Zu "K08534" wurden 68 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
RORgamma (human) Reporter Assay Kit
Artikelnummer: IB-IB04001
This human RAR-related orphan receptor gamma (RORgamma) mRNA is expressed from the RORC gene in two forms via alternate usage of tissue-specific promoters. Variant 1 mRNA is expressed in numerous tissues, and encodes receptor isoform 1, referred to as RORgamma. Variant 2 mRNA comprises an alternate exon 1 that...
| Schlagworte: | RORC, NR1F3, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, RAR-related orphan receptor C, Retinoid-related... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.448,00 €
Nuclear receptor ROR-gamma (RORC), human, recombinant
Artikelnummer: CSB-EP020071HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-518aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: MDRAPQRQHR ASRELLAAKK THTSQIEVIP CKICGDKSSG IHYGVITCEG CKGFFRRSQR CNAAYSCTRQ QNCPIDRTSR NRCQHCRLQK CLALGMSRDA VKFGRMSKKQ RDSLHAEVQK QLQQRQQQQQ...
| Schlagworte: | RORC, NR1F3, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, RAR-related orphan receptor C, Retinoid-related... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 74.2 kD |
ab 213,00 €
Nuclear receptor ROR-gamma (Rorc), mouse, recombinant
Artikelnummer: CSB-YP020071MO.1
Organism: Mus musculus (Mouse). Source: Yeast. Expression Region: 1-516aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MDRAPQRHHR TSRELLAAKK THTSQIEVIP CKICGDKSSG IHYGVITCEG CKGFFRRSQQ CNVAYSCTRQ QNCPIDRTSR NRCQHCRLQK CLALGMSRDA VKFGRMSKKQ RDSLHAEVQK QLQQQQQQEQ VAKTPPAGSR...
| Schlagworte: | TOR, Rorc, Nr1f3, Thymus orphan receptor, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, RAR-related orphan... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | mouse |
| MW: | 60.1 kD |
ab 336,00 €
Anti-RORC
Artikelnummer: CSB-PA004023.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-RORC, Anti-NR1F3, Anti-Nuclear receptor ROR-gamma, Anti-Nuclear receptor RZR-gamma, Anti-RAR-related orphan receptor... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
106,00 €
Anti-RORC
Artikelnummer: CSB-PA439853.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-RORC, Anti-NR1F3, Anti-Nuclear receptor ROR-gamma, Anti-Nuclear receptor RZR-gamma, Anti-RAR-related orphan receptor... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
275,00 €
Anti-RORC / ROR gamma
Artikelnummer: NSJ-RQ7200
0.5mg/ml if reconstituted with 0.2ml sterile DI water. RAR-related orphan receptor gamma (RORg) is a protein that in humans is encoded by the RORC (RAR-related orphan receptor C) gene. The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone...
| Schlagworte: | Anti-RORC, Anti-NR1F3, Anti-Nuclear receptor ROR-gamma, Anti-Nuclear receptor RZR-gamma, Anti-RAR-related orphan receptor... |
| Anwendung: | WB, FC, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
755,00 €
GSK2981278
Artikelnummer: Cay20974-25
GSK2981278 is an inverse agonist of retinoic acid receptor-related nuclear receptor gamma (RORgamma, IC50 = 17 nM in a transactivation assay). It is selective for RORgamma over RORalpha. GSK2981278 inhibits IL-17A and IL-22 protein secretion from isolated human peripheral blood T cells grown under Th17 skewing...
| Schlagworte: | N-(4-ethylphenyl)-3-(hydroxymethyl)-N-(2-methylpropyl)-4-[(tetrahydro-2H-pyran-4-yl)methoxy]-benzenesulfonamide |
| Anwendung: | Potent, selective ROR gamma inverse agonist |
| CAS | 1474110-21-8 |
| MW: | 461.6 D |
ab 50,00 €
Human RORg (RAR Related Orphan Receptor Gamma) ELISA Kit
Artikelnummer: ELK-ELK4344.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human RORg. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human RORg. Next,...
| Schlagworte: | RORC, NR1F3, Nuclear receptor RZR-gamma, Nuclear receptor ROR-gamma, RAR-related orphan receptor C, Retinoid-related... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
SR 2211
Artikelnummer: Cay11972-1
Retinoic acid receptor-related nuclear receptor gamma (RORgamma) plays a central role in T cell differentiation, particularly in the differentiation of pro-inflammatory TH17 cells, which are implicated in autoimmune diseases like multiple sclerosis and rheumatoid arthritis. SR 2211 selectively binds RORgamma (Ki =...
| Schlagworte: | 2-fluoro-4'-[[4-(4-pyridinylmethyl)-1-piperazinyl]methyl]-alpha,alpha-bis(trifluoromethyl)-[1,1'-biphenyl]-4-methanol |
| Anwendung: | ROR gamma agonist |
| CAS | 1359164-11-6 |
| MW: | 527.5 D |
ab 50,00 €
SR 1001
Artikelnummer: Cay10922-1
Retinoic-acid-receptor-related orphan receptors (ROR) alpha and gamma play a key role in the development of T-helper cells that produce interleukin-17 (TH17 cells), a subset of CD4+ T-cells that contribute to the inflammatory process and have been implicated in the pathology of autoimmune diseases. SR 1001 is a...
| Schlagworte: | N-(5-(N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)sulfamoyl)-4-methylthiazol-2-yl)acetamide |
| Anwendung: | RORalpha and RORgamma inverse agonist |
| CAS | 1335106-03-0 |
| MW: | 477.4 D |
ab 43,00 €
SR1001
Artikelnummer: LKT-S6800.5
RORalpha/gamma inverse agonist.
| Anwendung: | RORalpha/gamma inverse agonist |
| CAS | 1335106-03-0 |
| MW: | 477.4 D |
ab 82,00 €
SR 0987
Artikelnummer: Cay19503-1
SR 0987 is an agonist of the T cell-specific isoform of RORgamma (RORgammat, retinoic acid receptor-related orphan receptor-gammat), inducing reporter gene expression with an EC50 value of ~800 nM. Stimulation of mouse EL4 T lymphocytes with SR 0987, following activation with PMA (Cay-10008014) and ionomycin...
| Schlagworte: | 2-chloro-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzamide |
| Anwendung: | RORgammat agonist |
| CAS | 303126-97-8 |
| MW: | 397.7 D |
ab 34,00 €