Zu "K08806" wurden 42 Artikel gefunden!
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Serine/threonine-protein kinase pim-2 (PIM2), human,...
Artikelnummer: CSB-EP873725HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-311aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MLTKPLQGPP APPGTPTPPP GGKDREAFEA EYRLGPLLGK GGFGTVFAGH RLTDRLQVAI KVIPRNRVLG WSPLSDSVTC PLEVALLWKV GAGGGHPGVI RLLDWFETQE...
| Schlagworte: | PIM2, Pim-2h, EC=2.7.11.1, Serine/threonine-protein kinase pim-2, Recombinant Human Serine/threonine-protein kinase pim-2... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 41.7 kD |
ab 247,00 €
Anti-PIM2
Artikelnummer: CSB-PA438428.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PIM2. Antigen Species: Human
| Schlagworte: | Anti-PIM2, Anti-Pim-2h, EC=2.7.11.1, Anti-Serine/threonine-protein kinase pim-2, OTTHUMP00000025825 antibody, Pim 2... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Anti-PIM2
Artikelnummer: CSB-PA545216.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PIM2. Antigen Species: Human
| Schlagworte: | Anti-PIM2, Anti-Pim-2h, EC=2.7.11.1, Anti-Serine/threonine-protein kinase pim-2, OTTHUMP00000025825 antibody, Pim 2... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
AZD 1208
Artikelnummer: Cay20235-1
AZD 1208 is a potent, selective, and orally available inhibitor of all three forms of the proto-oncogene Pim kinase (IC50s = 0.4, 5.0, and 1.9 nM for Pim-1, Pim-2, and Pim-3, respectively). It causes cell cycle arrest and apoptosis in MOLM-16 megakaryoblastic leukemia cells and inhibits the growth of MOLM-16...
| Schlagworte: | (5Z)-[[2-[(3R)-3-amino-1-piperidinyl][1,1'-biphenyl]-3-yl]methylene]-2,4-thiazolidinedione |
| Anwendung: | Pim-1 / Pim-2 / Pim-3 inhibitor |
| CAS | 1204144-28-4 |
| MW: | 379.5 D |
ab 44,00 €
TP-3654
Artikelnummer: Cay29571-5
TP-3654 is an inhibitor of Pim kinases (Kis = 5, 239, and 42 nM for Pim-1, Pim-2, and Pim-3, respectively). It inhibits 19 additional kinases, including PI3Kalpha, PI3Kgamma, and PI3Kdelta, with IC50 values of less than 300 nM. TP-3654 inhibits phosphorylation of Bad in HEK293 cells overexpressing Bad and Pim-1...
| Schlagworte: | trans-alpha,alpha-dimethyl-4-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]-cyclohexanemethanol |
| Anwendung: | Pim kinase inhibitor |
| CAS | 1361951-15-6 |
| MW: | 418.5 D |
ab 78,00 €
AZD1208
Artikelnummer: SYN-1214-M005
Potent, highly selective and orally available Pim kinase inhibitor that effectively inhibits all three isoforms Pim-1, Pim-2 and Pim-3 at < 5nM or < 150 nM in enzyme and cell assays, respectively. Potently inhibits colony growth and Pim signalling substrates in primary AML cells from bone marrow that are Flt3...
| Schlagworte: | AZD-1208 |
| Anwendung: | Pim kinase inhibitor |
| CAS | 1204144-28-4 |
| MW: | 379,5 D |
ab 92,00 €
Anti-PIM2
Artikelnummer: NSJ-R34382-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Proto-oncogene Pim-2 (serine threonine kinase) Protein function: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic...
| Schlagworte: | Anti-PIM2, Anti-Pim-2h, EC=2.7.11.1, Anti-Serine/threonine-protein kinase pim-2, PIM2 Antibody |
| Anwendung: | WB (transfected), ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
790,00 €
Anti-PIM2
Artikelnummer: NSJ-R35096-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Serine/threonine protein kinase pim-2 Protein function: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity...
| Schlagworte: | Anti-PIM2, Anti-Pim-2h, EC=2.7.11.1, Anti-Serine/threonine-protein kinase pim-2, PIM2 Antibody |
| Anwendung: | WB (transfected), ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
790,00 €
Anti-PIM2
Artikelnummer: NSJ-R35489-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Serine/threonine-protein kinase pim-2 Protein function: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity...
| Schlagworte: | Anti-PIM2, Anti-Pim-2h, EC=2.7.11.1, Anti-Serine/threonine-protein kinase pim-2, PIM2 Antibody |
| Anwendung: | WB (transfected), ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
790,00 €
CX-6258
Artikelnummer: SYN-1182-M005
Soluble in DMSO. CX6258 is a potent inhibitor of Pim-1, Pim-2 and Pim-3 with IC(50) values of 5, 25 and 16nM, respectively. Target: PKC - PKC alpha, , Kinase Group: STE , Substrate: Serine-Threonine
| Schlagworte: | CX6258 |
| Anwendung: | Pim-1 / Pim-2 / Pim-3 inhibitor |
| CAS | 1202916-90-2 |
| MW: | 461,9 D |
ab 293,00 €
![5-[(4-Propyloxyphenyl)methylene] 2,4-thiazolidinedione](https://www.biomol.com/media/image/db/be/dd/CDX-P0110-M005_200x200.png "5-[(4-Propyloxyphenyl)methylene] 2,4-thiazolidinedione")
5-[(4-Propyloxyphenyl)methylene] 2,4-thiazolidinedione
Artikelnummer: CDX-P0110-M010
Yellow powder. Soluble in DMSO. Potent, cell-permeable, ATP-competitive inhibitor of Pim-1/2 kinases (IC50 = 150 nM and 20 nM against Pim-1 and Pim-2, respectively) as well as DYRK1alpha (68% inhibition of DYRK1alpha and Pim-2 at 5 µ,M), while exhibiting little or no activity against a panel of 57 other kinases...
| Schlagworte: | (Z)-5-(4-Propoxybenzylidene)thiazolidine-2,4-dione, SMI-16a |
| Anwendung: | Cell-permeable Pim-1/2 inhibitor |
| CAS | 587852-28-6 |
| MW: | 263,3 D |
ab 114,00 €
Anti-PIM2
Artikelnummer: ARG58172.100
Protein function: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression, the regulation of cap-dependent protein translation and through...
| Schlagworte: | Anti-PIM2, Anti-Pim-2h, EC=2.7.11.1, Anti-Serine/threonine-protein kinase pim-2 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
658,00 €