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AR (human) Reporter Assay Kit
AR (human) Reporter Assay Kit

Artikelnummer: IB-IB03001

This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of full-length, unmodified human androgen receptor (NR3C4), a ligand-dependent transcription factor commonly referred to as AR. INDIGO's reporter cells include the luciferase...
Schlagworte: AR, DHTR, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4
Anwendung: Functional activity screening
Spezies-Reaktivität: human
ab 1.507,00 €
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NEU
Testosterone-d3
Testosterone-d3

Artikelnummer: Cay32986-1

Testosterone-d3 (Cay-32986) is an analytical reference standard intended for use as an internal standard for the quantification of testosterone (Cay-15645, Cay-ISO00154, Cay-ISO60154) by GC- or LC-MS. Testosterone is categorized as an anabolic androgenic steroid. It is an endogenous metabolite of androstenedione...
Schlagworte: 17ß-hydroxy-androst-4-en-3-one-16,16,17-d3
Anwendung: GC-MS, LC-MS internal standard, quantification, anabolic androgenic steroid
CAS 77546-39-5
MW: 291.4 D
210,00 €
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NEU
Anti-Androgen Receptor Recombinant Monoclonal
Anti-Androgen Receptor Recombinant Monoclonal

Artikelnummer: A700-352

The androgen receptor (AR) functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes [taken from NCBI Entrez Gene (Gene ID:...
Schlagworte: Anti-AR, Anti-DHTR, Anti-Androgen receptor, Anti-Dihydrotestosterone receptor, Anti-Nuclear receptor subfamily 3 group C...
Anwendung: WB, IP, IHC, ICC, FC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 185,00 €
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NEU
Anti-Androgen Receptor Recombinant Monoclonal
Anti-Androgen Receptor Recombinant Monoclonal

Artikelnummer: A700-352CF

The androgen receptor (AR) functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes [taken from NCBI Entrez Gene (Gene ID:...
Schlagworte: Anti-AR, Anti-DHTR, Anti-Androgen receptor, Anti-Dihydrotestosterone receptor, Anti-Nuclear receptor subfamily 3 group C...
Anwendung: WB, IP, IHC, ICC, FC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
1.156,00 €
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Androgen receptor (AR), partial, recombinant human
Androgen receptor (AR), partial, recombinant human

Artikelnummer: CSB-EP001975HU4.1

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-400aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MEVQLGLGRV YPRPPSKTYR GAFQNLFQSV REVIQNPGPR HPEAASAAPP GASLLLLQQQ QQQQQQQQQQ QQQQQQQQQQ ETSPRQQQQQ QGEDGSPQAH RRGPTGYLVL...
Schlagworte: AR, DHTR, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4
Anwendung: Activity not tested
Exprimiert in: E.coli
Ursprungsart: human
MW: 49.7 kD
ab 219,00 €
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Anti-AR
Anti-AR

Artikelnummer: ABS-KC-2488.100

Protein function: Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits...
Schlagworte: Anti-Androgen receptor, Anti-Dihydrotestosterone receptor, Anti-Nuclear receptor subfamily 3 group C member 4, AR Antibody
Wirt: Mouse
Spezies-Reaktivität: human
ab 232,00 €
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Masofaniten
Masofaniten

Artikelnummer: Cay41670-1

Masofaniten is an androgen receptor N-terminal transactivation domain inhibitor (ARTADI). It binds to the tryptophan residues in positions 397 (W397) and W433 in the AR TAD.Formal Name: N-[4-[[4-[1-[3-chloro-4-(2-chloroethoxy)-5-cyanophenyl]-1-methylethyl]phenoxy]methyl]-2-pyrimidinyl]-methanesulfonamide. CAS...
Schlagworte: EPI-7386,...
Anwendung: Androgen receptor N-terminal transactivation domain inhibitor (ARTADI)
CAS 2416716-62-4
MW: 535.4 D
ab 146,00 €
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(S)-SKBG-1
(S)-SKBG-1

Artikelnummer: Cay42092-1

(S)-SKBG-1 is an inactive enantiomer of (R)-SKBG-1 (Cay-42091), a degrader of mRNA encoding the androgen receptor (AR).Formal Name: (2S)-4-(2-chloroacetyl)-N-[(4-methoxyphenyl)methyl]-1-[(4-methoxyphenyl)sulfonyl]-2-piperazinecarboxamide. CAS Number: 2955618-24-1. Molecular Formula: C22H26ClN3O6S. Formula Weight:...
Schlagworte: (2S)-4-(2-chloroacetyl)-N-[(4-methoxyphenyl)methyl]-1-[(4-methoxyphenyl)sulfonyl]-2-piperazinecarboxamide
Anwendung: Inactive enantiomer
CAS 2955618-24-1
MW: 496 D
ab 239,00 €
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5alpha-dihydro-11-keto Testosterone-d3
5alpha-dihydro-11-keto Testosterone-d3

Artikelnummer: Cay9002761-1

5alpha-dihydro-11-keto Testosterone-d3 is intended for use as an internal standard for the quantification of 5alpha-dihydro-11-keto testosterone (Cay-20200) by GC- or LC-MS. 5alpha-dihydro-11-keto Testosterone is a metabolite of 11beta-hydroxyandrostenedione and 11beta-hydroxytestosterone that has been shown to act...
Schlagworte: 11-keto Dihydrotestosterone-d3, 17beta-hydroxy-5alpha-Androstane-3,11-dione-d3, 5alpha-Androstane-3,11-dione-17beta-ol-d3,...
Anwendung: Analytical reference standard, GC-MS, LC-MS internal standard, quantification, metabolite, AR agonist
MW: 307.4 D
ab 100,00 €
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2-hydroxy Flutamide
2-hydroxy Flutamide

Artikelnummer: TGM-T7690-100mg

Description: 2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR) for the treatment of prostate cancer. Target: Androgen Receptor. Smiles: CC(C)(O)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O. References: Blobaum A L , Byers F W , Bridges T M , et al. A Screen of Approved Drugs Identifies the Androgen...
Anwendung: Antiandrogen, Chemopreventive agent
CAS 52806-53-8
MW: 292.21 D
ab 46,00 €
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Masofaniten
Masofaniten

Artikelnummer: TGM-T72985-100mg

Description: Masofaniten (Androgen receptor-IN-2), a potent, orally active inhibitor of the androgen receptor, demonstrates significant antitumor activity against prostate cancer. Target: Others. Smiles: C(C)(C)(C1=CC(C#N)=C(OCCCl)C(Cl)=C1)C2=CC=C(OCC3=NC(NS(C)(=O)=O)=NC=C3)C=C2
Schlagworte: Androgen receptor-IN-2
Anwendung: Targets androgen receptor (AR, NR3C4)
CAS 2416716-62-4
MW: 535.44 D
ab 1.620,00 €
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Nandrolone phenylpropionate
Nandrolone phenylpropionate

Artikelnummer: TGM-T8709-100mg

Description: Nandrolone phenylpropionate (Nandrolone phenpropionate) is an androgen receptor agonist. It mainly used to treat women with breast cancer and osteoporosis. Target: Androgen Receptor. Smiles: C[C@@]12[C@]([C@]3([C@@]([C@@]4(C(CC3)=CC(=O)CC4)[H])(CC1)[H])[H])(CC[C@@H]2OC(CCC5=CC=CC=C5)=O)[H]. References:...
Schlagworte: Nandrolone phenpropionate
Anwendung: Targets androgen receptor (AR, NR3C4)
CAS 62-90-8
MW: 406.56 D
ab 38,00 €
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