Zu "K08530" wurden 230 Artikel gefunden!
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Rosiglitazone
Artikelnummer: Cay71740-10
Rosiglitazone is an agonist of peroxisome proliferator-activated receptor gamma (PPARgamma). It activates PPARgamma1 and PPARgamma2 in reporter assays (EC50s = 30 and 100 nM, respectively). Rosiglitazone selectively activates chimeras containing the ligand-binding domains (LBDs) of PPARgamma over PPARalpha and...
| Schlagworte: | BRL 49653, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione |
| Anwendung: | PPARgamma agonist |
| CAS | 122320-73-4 |
| MW: | 357.4 D |
ab 43,00 €
NEU
FX-909
Artikelnummer: Cay41452-1
FX-909 is a peroxisome proliferator-activated receptor gamma (PPARgamma) inverse agonist. It inhibits the growth of urothelial cancer cells in vitro.Formal Name: 3-(5,7-difluoro-1,4-dihydro-4-oxo-2-quinolinyl)-4-(methylsulfonyl)-benzonitrile. CAS Number: 2924573-90-8. Molecular Formula: C17H10F2N2O3S. Formula...
| Schlagworte: | 3-(5,7-difluoro-1,4-dihydro-4-oxo-2-quinolinyl)-4-(methylsulfonyl)-benzonitrile |
| Anwendung: | PPARgamma inverse agonist |
| CAS | 2924573-90-8 |
| MW: | 360.3 D |
ab 108,00 €
NEU
BAY-0069
Artikelnummer: Cay41525-10
BAY-0069 is a peroxisome proliferator-activated receptor gamma (PPARgamma) inverse agonist. It acts as an inverse agonist in a co-repressor reporter assay with a peptide from nuclear receptor co-repressor 2 (NCOR2, EC50 = 9.6 nM). BAY-0069 selectively induces PPARgamma- over PPARalpha- or PPARdelta-mediated gene...
| Schlagworte: | 2-bromo-N-[2-(4-ethylphenyl)-5-benzoxazolyl]-5-nitro-benzamide |
| Anwendung: | PPARgamma inverse agonist |
| CAS | 420826-65-9 |
| MW: | 466.3 D |
ab 90,00 €
GW 9662
Artikelnummer: Cay70785-10
The peroxisome proliferator-activated receptor gamma (PPARgamma) is the nuclear receptor responsible for transducing the therapeutic activity of the thiazolidinediones. Thiazolidinediones are a group of structurally related synthetic PPARgamma agonists with antidiabetic actions in vivo. Rosiglitazone (BRL 49653) is...
| Schlagworte: | 2-chloro-5-nitrobenzanilide |
| Anwendung: | Irreversible PPARgamma antagonist |
| CAS | 22978-25-2 |
| MW: | 276.7 D |
ab 16,00 €
Lobeglitazone
Artikelnummer: TGM-T69011-100mg
Description: Lobeglitazone, also known as CKD-501, is an antidiabetic drug in the thiazolidinedione class of drugs. As an agonist for both PPARalpha and PPARgamma, it works as an insulin sensitizer by binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Target: Others. Smiles:...
| Anwendung: | Targets peroxisome proliferator-activated receptor gamma (NR1C3, PPARG) |
| CAS | 607723-33-1 |
| MW: | 480.54 D |
ab 1.491,00 €
Oleuropein
Artikelnummer: TGM-T6917-100mg
Description: Oleuropein is an antioxidant polyphenol isolated from olive leaf. Target: ROS, Apoptosis, PPAR, Aromatase. Smiles: COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)\C(=C\C)[C@@H]1CC(=O)OCCc1ccc(O)c(O)c1. References: Visioli F, et al. Life Sci. 1998,62(6), 541-546.
| Anwendung: | Antioxidant, free radical-scavenger, PPAR gamma antagonist |
| CAS | 32619-42-4 |
| MW: | 540.51 D |
ab 43,00 €
Punicic acid
Artikelnummer: TGM-T78472-10mg
Description: Punicic acid, a conjugated isomer of alpha-linolenic acid and a omega-5 polyunsaturated fatty acid found in pomegranate seed oil, holds potential for research into various chronic diseases [1]. Target: Others. Smiles: C(C/C=C\C=C\C=C/CCCC)CCCCCC(O)=O
| Schlagworte: | Trichosanic acid |
| Anwendung: | omega-5 long-chain PUFA, PPARgamma ligand |
| CAS | 544-72-9 |
| MW: | 278.43 D |
ab 193,00 €
Mavodelpar
Artikelnummer: TGM-T73088-100mg
Description: Mavodelpar (REN001), a selective PPARdelta agonist, effectively suppresses glomerular injury and renal fibrosis. It is utilized in the research of primary mitochondrial myopathies (PMM) and long-chain fatty acid oxidation disorders (LC-FAOD). Target: Others. Smiles:...
| Schlagworte: | REN001 , HPP593, HPP593, REN001 |
| Anwendung: | Targets peroxisome proliferator-activated receptor gamma (NR1C3, PPARG) |
| CAS | 1604815-32-8 |
| MW: | 537.55 D |
ab 1.638,00 €
NPC 15199
Artikelnummer: TGM-T8638-500mg
Description: NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent. Target: Others. Smiles: CC(C)C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O. References: Jan C R , Yu C C , Huang J K . NPC-15199, a novel anti-inflammatory agent, mobilizes intracellular Ca2+ in bladder female transitional carcinoma (BFTC) cells[J]....
| Schlagworte: | FMOC-L-Leucine |
| Anwendung: | PPARgamma modulator |
| CAS | 35661-60-0 |
| MW: | 353.41 D |
30,00 €
10,13-epoxy-11-methyl-Octadecadienoic Acid
Artikelnummer: TGM-T85012-10mg
Target: Others. Smiles: C(CCCCCCCC(O)=O)C=1OC(CCCCC)=CC1C
| Schlagworte: | F2 Furan Fatty Acid |
| Anwendung: | Furan fatty acid, PPARG agonist |
| CAS | 57818-39-0 |
| MW: | 308.5 D |
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PPAR gamma Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPH-02827-100ug
Description: PPAR gamma Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 63.3 kDa and the accession number is P37238.
| Schlagworte: | Nuclear receptor subfamily 1 group C member 3, Peroxisome proliferator-activated receptor gamma, Pparg |
| MW: | 63.3 kD |
ab 278,00 €
PPAR gamma Protein, Xenopus laevis, Recombinant (His)
Artikelnummer: TGM-TMPH-03711-100ug
Description: Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids....
| Schlagworte: | pparg, Peroxisome proliferator-activated receptor gamma, Nuclear receptor subfamily 1 group C member 3 |
| MW: | 58.1 kD |
ab 352,00 €