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Zu "K08557" wurden 324 Artikel gefunden!
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Artikelnummer: IB-IB03001
This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of full-length, unmodified human androgen receptor (NR3C4), a ligand-dependent transcription factor commonly referred to as AR. INDIGO's reporter cells include the luciferase...
Schlagworte: | AR, DHTR, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4 |
Anwendung: | Functional activity screening |
Spezies-Reaktivität: | human |
ab 1.507,00 €
NEU
Artikelnummer: Cay32986-1
Testosterone-d3 (Cay-32986) is an analytical reference standard intended for use as an internal standard for the quantification of testosterone (Cay-15645, Cay-ISO00154, Cay-ISO60154) by GC- or LC-MS. Testosterone is categorized as an anabolic androgenic steroid. It is an endogenous metabolite of androstenedione...
Schlagworte: | 17ß-hydroxy-androst-4-en-3-one-16,16,17-d3 |
Anwendung: | GC-MS, LC-MS internal standard, quantification, anabolic androgenic steroid |
CAS | 77546-39-5 |
MW: | 291.4 D |
210,00 €
NEU
Artikelnummer: A700-352
The androgen receptor (AR) functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes [taken from NCBI Entrez Gene (Gene ID:...
Schlagworte: | Anti-AR, Anti-DHTR, Anti-Androgen receptor, Anti-Dihydrotestosterone receptor, Anti-Nuclear receptor subfamily 3 group C... |
Anwendung: | WB, IP, IHC, ICC, FC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 185,00 €
NEU
Artikelnummer: A700-352CF
The androgen receptor (AR) functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes [taken from NCBI Entrez Gene (Gene ID:...
Schlagworte: | Anti-AR, Anti-DHTR, Anti-Androgen receptor, Anti-Dihydrotestosterone receptor, Anti-Nuclear receptor subfamily 3 group C... |
Anwendung: | WB, IP, IHC, ICC, FC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
1.156,00 €
Artikelnummer: CSB-EP001975HU4.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-400aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MEVQLGLGRV YPRPPSKTYR GAFQNLFQSV REVIQNPGPR HPEAASAAPP GASLLLLQQQ QQQQQQQQQQ QQQQQQQQQQ ETSPRQQQQQ QGEDGSPQAH RRGPTGYLVL...
Schlagworte: | AR, DHTR, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4 |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 49.7 kD |
ab 219,00 €
Artikelnummer: ABS-KC-2488.100
Protein function: Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits...
Schlagworte: | Anti-Androgen receptor, Anti-Dihydrotestosterone receptor, Anti-Nuclear receptor subfamily 3 group C member 4, AR Antibody |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
ab 232,00 €
Artikelnummer: Cay41670-1
Masofaniten is an androgen receptor N-terminal transactivation domain inhibitor (ARTADI). It binds to the tryptophan residues in positions 397 (W397) and W433 in the AR TAD.Formal Name: N-[4-[[4-[1-[3-chloro-4-(2-chloroethoxy)-5-cyanophenyl]-1-methylethyl]phenoxy]methyl]-2-pyrimidinyl]-methanesulfonamide. CAS...
Schlagworte: | EPI-7386,... |
Anwendung: | Androgen receptor N-terminal transactivation domain inhibitor (ARTADI) |
CAS | 2416716-62-4 |
MW: | 535.4 D |
ab 146,00 €
Artikelnummer: Cay42092-1
(S)-SKBG-1 is an inactive enantiomer of (R)-SKBG-1 (Cay-42091), a degrader of mRNA encoding the androgen receptor (AR).Formal Name: (2S)-4-(2-chloroacetyl)-N-[(4-methoxyphenyl)methyl]-1-[(4-methoxyphenyl)sulfonyl]-2-piperazinecarboxamide. CAS Number: 2955618-24-1. Molecular Formula: C22H26ClN3O6S. Formula Weight:...
Schlagworte: | (2S)-4-(2-chloroacetyl)-N-[(4-methoxyphenyl)methyl]-1-[(4-methoxyphenyl)sulfonyl]-2-piperazinecarboxamide |
Anwendung: | Inactive enantiomer |
CAS | 2955618-24-1 |
MW: | 496 D |
ab 239,00 €
Artikelnummer: Cay9002761-1
5alpha-dihydro-11-keto Testosterone-d3 is intended for use as an internal standard for the quantification of 5alpha-dihydro-11-keto testosterone (Cay-20200) by GC- or LC-MS. 5alpha-dihydro-11-keto Testosterone is a metabolite of 11beta-hydroxyandrostenedione and 11beta-hydroxytestosterone that has been shown to act...
Schlagworte: | 11-keto Dihydrotestosterone-d3, 17beta-hydroxy-5alpha-Androstane-3,11-dione-d3, 5alpha-Androstane-3,11-dione-17beta-ol-d3,... |
Anwendung: | Analytical reference standard, GC-MS, LC-MS internal standard, quantification, metabolite, AR agonist |
MW: | 307.4 D |
ab 100,00 €
Artikelnummer: TGM-T7690-100mg
Description: 2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR) for the treatment of prostate cancer. Target: Androgen Receptor. Smiles: CC(C)(O)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O. References: Blobaum A L , Byers F W , Bridges T M , et al. A Screen of Approved Drugs Identifies the Androgen...
Anwendung: | Antiandrogen, Chemopreventive agent |
CAS | 52806-53-8 |
MW: | 292.21 D |
ab 46,00 €
Artikelnummer: TGM-T72985-100mg
Description: Masofaniten (Androgen receptor-IN-2), a potent, orally active inhibitor of the androgen receptor, demonstrates significant antitumor activity against prostate cancer. Target: Others. Smiles: C(C)(C)(C1=CC(C#N)=C(OCCCl)C(Cl)=C1)C2=CC=C(OCC3=NC(NS(C)(=O)=O)=NC=C3)C=C2
Schlagworte: | Androgen receptor-IN-2 |
Anwendung: | Targets androgen receptor (AR, NR3C4) |
CAS | 2416716-62-4 |
MW: | 535.44 D |
ab 1.620,00 €
Artikelnummer: TGM-T8709-100mg
Description: Nandrolone phenylpropionate (Nandrolone phenpropionate) is an androgen receptor agonist. It mainly used to treat women with breast cancer and osteoporosis. Target: Androgen Receptor. Smiles: C[C@@]12[C@]([C@]3([C@@]([C@@]4(C(CC3)=CC(=O)CC4)[H])(CC1)[H])[H])(CC[C@@H]2OC(CCC5=CC=CC=C5)=O)[H]. References:...
Schlagworte: | Nandrolone phenpropionate |
Anwendung: | Targets androgen receptor (AR, NR3C4) |
CAS | 62-90-8 |
MW: | 406.56 D |
ab 38,00 €