Zu "K08849" wurden 44 Artikel gefunden!
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Human MLKL (Mixed Lineage Kinase Domain Like Protein)...
Artikelnummer: ELK-ELK7715.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human MLKL. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human MLKL. Next,...
| Schlagworte: | hMLKL, Mixed lineage kinase domain-like protein |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
GW 806742X
Artikelnummer: Cay37541-10
GW 806742X is an inhibitor of necroptosis. It binds to mixed lineage kinase domain-like protein (Mlkl, Kd = 9.3 µM for the mouse protein), reducing its association with the cytoplasmic membrane, and decreases necroptosis induced by TNF-alpha, a Smac mimetic, and the caspase inhibitor Q-VD-OPH (Cay-15260) in isolated...
| Schlagworte: | 3-[[4-[methyl[4-[[[[4-(trifluoromethoxy)phenyl]amino]carbonyl]amino]phenyl]amino]-2-pyrimidinyl]amino]-benzenesulfonamide |
| Anwendung: | Necroptosis inhibitor |
| CAS | 579515-63-2 |
| MW: | 573.5 D |
ab 74,00 €
Necrosulfonamide
Artikelnummer: Cay20844-5
Necrosulfonamide is a small molecule that inhibits necroptosis by blocking mixed lineage kinase domain-like protein (MLKL), a key substrate of receptor-interacting serine-threonine kinase 3 (RIPK3). Necrosulfonamide has been shown to prevent the MLKL-RIPK1-RIPK3 necrosome complex from interacting with downstream...
| Schlagworte: | (2E)-N-[4-[[(3-methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide |
| Anwendung: | Necroptosis inhibitor, MLKL inhibitor |
| CAS | 1360614-48-7 |
| MW: | 461.5 D |
ab 66,00 €
Necrosulfonamide
Artikelnummer: AG-CR1-3705-M005
Off-white to yellow solid. Soluble in DMSO (20mg/ml) or DMF (20mg/ml). Insoluble in water. Chemical. CAS: 1360614-48-7. Formula: C18H15N5O6S2. MW: 461.5. Inhibitor of necroptosis, by blocking mixed lineage kinase domain-like protein (MLKL), a key substrate of receptor-interacting serine-threonine kinase 3 (RIP3)....
| Schlagworte: | NSA, (2E)-N-[4-[[(3-methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide |
| Anwendung: | Necroptosis inhibitor, MLKL inhibitor |
| CAS | 1360614-48-7 |
| MW: | 461,5 D |
ab 55,00 €
Phytic acid . sodium salt . hydrate
Artikelnummer: AG-CN2-0528-M025
Isolated from Oryza sativa. Direct activator of necroptosis inducer MLKL (mixed lineage kinase domain-like). Necroptosis is an inflammatory form of programmed cell death executed through plasma membrane rupture by the pseudokinase mixed lineage kinase domain-like (MLKL). Addition of IP6 promotes membrane...
| Schlagworte: | D-myo-Inositol-1,2,3,4,5,6-hexaphosphate sodium salt hydrate, IP6 |
| Anwendung: | Iron (Fe) chelator, Anticancer, antiinflammatory, antidiabetic, neuroprotective antioxidant |
| MW: | 660 D |
ab 44,00 €
Anti-MLKL
Artikelnummer: ARG56456.100
Protein function: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane...
| Schlagworte: | Anti-hMLKL, Anti-Mixed lineage kinase domain-like protein |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
624,00 €
Anti-Mlkl, CT (Mlkl, Mixed lineage kinase domain-like...
Artikelnummer: 038472-APC.200
Applications:, Suitable for use in Western Blot and FLISA. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute...
| Schlagworte: | Anti-Mlkl, Anti-Mixed lineage kinase domain-like protein |
| Anwendung: | FLISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
993,00 €
Anti-Mlkl, CT (Mlkl, Mixed lineage kinase domain-like...
Artikelnummer: 038472-Biotin.200
Applications:, Suitable for use in Western Blot and ELISA. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and...
| Schlagworte: | Anti-Mlkl, Anti-Mixed lineage kinase domain-like protein |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
993,00 €
Anti-Mlkl, CT (Mlkl, Mixed lineage kinase domain-like...
Artikelnummer: 038472-FITC.200
Applications:, Suitable for use in Western Blot and FLISA. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and...
| Schlagworte: | Anti-Mlkl, Anti-Mixed lineage kinase domain-like protein |
| Anwendung: | FLISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
993,00 €
Anti-Mlkl, CT (Mlkl, Mixed lineage kinase domain-like...
Artikelnummer: 038472-HRP.200
Applications:, Suitable for use in Western Blot and ELISA. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and...
| Schlagworte: | Anti-Mlkl, Anti-Mixed lineage kinase domain-like protein |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
993,00 €
Anti-Mlkl, CT (Mlkl, Mixed lineage kinase domain-like...
Artikelnummer: 038472.200
Applications:, Suitable for use in Western Blot and ELISA. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000-1:2000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at...
| Schlagworte: | Anti-Mlkl, Anti-Mixed lineage kinase domain-like protein |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
728,00 €
Anti-MLKL, clone 8H7
Artikelnummer: E-AB-22249.120
This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain, however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death...
| Schlagworte: | Anti-hMLKL, Anti-Mixed lineage kinase domain-like protein, MLKL Monoclonal Antibody |
| Anwendung: | IHC (paraffin) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 72,00 €