- Suchergebnis für K08537
Cookie-Einstellungen
Diese Website benutzt Cookies, die für den technischen Betrieb der Website erforderlich sind und stets gesetzt werden. Andere Cookies, die den Komfort bei Benutzung dieser Website erhöhen, der Direktwerbung dienen oder die Interaktion mit anderen Websites und sozialen Netzwerken vereinfachen sollen, werden nur mit Ihrer Zustimmung gesetzt.
Konfiguration
Technisch erforderlich
Diese Cookies sind für die Grundfunktionen des Shops notwendig.
"Alle Cookies ablehnen" Cookie
"Alle Cookies annehmen" Cookie
Ausgewählter Shop
CSRF-Token
Cookie-Einstellungen
FACT-Finder Tracking
Individuelle Preise
Kundenspezifisches Caching
Session
Währungswechsel
Komfortfunktionen
Diese Cookies werden genutzt um das Einkaufserlebnis noch ansprechender zu gestalten, beispielsweise für die Wiedererkennung des Besuchers.
Facebook-Seite in der rechten Blog - Sidebar anzeigen
Merkzettel
Statistik & Tracking
Endgeräteerkennung
Kauf- und Surfverhalten mit Google Tag Manager
Partnerprogramm
Zu "K08537" wurden 57 Artikel gefunden!
Filter schließen
Filtern nach:
Für die Filterung wurden keine Ergebnisse gefunden!
Artikelnummer: ELK-ELK6978.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat FXR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat FXR. Next, Avidin...
Schlagworte: | Bar, Nr1h4, Bile acid receptor, Farnesol receptor HRR-1, RXR-interacting protein 14, Farnesoid X-activated receptor,... |
Anwendung: | ELISA |
Spezies-Reaktivität: | rat |
ab 365,00 €
Artikelnummer: Cay20289-500
Tauro-beta-muricholic acid (TbetaMCA) is a competitive and reversible antagonist of the farnesoid X receptor (FXR, IC50 = 40 µM) and a taurine-conjugated form of the murine-specific primary bile acid beta-muricholic acid (Cay-20287). TbetaMCA accumulates in germ-free mice under normal conditions but is reduced after...
Schlagworte: | Tauro-beta-muricholate, TbetaMCA, 2-[[(3alpha,5beta,6beta,7beta)-3,6,7-trihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic... |
Anwendung: | FXR antagonist |
CAS | 145022-92-0 |
MW: | 537.7 D |
ab 97,00 €
Artikelnummer: Cay10011286-1
Chenodeoxycholic acid (CDCA) is a hydrophobic primary bile acid. It is formed from cholesterol in the liver via a multistep process catalyzed by the cytochrome P450 (CYP) isoforms CYP7A1, CYP8B1, and CYP27A1. CDCA is a farnesoid X receptor (FXR) agonist that binds to FXRs in a TR-FRET assay (EC50 = 13 µM) and...
Schlagworte: | Anthropodeoxycholic Acid, CDCA, Fluibil, Hekbilin, Kebilis, Ulmenide, (3alpha,5beta,7alpha)-3,7-dihydroxy-cholan-24-oic acid |
Anwendung: | Bioactive lipid assays |
CAS | 474-25-9 |
MW: | 392.6 D |
ab 43,00 €
Artikelnummer: AG-CR1-3560-M005
Potent and selective farnesoid X receptor FXR agonist (EC50= 99nM) [1]. Induces SHP in HSCs to suppress TIMP-1 expression [2]. Apoptosis inducer [2]. Protects against liver fibrosis development in rat in vivo [2]. Displays anticholeretic activity in rat in vivo [3]. Promotes preadipocyte differentiation [4]....
Schlagworte: | 6alpha-Ethyl-chenodeoxycholic acid, 6-alpha-ECDC, Obeticholic acid, INT-747, OCA |
Anwendung: | FXR agonist |
CAS | 459789-99-2 |
MW: | 420,3 D |
ab 66,00 €
Artikelnummer: Cay20288-1
Tauro-alpha-muricholic acid (TalphaMCA) is an antagonist of the farnesoid X receptor (FXR, IC50 = 28 µM) and a taurine-conjugated form of the murine-specific primary bile acid alpha-muricholic acid (Cay-20291). TalphaMCA is common in rodents but has also been found in small amounts in human serum.Formal Name:...
