Zu "K08555" wurden 70 Artikel gefunden!
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Desoxycorticosterone pivalate
Artikelnummer: TGM-TC0008-2mg
Description: Deoxycorticosterone (DOCP) is a mineralocorticoid and is an analog of deoxycorticosterone. Deoxycorticosterone pivalate is used in the treatment of canine low adrenal cortex hormones. Target: Others. Smiles: [H][C@@]12CC[C@H](C(=O)COC(=O)C(C)(C)C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C....
| Schlagworte: | DOCP |
| Anwendung: | Targets mineralocorticoid receptor (NR3C2, MR) |
| CAS | 808-48-0 |
| MW: | 414.58 D |
44,00 €
11Beta-hydroxyprogesterone
Artikelnummer: TGM-TCA2511-10mg
Description: 11Beta-hydroxyprogesterone (11beta-Hydroxyprogesterone) is an inhibitor of 11beta-hydroxysteroid dehydrogenase (11betaHSD) type 2, which activates the human hydrocorticosteroid receptor in COS-7 cells, and may be useful in the study of metabolism-related diseases. Target: Dehydrogenase. Smiles:...
| Schlagworte: | 11beta-Hydroxyprogesterone |
| Anwendung: | Progesterone metabolite, mineralocorticoid receptor agonist |
| CAS | 600-57-7 |
| MW: | 330.46 D |
ab 52,00 €
Corticosterone-d8
Artikelnummer: TGM-TMIH-0167-10mg
Description: Corticosterone-d8 is a deuterated compound of Corticosterone. Smiles: [2H]C1=C2C([2H])([2H])C[C@H]3[C@@H]4CC[C@]([2H])(C(=O)C([2H])([2H])O)[C@@]4(C)C[C@H](O)[C@@H]3[C@@]2(C)CC([2H])([2H])C1=O
| Anwendung: | GC-MS, LC-MS, internal standard, quantification, steroid hormone, mineralocorticoid receptor agonist |
| CAS | 1271728-07-4 |
| MW: | 354.51 D |
ab 126,00 €
Aldosterone-d8
Artikelnummer: TGM-T19185-100mg
Description: Aldosterone D8, a deuterium-labeled variant of Aldosterone produced in the adrenal zona glomerulosa, regulates blood pressure. Smiles: C(C(O)([2H])[2H])(=O)[C@@]1([C@]23[C@]([C@]4([C@]([C@H](C2)OC3O)([C@]5(C)C(C(C4)([2H])[2H])=C(C(=O)C(C5)([2H])[2H])[2H])[H])[H])(CC1)[H])[2H]. References: Azizan EA, et...
| Schlagworte: | Aldosterone D8 |
| Anwendung: | Steroid, LC/MS internal standard |
| CAS | 1261254-31-2 |
| MW: | 368.49 D |
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Aldosterone
Artikelnummer: TGM-T19186-2mg
Description: Aldosterone, the primary mineralocorticoid, is synthesized and secreted by the zona glomerulosa of the adrenal cortex in response to activation of the renin-angiotensin system or high dietary potassium. Target: Others. Smiles: C[C@]12CCC(=O)C=C1CC[C@H]1[C@@H]3CC[C@H](C(=O)CO)[C@]3(C[C@H](O)[C@H]21)C=O....
| Anwendung: | Targets mineralocorticoid receptor (NR3C2, MR) |
| CAS | 52-39-1 |
| MW: | 360.44 D |
329,00 €
Esaxerenone
Artikelnummer: Cay41082-10
Esaxerenone is a non-steroidal mineralocorticoid receptor antagonist (IC50 = 9.4 nM). It is selective for mineralocorticoid receptors over glucocorticoid, androgen, and progesterone receptors (IC50s = >10,000 nM for all). Esaxerenone (0.3, 1, or 3 mg/kg) increases the urinary ratio of sodium to potassium in...
| Schlagworte: | CS-3150, 1-(2-hydroxyethyl)-4-methyl-N-[4-(methylsulfonyl)phenyl]-5S-[2-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide |
| Anwendung: | Non-steroidal mineralocorticoid receptor antagonist |
| CAS | 1632006-28-0 |
| MW: | 466.5 D |
ab 181,00 €
Dicirenone
Artikelnummer: TGM-T13881-1mg
Description: Dicirenone (SC26304) inhibits the Mineralocorticoid receptor (MR), aldosterone regulation of the urinary K+:Na+ ratio, and aldosterone binding to renal cytoplasmic and nuclear receptors. Target: Glucocorticoid Receptor, ATPase. Smiles:...
