Zu "K08871" wurden 78 Artikel gefunden!
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Anti-BRD2
Artikelnummer: A302-583A
Protein function: May play a role in spermatogenesis or folliculogenesis. Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly. [The UniProt Consortium]
| Schlagworte: | Anti-BRD2, Anti-O27.1.1, Anti-KIAA9001, Anti-Bromodomain-containing protein 2, Anti-Really interesting new gene 3 protein |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 178,00 €
Bromodomain-containing protein 2 (BRD2), partial,...
Artikelnummer: CSB-YP002800HU.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 339-459aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: QSSKKGKLSE QLKHCNGILK ELLSKKHAAY AWPFYKPVDA SALGLHDYHD IIKHPMDLST VKRKMENRDY RDAQEFAADV RLMFSNCYKY NPPDHDVVAM ARKLQDVFEF RYAKMPDEPL E. Purity: Greater than...
| Schlagworte: | BRD2, O27.1.1, KIAA9001, Bromodomain-containing protein 2, Really interesting new gene 3 protein |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | human |
| MW: | 16.0 kD |
ab 265,00 €
Bromodomain-containing protein 2 (BRD2), partial,...
Artikelnummer: CSB-YP002800HU1.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 65-187aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: EVSNPKKPGR VTNQLQYLHK VVMKALWKHQ FAWPFRQPVD AVKLGLPDYH KIIKQPMDMG TIKRRLENNY YWAASECMQD FNTMFTNCYI YNKPTDDIVL MAQTLEKIFL QKVASMPQEE QEL. Purity: Greater...
| Schlagworte: | BRD2, O27.1.1, KIAA9001, Bromodomain-containing protein 2, Really interesting new gene 3 protein |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | human |
| MW: | 16.6 kD |
ab 265,00 €
Anti-BRD2
Artikelnummer: ATA-HPA074612.100
Polyclonal Antibody against Human BRD2, Gene description: bromodomain containing 2, Alternative Gene Names: BRD2-IT1, D6S113E, FSRG1, KIAA9001, NAT, RING3, Validated applications: ICC, Uniprot ID: P25440, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: May...
| Schlagworte: | Anti-BRD2, Anti-O27.1.1, Anti-KIAA9001, Anti-Bromodomain-containing protein 2, Anti-Really interesting new gene 3 protein |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
477,00 €
PLX51107
Artikelnummer: TGM-TQ0253-100mg
Description: PLX51107 is a potent and selective BET inhibitor with Kds of 1.6, 2.1, 1.7, and 5 nM for BRD2-BD1, BRD3-BD1, BRD4-BD1, and BRDT-BD1, respectively. Target: Epigenetic Reader Domain. Smiles: C[C@@H](c1ccccn1)n1cc(-c2ccc(cc2)C(O)=O)c2ncc(cc12)-c1c(C)noc1C. References: Ozer HG, et al. BRD4 Profiling...
| Anwendung: | BET family protein inhibitor |
| CAS | 1627929-55-8 |
| MW: | 438.48 D |
ab 52,00 €
Bromodomain inhibitor-8
Artikelnummer: TGM-T10621-100mg
Description: Bromodomain inhibitor-8 is an inhibitor of BET bromodomain used to treat autoimmune and inflammatory diseases. Target: Others. Smiles: COC(=O)c1ccc(cc1)-c1ccc2N([C@@H](C)C[C@@H](Nc3ccc(Cl)cc3)c2c1)C(C)=O. References: CHUNG, Chun-Wa, et al. BROMODOMAI NINHIBITOR SFORTREATI NG AUTOIMMUNE AND INFLAMMATORY...
| Anwendung: | Bromodomain inhibitor |
| CAS | 1300031-70-2 |
| MW: | 448.94 D |
ab 345,00 €
BET bromodomain inhibitor
Artikelnummer: TGM-T2072-100mg
Description: BET bromodomain inhibitor is a potent BET inhibitor. Target: Epigenetic Reader Domain. Smiles: Cc1noc2[C@H](CC(N)=O)N=C(c3ccc(Cl)cc3)c3cc(ccc3-c12)-c1cnn(C)c1. References: Xiao Y, et al. Rheumatology (Oxford). 2015 Aug 31.
| Anwendung: | BET bromodomain inhibitor |
| CAS | 1505453-59-7 |
| MW: | 445.9 D |
ab 42,00 €
I-BET151
Artikelnummer: TGM-T2120-1mg
Description: I-BET151 (GSK1210151A) (GSK1210151A) is a specific BET inhibitor for BRD2/3/4 (IC50: 0.5/0.25/0.79 µM, in cell-free assays). Target: Epigenetic Reader Domain. Smiles: Cl.COc1cc2c3n([C@H](C)c4ccccn4)c(=O)[nH]c3cnc2cc1-c1c(C)noc1C. References: Dawson MA, et al. Nature, 2011, 478(7370), 529-533.
| Schlagworte: | GSK1210151A |
| Anwendung: | pan-BET family inhibitor |
| CAS | 1300031-49-5 |
| MW: | 415.44 D |
ab 42,00 €
Trotabresib
Artikelnummer: TGM-T36395-100mg
Description: Trotabresib (CC-90010) is an orally active inhibitor of BET and can be used in studies about advanced solid tumors. Target: Epigenetic Reader Domain. Smiles: Cn1cc(-c2cc(ccc2OCC2CC2)S(C)(=O)=O)c2ccccc2c1=O. References: CELGENE QUANTICEL RESEARCH, INC. PROCESS FOR THE PREPARATIO NOFBROMODO MAININHIBI...
| Schlagworte: | CC-90010 |
| Anwendung: | Targets bromodomain-containing protein 2 (BRD2) |
| CAS | 1706738-98-8 |
| MW: | 383.46 D |
ab 83,00 €
INCB-057643
Artikelnummer: TGM-T5417-100mg
Description: INCB057643 is a potent, selective and orally bioavailable BET inhibitor. Target: Apoptosis, Epigenetic Reader Domain. Smiles: CN1C(=O)C(C)(C)Oc2c1cc(cc2-c1cn(C)c(=O)c2[nH]ccc12)S(C)(=O)=O. References: Matthew C. Stubbs, et al. Abstract 5071: Preclinical characterization of the potent and selective BET...
| Anwendung: | BET family protein inhibitor |
| CAS | 1820889-23-3 |
| MW: | 415.46 D |
ab 37,00 €
Birabresib
Artikelnummer: TGM-T6032-100mg
Description: Birabresib (MK-8628) is a synthetic, small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins 2, 3 and 4 with potential antineoplastic activity. Target: Epigenetic Reader Domain. Smiles:...
| Schlagworte: | OTX015 (MK 8628/Birabresib), MK-8628, OTX-015 |
| Anwendung: | Targets bromodomain-containing protein 2 (BRD2) |
| CAS | 202590-98-5 |
| MW: | 491.99 D |
ab 42,00 €
BET bromodomain inhibitor 2
Artikelnummer: TGM-T62655-100mg
Description: BET bromodomain inhibitor 2 is a potent inhibitor of the BET-type bromodomain with an IC50 of 14.1 µM. Target: Others. Smiles: S(N(CC)CC)(=O)(=O)C1=CC(=C(C=C1)[C@H]2CC(=O)N(C)C2)C3=CC(OC)=C(OC)C=C3
| Anwendung: | BET bromodomain inhibitor |
| CAS | 2414195-69-8 |
| MW: | 446.56 D |
ab 2.142,00 €