 291308, Terrain, (+)Terrein, NSC-291308, NSC291308 |
Anwendung: | Bioactive fungal metabolite |
CAS | 582-46-7 |
MW: | 154.16 D |
ab 289,00 €
Artikelnummer: TGM-T4028-100mg
Description: ML329 is a small molecule inhibitor of MITF, inhibiting TRPM-1 promoter activity. Target: TRP/TRPV Channel. Smiles: NS(=O)(=O)c1ccc(NC2=CC(=O)c3ccccc3C2=O)cc1. References: Faloon PW, et al. A Small Molecule Inhibitor of the MITF Molecular Pathway. Probe Reports from the NIH Molecular Libraries Program...
Anwendung: | MITF inhibitor |
CAS | 19992-50-8 |
MW: | 328.34 D |
ab 48,00 €
Artikelnummer: CSB-PA003243.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-MITF, Anti-BHLHE32, Anti-bHLHe32, Anti-Class E basic helix-loop-helix protein 32, Anti-Microphthalmia-associated... |
Anwendung: | ELISA, WB, IHC, IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 106,00 €
Artikelnummer: CSB-PA173368.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: MITF. Antigen Species: Human
Schlagworte: | Anti-MITF, Anti-BHLHE32, Anti-bHLHe32, Anti-Class E basic helix-loop-helix protein 32, Anti-Microphthalmia-associated... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 163,00 €
Artikelnummer: CSB-PA257242.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
Schlagworte: | Anti-MITF, Anti-BHLHE32, Anti-bHLHe32, Anti-Class E basic helix-loop-helix protein 32, Anti-Microphthalmia-associated... |
Anwendung: | ELISA, WB, IHC, IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
275,00 €
Artikelnummer: CSB-PA783063.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: MITF. Antigen Species: Human
Schlagworte: | Anti-MITF, Anti-BHLHE32, Anti-bHLHe32, Anti-Class E basic helix-loop-helix protein 32, Anti-Microphthalmia-associated... |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 163,00 €
Artikelnummer: NSJ-F41536-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific...
Schlagworte: | Anti-MITF, Anti-BHLHE32, Anti-bHLHe32, Anti-Class E basic helix-loop-helix protein 32, Anti-Microphthalmia-associated... |
Anwendung: | WB, IF, FC, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 326,00 €
Artikelnummer: Cay22481-5
ML-329 is an inhibitor of the microphthalmia-associated transcription factor (MITF) pathway with an IC50 value of 1.2 µM for promoter activity of the MITF target gene TRPM-1. It is selectively cytotoxic to the SK-MEL-5 and MALME-3M MITF-dependent melanoma cell lines over A375 MITF-independent cells (IC50s = 0.1,...
Schlagworte: | 4-[(1,4-dihydro-1,4-dioxo-2-naphthalenyl)amino]-benzenesulfonamide |
Anwendung: | MITF inhibitor |
CAS | 19992-50-8 |
MW: | 328.3 D |
ab 46,00 €
Artikelnummer: ABE-10-8004-100
MITF (Microphthalmia-associated transcription factor) is a basic helix-loop-helix leucine zipper (bHLH-Zip) family factor, involved in lineage-specific pathway regulation of many types of cells including osteoclasts, melanocytes, retinal pigment epithelial cells, mast cells and natural killer cells. It plays a...
Schlagworte: | Anti-MITF, Anti-BHLHE32, Anti-bHLHe32, Anti-Class E basic helix-loop-helix protein 32, Anti-Microphthalmia-associated... |
Anwendung: | IHC, WB |
Wirt: | Mouse |
Spezies-Reaktivität: | mouse, human |
418,00 €
-30 %
Rabattaktion
Artikelnummer: ARG56053.50
Protein function: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'- CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in...
Schlagworte: | Anti-MITF, Anti-bHLHe32, Anti-BHLHE32, Anti-Class E basic helix-loop-helix protein 32, Anti-Microphthalmia-associated... |
Anwendung: | FC, ICC, IF, IHC (paraffin) |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
608,00 €
425,60 €
Artikelnummer: G-HUFI00716.96
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
641,00 €
Artikelnummer: 200-301-H93
Anti-MITF Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with MITF from Human, Rat, and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-MITF from other sources has not been determined. Protein function: Transcription...
Schlagworte: | Anti-MITF, Anti-BHLHE32, Anti-bHLHe32, Anti-Class E basic helix-loop-helix protein 32, Anti-Microphthalmia-associated... |
Anwendung: | WB |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
756,00 €