| Schlagworte: | SC26304 |
| Anwendung: | Targets mineralocorticoid receptor (NR3C2, MR) |
| CAS | 41020-79-5 |
| MW: | 428.56 D |
ab 686,00 €
Esaxerenone
Artikelnummer: TGM-T15246-100mg
Description: Esaxerenone (XL-550) is a highly potent and selective non-steroidal antagonist of the mineralocorticoid receptor. Target: Glucocorticoid Receptor. Smiles: Cc1c(cn(CCO)c1-c1ccccc1C(F)(F)F)C(=O)Nc1ccc(cc1)S(C)(=O)=O. References: Yamada M, et al. Pharmacokinetics, distribution, and disposition of...
| Schlagworte: | CS-3150, XL-550 |
| Anwendung: | Targets mineralocorticoid receptor (NR3C2, MR) |
| CAS | 1632006-28-0 |
| MW: | 466.47 D |
ab 63,00 €
Fludrocortisone acetate
Artikelnummer: TGM-T1666-100mg
Description: Fludrocortisone acetate (9alpha-Fludrocortisone acetate), a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and initiates transcription of glucocorticoid-responsive genes like lipocortins to inhibit phospholipase A2 (PLA2). As the acetate salt of a synthetic...
| Schlagworte: | 9alpha-fluorocortisol acetate, 9alpha-Fluorcortisol acetate, 9alpha-Fludrocortisone acetate |
| Anwendung: | Targets mineralocorticoid receptor (NR3C2, MR) |
| CAS | 514-36-3 |
| MW: | 422.49 D |
30,00 €
Fludrocortisone
Artikelnummer: TGM-T1666L-100mg
Description: Fludrocortisone (Florinef) is a synthetic corticosteroid with moderate glucocorticoid potency and much greater mineralocorticoid potency. Fludrocortisone can be used to studies on treating low blood pressure. Target: Others. Smiles: C[C@]12C[C@H](O)C3(F)[C@@H](CCC4=CC(=O)CC[C@]34C)C1CCC2(O)C(=O)CO....
| Schlagworte: | 9alpha-Fluorcortisol, Florinef, 9alpha-fluorocortisol, 9alpha-Fludrocortisone, 9alpha-fluorohydrocortisone,... |
| Anwendung: | Targets mineralocorticoid receptor (NR3C2, MR) |
| CAS | 127-31-1 |
| MW: | 380.45 D |
ab 35,00 €
Finerenone
Artikelnummer: TGM-T21395-1mg
Description: Finerenone (BAY-948862) is a nonsteroidal antagonist of the mineralocorticoid receptor (MR) (IC50=18 nM) with selective and oral activity. Finerenone is used in the treatment of patients with chronic kidney disease with type 2 diabetes. Target: Glucocorticoid Receptor. Smiles:...
| Schlagworte: | BAY-948862, BAY948862, BAY94-8862, BAY 94-8862, BAY-94-8862, BAY 948862 |
| Anwendung: | Targets mineralocorticoid receptor (NR3C2, MR) |
| CAS | 1050477-31-0 |
| MW: | 378.42 D |
ab 32,00 €
Canrenoate potassium
Artikelnummer: TGM-T3096-100mg
Description: Canrenoate potassium (Soldactone) is a synthetic pregnadiene derivative with anti-aldosterone activity. Target: Glucocorticoid Receptor. Smiles: [K+].C(=O)(CC[C@@]1(CC[C@H]2[C@@H]3C=CC4=CC(=O)CC[C@@]4([C@H]3CC[C@]12C)C)O)[O-]. References: Alexandre J, et al. J Cardiovasc Pharmacol Ther. 2015...
| Schlagworte: | Soldactone, Potassium canrenoate, Canrenoic acid potassium salt, Potassium aldadiene |
| Anwendung: | Mineralocorticoid receptor antagonist |
| CAS | 2181-04-6 |
| MW: | 396.56 D |
30,00 €