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RIP2 kinase inhibitor 1
Artikelnummer: TGM-T12727-100mg
Description: RIP2 kinase inhibitor 1 is a potent and selective receptor interacting inhibitor of protein 2 (RIP2) kinase(RIP2 FP with an IC50 of 0.03 µM ),and is used for autoinflammatory disorders. Target: Others. Smiles: C(N)(=O)C=1C(=NN2C1N[C@]3(C[C@@](C2)(C[C@@H]3O)[H])[H])C=4C=C5C(=CC4)SC=N5. References:...
| Anwendung: | RIP2 kinase inhibitor |
| CAS | 2380028-10-2 |
| MW: | 355.41 D |
ab 2.080,00 €
RIP2 Kinase Inhibitor 3
Artikelnummer: TGM-T12728-100mg
Description: RIP2 Kinase Inhibitor 3 is a potent and selective inhibitor of RIP2, demonstrating an IC50 of 1 nM. Target: RIP kinase, Others. Smiles: COc1cc2nccc(Nc3n[nH]c(C)c3C)c2cc1S(=O)(=O)C(C)(C)C. References: Haile PA, et al. Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic...
| Anwendung: | RIP2 Kinase inhibitor |
| CAS | 1398053-50-3 |
| MW: | 388.48 D |
ab 52,00 €
RIP2 kinase inhibitor 2
Artikelnummer: TGM-T16753-100mg
Description: RIP2 kinase inhibitor 2 is a compound that inhibits receptor-interacting protein-2 kinase (RIP2). Target: Others. Smiles: COCCOc1cc2nccc(Nc3n[nH]c(C)c3C)c2cc1S(=O)(=O)C(C)(C)C. References: Linda N. Casillas, et al. Amino-quinolines as kinase inhibitors. PCT Int. Appl. (2014), WO 2014043437 A1 20140320.
| Anwendung: | RIP2 kinase inhibitor |
| CAS | 1581270-11-2 |
| MW: | 432.54 D |
ab 191,00 €
GSK583
Artikelnummer: TGM-T3537-100mg
Description: GSK583 is a highly effective and specific RIP2 kinase inhibitor (IC50: 5 nM). Target: RIP kinase. Smiles: CC(C)(C)S(=O)(=O)c1ccc2nccc(Nc3n[nH]c4ccc(F)cc34)c2c1. References: Haile PA, et al. J Med Chem. 2016, 59(10):4867-80.
| Anwendung: | Selective RIPK2 inhibitor |
| CAS | 1346547-00-9 |
| MW: | 398.45 D |
ab 46,00 €
RIP2 Kinase Inhibitor 4
Artikelnummer: TGM-T39574-25mg
Description: RIP2 Kinase Inhibitor 4 is a highly potent and selective RIPK2 PROTAC compound that efficiently degrades RIPK2 (pIC50 value of 8) and effectively inhibits the release of TNF-alpha. Target: Others. Smiles:...
| Anwendung: | RIP2 Kinase inhibitor |
| CAS | 2126803-41-4 |
| MW: | 1045.23 D |
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WEHI-345
Artikelnummer: TGM-T3997-2mg
Description: WEHI-345 is a potent and selective RIPK2 inhibitor that modulates NOD signaling events while preventing inflammatory cytokine production. Target: RIP kinase. Smiles: Cc1ccc(cc1)-c1nn(c2ncnc(N)c12)C(C)(C)CNC(=O)c1ccncc1. References: Nachbur U, et al. A RIPK2 inhibitor delays NOD signalling events yet...
| Schlagworte: | WEHI345 |
| Anwendung: | RIPK2 inhibitor |
| CAS | 1354825-58-3 |
| MW: | 401.46 D |
78,00 €
RIPK2 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-02008-100ug
Description: RIPK2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 65.2 kDa and the accession number is O43353.
| Schlagworte: | Receptor-interacting serine/threonine-protein kinase 2, RIPK2, Tyrosine-protein kinase RIPK2, RIP-like-interacting CLARP... |
| MW: | 65.2 kD |
ab 193,00 €
GSK583
Artikelnummer: Cay19739-10
GSK583 is a selective inhibitor of RIP-like interacting CLARP kinase (RICK also known as RIP2 kinase, IC50 = 5 nM). RIP2 Kinase is a central component of the innate immune system and enables downstream signaling following activation of the pattern recognition receptors NOD1 and NOD2, leading to the production of...
| Schlagworte: | 6-[(1,1-dimethylethyl)sulfonyl]-N-(5-fluoro-1H-indazol-3-yl)-4-quinolinamine |
| Anwendung: | Selective RIPK2 inhibitor |
| CAS | 1346547-00-9 |
| MW: | 398.5 D |
ab 60,00 €
Receptor-interacting serine/threonine-protein kinase 2...
Artikelnummer: CSB-EP019736HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-540aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MNGEAICSAL PTIPYHKLAD LRYLSRGASG TVSSARHADW RVQVAVKHLH IHTPLLDSER KDVLREAEIL HKARFSYILP ILGICNEPEF LGIVTEYMPN GSLNELLHRK TEYPDVAWPL RFRILHEIAL...
| Schlagworte: | RIPK2, RIP-2, CARDIAK, EC=2.7.10.2, EC=2.7.11.1, Tyrosine-protein kinase RIPK2, Receptor-interacting protein 2,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 65.2 kD |
ab 213,00 €
Receptor-interacting serine/threonine-protein kinase 2...
Artikelnummer: CSB-EP019736HUc7.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-540aa. Protein Length: Full Length. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: MNGEAICSAL PTIPYHKLAD LRYLSRGASG TVSSARHADW RVQVAVKHLH IHTPLLDSER KDVLREAEIL HKARFSYILP ILGICNEPEF LGIVTEYMPN GSLNELLHRK TEYPDVAWPL RFRILHEIAL...
| Schlagworte: | RIPK2, RIP-2, CARDIAK, EC=2.7.10.2, EC=2.7.11.1, Tyrosine-protein kinase RIPK2, Receptor-interacting protein 2,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 62.0 kD |
ab 213,00 €
Receptor-interacting serine/threonine-protein kinase 2...
Artikelnummer: CSB-EP019736HUe0.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-540aa. Protein Length: Full Length. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MNGEAICSAL PTIPYHKLAD LRYLSRGASG TVSSARHADW RVQVAVKHLH IHTPLLDSER KDVLREAEIL HKARFSYILP ILGICNEPEF LGIVTEYMPN GSLNELLHRK TEYPDVAWPL RFRILHEIAL GVNYLHNMTP...
| Schlagworte: | RIPK2, RIP-2, CARDIAK, EC=2.7.10.2, EC=2.7.11.1, Tyrosine-protein kinase RIPK2, Receptor-interacting protein 2,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 87.9 kD |
ab 213,00 €
Anti-Phospho-RIPK2 (S176)
Artikelnummer: CSB-PA070142.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-RIPK2, Anti-phospho-RIP-2, Anti-phospho-CARDIAK, EC=2.7.10.2, EC=2.7.11.1, Anti-phospho-Tyrosine-protein... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 106,00 €