Zu "K09186" wurden 21 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Anti-MLL1
Artikelnummer: A300-086A
Protein function: Histone methyltransferase that plays an essential role in early development and hematopoiesis. Catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac). In the...
| Schlagworte: | Anti-ALL1, Anti-KMT2A, EC=2.1.1.43 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
Anti-KMT2A
Artikelnummer: CSB-PA612015.100
Host Species: Rabbit. Isotype: IgG. Buffer: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific...
| Schlagworte: | Anti-ALL1, Anti-KMT2A, ALL-1 antibody, ALL1 antibody, C-terminal cleavage product of 180 kDa antibody, CXXC-type zinc... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
SNDX-5613
Artikelnummer: Cay40758-10
SNDX-5613 is a derivative of VTP-50469 (Cay-40759), an inhibitor of the protein-protein interaction between menin and mixed-lineage leukemia 1 (MLL1), also known as lysine methyltransferase 2A (KMT2A). It inhibits the growth of patient-derived acute myeloid leukemia (AML) cells expressing the gene encoding upstream...
| Schlagworte: | Revumenib,... |
| Anwendung: | VTP-50469 (MLL1-menin-interaction inhibitor) derivative |
| CAS | 2169919-21-3 |
| MW: | 630.8 D |
ab 163,00 €
Anti-MLL1
Artikelnummer: A300-374A
Protein function: Histone methyltransferase that plays an essential role in early development and hematopoiesis. Catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac). In the...
| Schlagworte: | Anti-ALL1, Anti-KMT2A, EC=2.1.1.43 |
| Anwendung: | WB, IP, ChIP, ChIP-chip |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
MLL1 (human recombinant)
Artikelnummer: Cay10658-100
Mixed Lineage Leukemia (MLL1) plays a major role in epigenetic regulation through methylation of histone 3 at lysine 4 (H3K4) to activate gene transcription. Methylation of H3K4 leads to upregulation of developmental genes, including HOX family members. In addition to its methylation activity, MLL1 has been shown to...
| Schlagworte: | ALL1, p320, p180, KMT2A, ALL-1, Trithorax-like protein, Zinc finger protein HRX, MLL cleavage product N320, MLL cleavage... |
| Anwendung: | Enzyme kinetics, Methylation studies |
| Ursprungsart: | human |
| MW: | 24,1 kD |
472,00 €
Anti-MLL1 Recombinant Monoclonal
Artikelnummer: A700-010
Protein function: Histone methyltransferase that plays an essential role in early development and hematopoiesis. Catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac). In the...
| Schlagworte: | Anti-ALL1, Anti-KMT2A, EC=2.1.1.43 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 185,00 €
Anti-KMT2A / MLL (N320), clone N4.4
Artikelnummer: ARG54797.50
Protein function: Histone methyltransferase that plays an essential role in early development and hematopoiesis. Catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac). In the...
| Schlagworte: | Anti-ALL1, Anti-KMT2A, EC=2.1.1.43 |
| Anwendung: | ChIP, IHC (paraffin), IP, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse |
608,00 €
Anti-MLL1
Artikelnummer: A300-087A
Protein function: Histone methyltransferase that plays an essential role in early development and hematopoiesis. Catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac). In the...
| Schlagworte: | Anti-ALL1, Anti-KMT2A, EC=2.1.1.43 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
MLL1 Complex Direct Activity Assay Kit
Artikelnummer: BPS-53008
The MLL1 Complex Direct Activity Assay kit is designed to measure MLL1 activity for screening and profiling applications, using purified MLL1 and its complex components: WDR5, RbBP5,Ash2, and DPY30. The MLL1 Complex Direct Activity Assay Kit comes in a convenient format, with a 96-well plate precoated with histone...
| Schlagworte: | MLL, ALL1, p180, p320, KMT2A, ALL-1, EC=2.1.1.43, Trithorax-like protein, Zinc finger protein HRX, MLL cleavage product... |
| Anwendung: | MLL1 activity assays, Enzyme kinetics, HTS |
1.182,00 €
MI-3
Artikelnummer: Cay27214-5
MI-3 is an inhibitor of the interaction between menin and mixed lineage leukemia (MLL) fusion proteins (IC50 = 648 nM). MI-3 binds to menin (Kd = 201 nM) and inhibits the menin interaction with the MLL fusion protein MLL-AF9 in HEK293 cells without affecting protein levels of menin or MLL-AF9. It inhibits growth of...
| Schlagworte: | 4-[4-(4,5-dihydro-5,5-dimethyl-2-thiazolyl)-1-piperazinyl]-6-(1-methylethyl)-thieno[2,3-d]pyrimidine |
| Anwendung: | MLL / menin interaction inhibitor |
| CAS | 1271738-59-0 |
| MW: | 375.6 D |
ab 52,00 €
Anti-KMT2A
Artikelnummer: G-PACO07353.50
KMT2A Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human, Mouse, Rat and for use in ELISA, IHC applications. KMT2A Antibody is a high quality polyclonal antibody for research use only.. Protein function: Histone methyltransferase that plays an essential role in early development and...
| Schlagworte: | Anti-ALL1, Anti-KMT2A |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
341,00 €
Anti-KMT2A
Artikelnummer: ATA-HPA044910.100
Protein function: Histone methyltransferase that plays an essential role in early development and hematopoiesis. Catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys- 4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac). In the...
| Schlagworte: | Anti-ALL1, Anti-KMT2A |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 320,00 €