Schlagworte: | Tauro-alpha-muricholate, TalphaMCA,... |
Anwendung: | Farnesoid X receptor (FXR) antagonist |
CAS | 2260905-08-4 |
MW: | 537.7 D |
212,00 €
Artikelnummer: Cay10006611-5
Farnesoid X receptor (FXR) is a nuclear receptor that acts as a bile acid sensor, protecting cells and organs against bile acid toxicity. GW 4064 is a selective agonist of FXR (EC50 = 15 nM). It displays no activity at other nuclear receptors, including the retinoic acid receptor, at concentrations up to 1 µM. GW...
Schlagworte: | 3-[2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methoxy]phenyl]ethenyl]-benzoic acid |
Anwendung: | FXR agonist |
CAS | 278779-30-9 |
MW: | 542.8 D |
ab 43,00 €
Artikelnummer: Cay9003230-10
Glycine-beta-muricholic acid (GbetaMCA) is an intestine-selective antagonist of the farnesoid X receptor (FXR) and the glycine-conjugated form of the murine-specific primary bile acid beta-muricholic acid (Cay-20287). It inhibits expression of the FXR target genes Shp and Fgf15 induced by the FXR ligands...
Schlagworte: | Gly-MCA, GbetaMCA, N-[(3alpha,5beta,6beta,7beta)-3,6,7-trihydroxy-24-oxocholan-24-yl]-glycine |
Anwendung: | FXR antagonist |
CAS | 66225-78-3 |
MW: | 465.6 D |
ab 158,00 €
Artikelnummer: Cay20848-1
Chenodeoxycholic acid-d4 (CDCA-d4) is intended for use as an internal standard for the quantification of CDCA (Cay-10011286) by GC- or LC-MS. CDCA is a hydrophobic primary bile acid. It is formed from cholesterol in the liver via a multistep process catalyzed by the cytochrome P450 (CYP) isoforms CYP7A1, CYP8B1, and...
Schlagworte: | CDCA-d4, 3alpha,7alpha-dihydroxy-5beta-cholan-24-oic-2,2,4,4-d4 acid |
Anwendung: | GC-MS, LC-MS, Internal standard, CDCA quantification |
CAS | 99102-69-9 |
MW: | 396.6 D |
ab 60,00 €
Artikelnummer: Cay38878-1
Tauro-obeticholic acid is an active metabolite of obeticholic acid, which is a farnesoid X receptor (FXR) agonist and semisynthetic derivative of chenodeoxycholic acid (Cay-10011286). Tauro-obeticholic acid is formed from obeticholic acid by taurine conjugation in the liver but can be reconverted back to obeticholic...
Schlagworte: | Obeticholic Acid Taurine Conjugate, Tauro-6-Ethyl-CDCA, Tauro-6-Ethylchenodeoxycholic Acid, Tauro-OCA, T-ECDCA,... |
Anwendung: | Obeticholic acid active metabolite, choleretic |
CAS | 2278141-79-8 |
MW: | 549.7 D |
ab 218,00 €
Artikelnummer: AG-CN2-0412-G001
White to off-white solid. Soluble in DMSO, ethanol or dimethylformamide. Sparingly soluble in water. Anti-hypercholestrolemic compound, Anti-inflammatory and immune-modulating effects, Anticancer compound. Chemopreventive, Cytostatic. Cell growth inhibitor, Antimutagenic, Potent in vitro antagonist of FXR (farnesoid...
Schlagworte: | Stigmasterin, Phytosterol, beta-Stigmasterol, Serposterol, Wulzen anti-stiffness Factor, NSC8095 |
Anwendung: | Chemopreventive compound |
CAS | 83-48-7 |
MW: | 412,7 D |
ab 44,00 €
Artikelnummer: IB-IB00601-32
This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of human farnesoid X receptor (NR1H4), a ligand-dependent transcription factor commonly referred to as FXR. INDIGO's reporter cells include the luciferase reporter gene...
Schlagworte: | BAR, NR1H4, Bile acid receptor, Farnesol receptor HRR-1, RXR-interacting protein 14, Farnesoid X-activated receptor,... |
Anwendung: | Functional activity screening |
Spezies-Reaktivität: | human |
ab 1.448,00 €
Artikelnummer: Cay23350-5
XL335 is an orally bioavailable and potent agonist of the farnesoid X receptor (FXR) with an EC50 value of 4 nM in CV-1 cells transfected with human FXR. It is selective for FXR over a panel of 15 nuclear receptors at concentrations up to 10 µM. XL335 induces expression of mouse intestinal bile acid binding protein...
Schlagworte: | FXR 450, Turofexorate Isopropyl, WAY-362450,... |
Anwendung: | FXR agonist |
CAS | 629664-81-9 |
MW: | 438.5 D |
ab 130,00 €