Zu "K09093" wurden 136 Artikel gefunden!

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Indoxyl Sulfate-d5 potassium salt
Indoxyl Sulfate-d5 potassium salt

Artikelnummer: TGM-T70313-100mg

Description: Indoxyl sulfate-d5 is intended for use as an internal standard for the quantification of indoxyl sulfate by GC- or LC-MS. Indoxyl sulfate is a uremic toxin and a metabolite of tryptophan. It is formed via sulfation of indole, an intermediate generated from tryptophan by intestinal bacteria, by the...
Anwendung: GC-MS, LC-MS internal standard, quantification
CAS 1644451-34-2
MW: 256.3278 D
ab 1.491,00 €
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ITE
ITE

Artikelnummer: TGM-T7202-100mg

Description: ITE is a potent endogenous agonist of the aryl hydrocarbon receptor (AhR) (Ki: 3 nM) with immunosuppressive activity. Target: AhR, Aryl Hydrocarbon Receptor. Smiles: COC(=O)c1csc(n1)C(=O)c1c[nH]c2ccccc12. References: Pang L P , Li Y , Zou Q Y , et al. ITE inhibits growth of human pulmonary artery...
Anwendung: Endogenous AhR agonist
CAS 448906-42-1
MW: 286.31 D
ab 34,00 €
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SGA360
SGA360

Artikelnummer: TGM-T8980-100mg

Description: SGA360 is a selective aryl hydrocarbon (Ah) receptor modulator. It exhibits anti-inflammatory properties. Target: Aryl Hydrocarbon Receptor. Smiles: C(C=C)N1C=2C(C(=N1)C3=C(OC)C=C(OC)C=C3)=CC=CC2C(F)(F)F. References: Muku G E , Lahoti T S , Murray I A , et al. Ligand-mediated cytoplasmic retention of...
Anwendung: AHR modulator
CAS 680611-86-3
MW: 362.35 D
ab 39,00 €
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5-methyl Chrysene
5-methyl Chrysene

Artikelnummer: TGM-T84400-10mg

Description: 5-Methylchrysene, a carcinogenic polycyclic aromatic hydrocarbon with four fused rings, functions as an aryl hydrocarbon receptor agonist. It is generated through the incomplete combustion of organic matter and primarily detected in gasoline exhaust and tobacco smoke. Additionally, 5-Methylchrysene can...
Schlagworte: NSC 407620
Anwendung: AH receptor agonist
CAS 3697-24-3
MW: 242.3 D
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CAY10464
CAY10464

Artikelnummer: TGM-T84540-10mg

Description: CAY10464 (AHR antagonist 7) is a potent AHR antagonist with potential antitumor activity that inhibits CYP1A1 mRNA expression and may be used to study cancer and metabolic diseases. Target: AhR. Smiles: C(=C/C1=CC(Cl)=CC(Cl)=C1)\C2=CC=C(OC)C=C2
Schlagworte: AHR antagonist 7
Anwendung: AhR antagonist
CAS 688348-37-0
MW: 279.16 D
ab 40,00 €
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AHR Protein, Human, Recombinant (His)
AHR Protein, Human, Recombinant (His)

Artikelnummer: TGM-TMPH-00958-100ug

Description: AHR Protein, Human, Recombinant (His) is expressed in E. coli.
Schlagworte: Class E basic helix-loop-helix protein 76, Aryl hydrocarbon receptor, bHLHe76, Ah receptor
MW: 29.0 kD
ab 278,00 €
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L-Kynurenine-d4
L-Kynurenine-d4

Artikelnummer: TGM-TMID-0071-1mg

Description: L-Kynurenine-d4 is a deuterated compound of L-Kynurenine. L-Kynurenine has a CAS number of 2922-83-0. L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has...
Anwendung: GC-MS, LC-MS internal standard, quantification, AHR ligand
CAS 2672568-86-2
MW: 212.24 D
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FICZ
FICZ

Artikelnummer: TGM-TQ0257-1mg

Description: FICZ (6-Formylindolo[3,2-b]carbazole) is a potent aryl agonist for the hydrocarbon receptor (AhR, Kd: 70 pM). Target: Aryl Hydrocarbon Receptor. Smiles: O=Cc1c2[nH]c3ccccc3c2cc2[nH]c3ccccc3c12. References: Mohammadi-Bardbori A, et al. The highly bioactive molecule and signal substance...
Schlagworte: 6-Formylindolo[3,2-b]carbazole
Anwendung: AhR agonist
CAS 172922-91-7
MW: 284.31 D
ab 47,00 €
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StemRegenin 1
StemRegenin 1

Artikelnummer: TGM-T1831-100mg

Description: StemRegenin 1 (SR1) is an aryl hydrocarbon receptor (AhR) inhibitor. Target: AhR, Aryl Hydrocarbon Receptor. Smiles: CC(C)n1cnc2c(NCCc3ccc(O)cc3)nc(nc12)-c1csc2ccccc12. References: Boitano AE, et al. Science, 2010, 329(5997), 1345-1348.
Schlagworte: SR1
Anwendung: Aryl hydrocarbon receptor inhibitor
CAS 1227633-49-9
MW: 429.54 D
ab 33,00 €
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VAF347
VAF347

Artikelnummer: TGM-T13276-100mg

Description: VAF347 is a cell-permeable and highly affinity agonist of the aryl hydrocarbon receptor (AhR) with anti-inflammatory effects. Target: Aryl Hydrocarbon Receptor. Smiles: FC(F)(F)c1ccc(Nc2nccc(n2)-c2cccc(Cl)c2)cc1. References: Ibabao CN, et al. The AhR agonist VAF347 augments retinoic acid-induced...
Anwendung: AhR agonist
CAS 574759-62-9
MW: 349.74 D
ab 34,00 €
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5-fluoro 203
5-fluoro 203

Artikelnummer: TGM-T21704-1mg

Description: 5-fluoro 203 (NSC-703786) is a cytotoxic molecule leading to cell death by forming DNA adducts. 5-fluoro 203 induces aryl hydrocarbon receptor signaling, and elevates expression of CYP1A1. 5-fluoro 203 treatment of cells also leads to elevation of reactive oxygen species and activation of p38, JNK and...
Schlagworte: 5F-203, NSC-703786
Anwendung: Aryl hydrocarbon receptor activator
CAS 260443-89-8
MW: 258.31 D
ab 39,00 €
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Evodiamine
Evodiamine

Artikelnummer: TGM-T2868-100mg

Description: Evodiamine (d-Evodiamine) is an alkaloid isolated from the fruit of daylily and has a variety of biological activities including anti-inflammatory, anti-obesity and anti-tumor. Target: Prostaglandin Receptor. Smiles: CN1[C@@]2(C3=C(C=4C(N3)=CC=CC4)CCN2C(=O)C=5C1=CC=CC5)[H]. References: Lee TJ, et al....
Schlagworte: (+)-Evodiamine, d-Evodiamine, Isoevodiamine
Anwendung: Quinazoline alkaloid, AhR antagonist, K05222 activator
CAS 518-17-2
MW: 303.36 D
ab 42,00 €
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