Zu "K08530" wurden 221 Artikel gefunden!
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Rosiglitazone
Artikelnummer: Cay71740-10
Rosiglitazone is an agonist of peroxisome proliferator-activated receptor gamma (PPARgamma). It activates PPARgamma1 and PPARgamma2 in reporter assays (EC50s = 30 and 100 nM, respectively). Rosiglitazone selectively activates chimeras containing the ligand-binding domains (LBDs) of PPARgamma over PPARalpha and...
| Schlagworte: | BRL 49653, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione |
| Anwendung: | PPARgamma agonist |
| CAS | 122320-73-4 |
| MW: | 357.4 D |
ab 44,00 €
GW 9662
Artikelnummer: Cay70785-10
The peroxisome proliferator-activated receptor gamma (PPARgamma) is the nuclear receptor responsible for transducing the therapeutic activity of the thiazolidinediones. Thiazolidinediones are a group of structurally related synthetic PPARgamma agonists with antidiabetic actions in vivo. Rosiglitazone (BRL 49653) is...
| Schlagworte: | 2-chloro-5-nitrobenzanilide |
| Anwendung: | Irreversible PPARgamma antagonist |
| CAS | 22978-25-2 |
| MW: | 276.7 D |
ab 16,00 €
FX-909
Artikelnummer: Cay41452-1
FX-909 is a peroxisome proliferator-activated receptor gamma (PPARgamma) inverse agonist. It inhibits the growth of urothelial cancer cells in vitro.Formal Name: 3-(5,7-difluoro-1,4-dihydro-4-oxo-2-quinolinyl)-4-(methylsulfonyl)-benzonitrile. CAS Number: 2924573-90-8. Molecular Formula: C17H10F2N2O3S. Formula...
| Schlagworte: | 3-(5,7-difluoro-1,4-dihydro-4-oxo-2-quinolinyl)-4-(methylsulfonyl)-benzonitrile |
| Anwendung: | PPARgamma inverse agonist |
| CAS | 2924573-90-8 |
| MW: | 360.3 D |
ab 108,00 €
BAY-0069
Artikelnummer: Cay41525-10
BAY-0069 is a peroxisome proliferator-activated receptor gamma (PPARgamma) inverse agonist. It acts as an inverse agonist in a co-repressor reporter assay with a peptide from nuclear receptor co-repressor 2 (NCOR2, EC50 = 9.6 nM). BAY-0069 selectively induces PPARgamma- over PPARalpha- or PPARdelta-mediated gene...
| Schlagworte: | 2-bromo-N-[2-(4-ethylphenyl)-5-benzoxazolyl]-5-nitro-benzamide |
| Anwendung: | PPARgamma inverse agonist |
| CAS | 420826-65-9 |
| MW: | 466.3 D |
ab 90,00 €
Troglitazone
Artikelnummer: Cay71750-5
Troglitazone is a selective agonist of peroxisome proliferator-activated receptor gamma (PPARgamma, EC50s = 0.78 and 0.55 µM for the mouse and human receptors, respectively, in a transactivation assay). It is selective for PPARgamma over PPARalpha and PPARdelta, at which it is inactive at concentrations up to 10 µM....
| Schlagworte: | 5-[[4-[(3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]-2,4-thiazolidinedione |
| Anwendung: | PPARgamma agonist |
| CAS | 97322-87-7 |
| MW: | 441.5 D |
ab 82,00 €
Punicic acid
Artikelnummer: TGM-T78472-10mg
Description: Punicic acid, a conjugated isomer of alpha-linolenic acid and a omega-5 polyunsaturated fatty acid found in pomegranate seed oil, holds potential for research into various chronic diseases [1]. Target: Others. Smiles: C(C/C=C\C=C\C=C/CCCC)CCCCCC(O)=O
| Schlagworte: | Trichosanic acid |
| Anwendung: | omega-5 long-chain PUFA, PPARgamma ligand |
| CAS | 544-72-9 |
| MW: | 278.43 D |
ab 198,00 €
Mavodelpar
Artikelnummer: TGM-T73088-100mg
Description: Mavodelpar (REN001), a selective PPARdelta agonist, effectively suppresses glomerular injury and renal fibrosis. It is utilized in the research of primary mitochondrial myopathies (PMM) and long-chain fatty acid oxidation disorders (LC-FAOD). Target: Others. Smiles:...
| Schlagworte: | REN001 , HPP593, HPP593, REN001 |
| Anwendung: | Targets peroxisome proliferator-activated receptor gamma (NR1C3, PPARG) |
| CAS | 1604815-32-8 |
| MW: | 537.55 D |
ab 1.671,00 €
NPC 15199
Artikelnummer: TGM-T8638-500mg
Description: NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent. Target: Others. Smiles: CC(C)C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O. References: Jan C R , Yu C C , Huang J K . NPC-15199, a novel anti-inflammatory agent, mobilizes intracellular Ca2+ in bladder female transitional carcinoma (BFTC) cells[J]....
| Schlagworte: | FMOC-L-Leucine |
| Anwendung: | PPARgamma modulator |
| CAS | 35661-60-0 |
| MW: | 353.41 D |
30,00 €
10,13-epoxy-11-methyl-Octadecadienoic Acid
Artikelnummer: TGM-T85012-10mg
Target: Others. Smiles: C(CCCCCCCC(O)=O)C=1OC(CCCCC)=CC1C
| Schlagworte: | F2 Furan Fatty Acid |
| Anwendung: | Furan fatty acid, PPARG agonist |
| CAS | 57818-39-0 |
| MW: | 308.5 D |
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PPAR gamma Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPH-02827-100ug
Description: PPAR gamma Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 63.3 kDa and the accession number is P37238.
| Schlagworte: | Nuclear receptor subfamily 1 group C member 3, Peroxisome proliferator-activated receptor gamma, Pparg |
| MW: | 63.3 kD |
ab 281,00 €
PPAR gamma Protein, Xenopus laevis, Recombinant (His)
Artikelnummer: TGM-TMPH-03711-100ug
Description: Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids....
| Schlagworte: | pparg, Peroxisome proliferator-activated receptor gamma, Nuclear receptor subfamily 1 group C member 3 |
| MW: | 58.1 kD |
ab 359,00 €
PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)
Artikelnummer: TGM-TMPY-02575-100ug
Description: Peroxisome proliferator-activated receptor gamma (PPARG), a nuclear hormone receptor, plays a critical role in the lipid and glucose homeostasis, adipocyte differentiation, as well as intracellular insulin-signaling events. The peroxisome proliferator-activated receptor gamma (PPARgamma) regulates...
| Schlagworte: | PPARgamma, CIMT1, PPARG1, PPARgamma, NR1C3, PPARG2, GLM1, peroxisome proliferator-activated receptor gamma, peroxisome... |
| MW: | 85.4 kD |
ab 385,00 €