Zu "K08551" wurden 176 Artikel gefunden!
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Anti-ESR2
Artikelnummer: ATA-HPA068406.100
Polyclonal Antibody against Human ESR2, Gene description: estrogen receptor 2, Alternative Gene Names: ER-beta, Erb, NR3A2, Validated applications: ICC, WB, Uniprot ID: Q92731, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: Nuclear hormone receptor. Binds...
| Schlagworte: | Anti-ESR2, Anti-ESTRB, Anti-ER-beta, Anti-Estrogen receptor beta, Anti-Nuclear receptor subfamily 3 group A member 2 |
| Anwendung: | WB, ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
382,00 €
Tamoxifen
Artikelnummer: Cay13258-5
Tamoxifen is an estrogen receptor antagonist (IC50 = 45 nM for the rabbit receptor). It reduces the proliferation of MCF-7 breast cancer cells when used at a concentration of 10 µM. Tamoxifen is active against S. cerevisiae, C. neoformans, and five Candida species (MICs = 12, 64, and 8-64 µg/ml, respectively). It...
| Schlagworte: | 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-ethanamine |
| Anwendung: | Estrogen receptor modulator |
| CAS | 10540-29-1 |
| MW: | 371.5 D |
ab 78,00 €
Raloxifene
Artikelnummer: Cay41845-5
Raloxifene (Cay-41845) is an analytical reference standard categorized as a selective estrogen receptor modulator (SERM). It has been detected as an adverse analytical finding (AAF) during anti-doping testing. This product is intended for analytical forensic applications. This product is also available as a general...
| Schlagworte: | Keoxifene, LY156758, NSC 747974,... |
| Anwendung: | Analytical reference standard, selective estrogen receptor modulator (SERM) |
| CAS | 84449-90-1 |
| MW: | 473.6 D |
ab 150,00 €
(E/Z)-4-hydroxy Tamoxifen
Artikelnummer: Cay17308-50
(E/Z)-4-hydroxy Tamoxifen is an active metabolite of tamoxifen (Cay-13258). It is formed from tamoxifen by the cytochrome P450 (CYP) isoform CYP2D6. (E/Z)-4-hydroxy Tamoxifen is cytotoxic to MCF-7 and MDA-MB-231 breast cancer cells (IC50s = 27 and 18 µM, respectively). It also stimulates LC3 lipidation and the...
| Schlagworte: | 4-hydroxy Tamoxifen, 4-OHT, Afimoxifene, 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-phenol |
| Anwendung: | Active tamoxifen metabolite, estrogen receptor agonist/antagonist |
| CAS | 68392-35-8 |
| MW: | 387.5 D |
ab 44,00 €
Erteberel
Artikelnummer: TGM-T6306-10mg
Description: Erteberel (LY500307) is a potent, selective estrogen receptor beta agonist with EC50 of 0.66 nM, 32-fold selectivity against estrogen receptor alpha. Phase 2. Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor. Smiles: [H][C@]12CCC[C@@]1([H])c1cc(O)ccc1O[C@H]2c1ccc(O)cc1. References: Norman...
| Schlagworte: | LY500307 |
| Anwendung: | Targets estrogen receptor beta (ESR2, NR3A2) |
| CAS | 533884-09-2 |
| MW: | 282.33 D |
ab 156,00 €
Fulvestrant sulfone
Artikelnummer: TGM-T71710-10mg
Description: Fulvestrant sulfone is a synthetic estrogen receptor antagonist. Target: Others. Smiles: C(CCCCCCCCS(CCCC(C(F)(F)F)(F)F)(=O)=O)[C@H]1[C@@]2([C@@](C=3C(C1)=CC(O)=CC3)(CC[C@@]4(C)[C@]2(CC[C@@H]4O)[H])[H])[H]
| Anwendung: | Fulvestrant derivative, estrogen receptor antagonist |
| CAS | 98008-06-1 |
| MW: | 622.77 D |
ab 166,00 €
DPN
Artikelnummer: TGM-T7644-100mg
Description: DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor beta (ERbeta) . Target: Apoptosis, Autophagy, Estrogen Receptor/ERR, Estrogen/progestogen Receptor. Smiles: Oc1ccc(CC(C#N)c2ccc(O)cc2)cc1. References: Marvin, J, Meyers, et al. Estrogen Receptor-beta Potency-Selective Ligands:...
| Schlagworte: | Diarylpropionitrile |
| Anwendung: | ERbeta agonist |
| CAS | 1428-67-7 |
| MW: | 239.27 D |
ab 33,00 €
(E)-2-Decenoic acid
Artikelnummer: TGM-T7332-100mg
Description: (E)-2-Decenoic acid (trans-2-Decenoic acid) is an unsaturated fatty acid found in royal jelly produced from the hypopharyngeal and mandibular gland secretions of honeybees. Target: Others. Smiles: CCCCCCC\C=C\C(O)=O. References: Ramiro Vílchez, André Lemme, Ballhausen B , et al. Streptococcus mutans...
| Schlagworte: | trans-2-Decenoic acid |
| Anwendung: | Estrogen receptor beta 17beta-estradiol binding inhibitor |
| CAS | 334-49-6 |
| MW: | 170.25 D |
ab 34,00 €
ER beta Protein, Human, Recombinant (E. coli, His)
Artikelnummer: TGM-TMPH-01304-100ug
Description: Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner., Lacks ligand binding ability and has no or only very low ERE binding activity resulting in...
| Schlagworte: | Estrogen receptor beta, Nuclear receptor subfamily 3 group A member 2, ESR2 |
| MW: | 39.8 kD |
ab 198,00 €
ER beta Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-01305-100ug
Description: Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner., Lacks ligand binding ability and has no or only very low ERE binding activity resulting in...
| Schlagworte: | Nuclear receptor subfamily 3 group A member 2, ESR2, Estrogen receptor beta |
| MW: | 61.1 kD |
ab 229,00 €
(-)-(S)-Equol
Artikelnummer: TGM-T6491-100mg
Description: (-)-(S)-Equol (4',7-Dihydroxyisoflavan) is an orally bioavailable, non-steroidal estrogen naturally produced by the metabolism of the isoflavonoid daidzein by human intestinal microflora, with potential chemoprotective and estrogen receptor (ER) modulating activities. S-equol preferentially binds to and...
| Schlagworte: | 4',7-Isoflavandiol, Equol, 4',7-Dihydroxyisoflavan, (-)-Equol |
| Anwendung: | ERbeta agonist |
| CAS | 531-95-3 |
| MW: | 242.27 D |
ab 43,00 €
(E)-4-Hydroxytamoxifen
Artikelnummer: TGM-T15186-2mg
Description: (E)-4-Hydroxytamoxifen is a less active isomer of (Z)-4-hydroxytamoxifen and also is an estrogen receptor modulator. Target: Others. Smiles: C(=C(\CC)/C1=CC=CC=C1)(\C2=CC=C(OCCN(C)C)C=C2)/C3=CC=C(O)C=C3
| Anwendung: | Estrogen receptor 1 agonist/antagonist, estrogen receptor 2 agonist/antagonist |
| CAS | 174592-47-3 |
| MW: | 387.51 D |
81,00 €