Zu "K08552" wurden 39 Artikel gefunden!
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SLU-PP-332
Artikelnummer: Cay41719-10
SLU-PP-332 is an agonist of estrogen-related receptor alpha (ERRalpha), ERRbeta, and ERRgamma. It induces reporter gene expression in HEK293 cells expressing ERRalpha, ERRbeta, or ERRgamma (EC50s = 98, 230, and 430 nM, respectively). SLU-PP-332 (10 µM) increases mitochondrial respiration in C2C12 skeletal myoblasts....
| Schlagworte: | 4-hydroxy-benzoic acid, 2-(2-naphthalenylmethylene)hydrazide |
| Anwendung: | ERRalpha/beta/gamma agonist |
| CAS | 303760-60-3 |
| MW: | 290.3 D |
ab 54,00 €
GSK-4716
Artikelnummer: TGM-T5531-100mg
Description: GSK4716 is an ERRbeta/gamma agonist (IC50 = 2 µM) that can activate the receptor with similar potency as the protein ligand. Target: Estrogen Receptor/ERR. Smiles: CC(C)c1ccc(\C=N\NC(=O)c2ccc(O)cc2)cc1. References: Wang L , Zuercher W J , Consler T G , et al. X-ray Crystal Structures of the...
| Anwendung: | ERR beta/gamma agonist |
| CAS | 101574-65-6 |
| MW: | 282.34 D |
ab 40,00 €
ERR1 Protein, Human, Recombinant (GST)
Artikelnummer: TGM-TMPH-02142-100ug
Description: Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene...
| Schlagworte: | Nuclear receptor subfamily 3 group B member 1, Estrogen receptor-like 1, Estrogen-related receptor alpha, ESRRA, Steroid... |
| MW: | 72.5 kD |
ab 281,00 €
Steroid hormone receptor ERR1 (ESRRA), human, recombinant
Artikelnummer: CSB-EP007834HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-423aa. Protein Length: Full Length. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MSSQVVGIEP LYIKAEPASP DSPKGSSETE TEPPVALAPG PAPTRCLPGH KEEEDGEGAG PGEQGGGKLV LSSLPKRLCL VCGDVASGYH YGVASCEACK AFFKRTIQGS IEYSCPASNE CEITKRRRKA CQACRFTKCL...
| Schlagworte: | ERR1, ESRRA, ERR-alpha, Estrogen receptor-like 1, Steroid hormone receptor ERR1, Estrogen-related receptor alpha, Nuclear... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 72.5 kD |
ab 292,00 €
GSK4716
Artikelnummer: Cay17233-10
The estrogen-related receptors (ERRs) are orphan nuclear receptors with homology to the estrogen receptor family and are expressed in tissues with high metabolic demand. Binding of peroxisome proliferator-activated receptor gamma-coactivator 1alpha (PGC-1alpha) to this class of receptors is known to potentiate ERR...
| Schlagworte: | 4-hydroxy-2-[[4-(1-methylethyl)phenyl]methylene]hydrazide benzoic acid |
| Anwendung: | ERR beta/gamma agonist |
| CAS | 101574-65-6 |
| MW: | 282.3 D |
ab 55,00 €
Anti-ESRRA
Artikelnummer: ARG57416.100
Protein function: Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene...
| Schlagworte: | Anti-ERR1, Anti-ESRRA, Anti-ERR-alpha, Anti-Estrogen receptor-like 1, Anti-Steroid hormone receptor ERR1,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
658,00 €
ERRalpha (human) Reporter Assay Kit
Artikelnummer: IB-IB08002
This nuclear receptor assay system utilizes proprietary human mammalian cells engineered to provide high-level expression of a hybrid form of the human estrogen-related receptor alpha (NR3B1). The N-terminal DNA binding domains (DBD) of the native ERRalpha has been substituted with that of the yeast GAL4-DBD. The...
| Schlagworte: | ERR1, ESRRA, ERR-alpha, Estrogen receptor-like 1, Steroid hormone receptor ERR1, Estrogen-related receptor alpha, Nuclear... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
3.954,00 €
ERRalpha (human) Reporter Assay Kit
Artikelnummer: IB-IB08001
This nuclear receptor assay system utilizes proprietary human mammalian cells engineered to provide high-level expression of a hybrid form of the human estrogen-related receptor alpha (NR3B1). The N-terminal DNA binding domains (DBD) of the native ERRalpha has been substituted with that of the yeast GAL4-DBD. The...
| Schlagworte: | ERR1, ESRRA, ERR-alpha, Estrogen receptor-like 1, Steroid hormone receptor ERR1, Estrogen-related receptor alpha, Nuclear... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.507,00 €
XCT790
Artikelnummer: Cay16035-1
XCT790 is an inverse agonist of estrogen-related receptor alpha (ERRalpha, IC50 = ~300-500 nM). It demonstrates 90-100% inhibition of ERRalpha constitutive activity and has no significant activity at related nuclear receptors at 10 µM. XCT790 associates with the ligand-binding domain of ERRalpha and blocks...
| Schlagworte: | 3-[4-[[2,4-bis(trifluoromethyl)phenyl]methoxy]-3-methoxyphenyl]-2-cyano-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-2-pr... |
| Anwendung: | Inverse ERRalpha agonist |
| CAS | 725247-18-7 |
| MW: | 596.4 D |
ab 45,00 €
Anti-ESRRA
Artikelnummer: ATA-HPA053785.100
Protein function: Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium- chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene...
| Schlagworte: | Anti-ERR1, Anti-ESRRA, Anti-ERR-alpha, Anti-Estrogen receptor-like 1, Anti-Steroid hormone receptor ERR1,... |
| Anwendung: | ICC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 320,00 €
Mouse ERa (Estrogen Receptor Alpha) ELISA Kit
Artikelnummer: ELK-ELK2932.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse ERa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse ERa. Next,...
| Schlagworte: | Err1, Esrra, ERR-alpha, Estrogen receptor-like 1, Steroid hormone receptor ERR1, Estrogen-related receptor alpha, Nuclear... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 374,00 €
Human ERRa (Estrogen Related Receptor Alpha) ELISA Kit
Artikelnummer: ELK-ELK3342.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ERRa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ERRa. Next,...
| Schlagworte: | ERR1, ESRRA, ERR-alpha, Estrogen receptor-like 1, Steroid hormone receptor ERR1, Estrogen-related receptor alpha, Nuclear... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €