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Zu "K08865" wurden 50 Artikel gefunden!
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NEU
Artikelnummer: CSB-EP822241HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-322aa. Protein Length: Full Length. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MEGISNFKTP SKLSEKKKSV LCSTPTINIP ASPFMQKLGF GTGVNVYLMK RSPRGLSHSP WAVKKINPIC NDHYRSVYQK RLMDEAKILK SLHHPNIVGY RAFTEANDGS LCLAMEYGGE KSLNDLIEER YKASQDPFPA...
Schlagworte: | PBK, SPK, CT84, TOPK, Nori-3, EC=2.7.12.2, PDZ-binding kinase, Cancer/testis antigen 84, MAPKK-like protein kinase, T-LAK... |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 63.1 kD |
ab 213,00 €
NEU
Artikelnummer: CSB-EP822241HUb0.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-322aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MEGISNFKTP SKLSEKKKSV LCSTPTINIP ASPFMQKLGF GTGVNVYLMK RSPRGLSHSP WAVKKINPIC NDHYRSVYQK RLMDEAKILK SLHHPNIVGY RAFTEANDGS LCLAMEYGGE KSLNDLIEER...
Schlagworte: | PBK, SPK, CT84, TOPK, Nori-3, EC=2.7.12.2, PDZ-binding kinase, Cancer/testis antigen 84, MAPKK-like protein kinase, T-LAK... |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 42.1 kD |
ab 213,00 €
NEU
Artikelnummer: CSB-PA030267.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-phospho-SPK, Anti-phospho-PBK, Anti-phospho-CT84, Anti-phospho-TOPK, Anti-phospho-Nori-3, EC=2.7.12.2,... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 106,00 €
NEU
Artikelnummer: CSB-PA030268.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-SPK, Anti-PBK, Anti-CT84, Anti-TOPK, Anti-Nori-3, EC=2.7.12.2, Anti-PDZ-binding kinase, Anti-Cancer/testis antigen... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, monkey |
ab 106,00 €
Artikelnummer: Cay17052-500
OTS964 is an inhibitor of lymphokine-activated killer T cell-originated protein kinase (TOPK, IC50 = 28 nM). It specifically blocks cytokinesis, leading to apoptosis, in a broad range of cancer cells. OTS964 induces apoptosis of human lung cancer cells in mouse xenografts.Formal Name:...
Schlagworte: | 9-[4-[(1R)-2-(dimethylamino)-1-methylethyl]phenyl]-8-hydroxy-6-methyl-thieno[2,3-c]quinolin-4(5H)-one, monohydrochloride |
Anwendung: | PBK / TOPK inhibitor |
CAS | 1338545-07-5 |
MW: | 429 D |
ab 66,00 €
Artikelnummer: Cay19815-5
HI TOPK 032 is an inhibitor of lymphokine-activated killer T cell-originated protein kinase (TOPK), blocking phosphorylation of the substrate histone H2AX with an IC50 value of ~2 µM and providing complete inhibition at 5 µM. It also inhibits checkpoint kinase 1 (Chk1, IC50 = 9.6 µM). In addition, HI TOPK 032...
Schlagworte: | N-(12-cyanoindolizino[2,3-b]quinoxalin-2-yl)-2-thiophenecarboxamide |
Anwendung: | PBK inhibitor |
CAS | 487020-03-1 |
MW: | 369.4 D |
ab 46,00 €
-15 %
Rabattaktion
Artikelnummer: A302-194A
Protein function: Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage. [The UniProt...
Schlagworte: | Anti-PBK, Anti-SPK, Anti-TOPK, Anti-CT84, Anti-Nori-3, EC=2.7.12.2, Anti-PDZ-binding kinase, Anti-Cancer/testis antigen... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
164,00 €
ab 139,40 €
-15 %
Rabattaktion
Artikelnummer: A302-195A
Protein function: Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage. [The UniProt...
Schlagworte: | Anti-PBK, Anti-SPK, Anti-TOPK, Anti-CT84, Anti-Nori-3, EC=2.7.12.2, Anti-PDZ-binding kinase, Anti-Cancer/testis antigen... |
Anwendung: | WB, IP, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
164,00 €
ab 139,40 €
Artikelnummer: NSJ-R31723
0.5mg/ml if reconstituted with 0.2ml sterile DI water. PDZ binding kinase (PBK), also known as TOPK, is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. PBK can mediate cell growth through histone H3 modification. Evidence suggests that mitotic...
Schlagworte: | Anti-SPK, Anti-PBK, Anti-TOPK, Anti-CT84, Anti-Nori-3, EC=2.7.12.2, Anti-PDZ-binding kinase, Anti-Cancer/testis antigen... |
Anwendung: | WB, IHC (paraffin), IF/ICC, FC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Artikelnummer: ARG57886.100
Protein function: Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage. [The UniProt...
Schlagworte: | Anti-SPK, Anti-PBK, Anti-TOPK, Anti-CT84, Anti-Nori-3, EC=2.7.12.2, Anti-PDZ-binding kinase, Anti-Cancer/testis antigen... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
624,00 €
Artikelnummer: Cay17053-1
OTS514 is an inhibitor of lymphokine-activated killer T cell-originated protein kinase (TOPK, IC50 = 2.6 nM), a serine-threonine kinase often overexpressed and transactivated in several types of cancer. OTS514 (10 nM) selectively inhibits growth of patient-derived acute myeloid leukemia (AML) cells over normal CD34+...
Schlagworte: | 9-[4-[(1R)-2-amino-1-methylethyl]phenyl]-8-hydroxy-6-methyl-thieno[2,3-c]quinolin-4(5H)-one |
Anwendung: | TOPK inhibitor |
CAS | 1338540-63-8 |
MW: | 364.5 D |
ab 125,00 €
Artikelnummer: ARG57923.100
Protein function: Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage. [The UniProt...
Schlagworte: | Anti-phospho-PBK, Anti-phospho-SPK, Anti-phospho-CT84, Anti-phospho-TOPK, Anti-phospho-Nori-3, EC=2.7.12.2,... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
584,00 €