Zu "K08527" wurden 87 Artikel gefunden!
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9-cis-Retinoic Acid
Artikelnummer: TGM-T21497-2mg
Description: 9-cis-Retinoic Acid (Alitretinoin) is a derivative of vitamin A. It is a RAR/RXR agonist with anticancer, antitumor, anti-inflammatory, and neuroprotective activities, induces apoptosis, regulates the cell cycle, and can be used to study advanced tumors. Target: Apoptosis. Smiles:...
| Schlagworte: | Alitretinoin |
| Anwendung: | RAR and RXR activator |
| CAS | 5300-03-8 |
| MW: | 300.44 D |
ab 77,00 €
Ro 41-5253
Artikelnummer: TGM-T28589-1mg
Description: Ro 41-5253 is an orally active RARalpha antagonist, ligand, and partial agonist of peroxisome proliferator-activated receptor (PPAR)-gamma. It exhibits antitumor activity, inhibits proliferation, and induces apoptosis in MCF-7 and ZR-75.1 estrogen receptor-positive breast cancer cells. Target:...
| Schlagworte: | Ro 415253, Ro-41-5253 |
| Anwendung: | RAR alpha antagonist |
| CAS | 144092-31-9 |
| MW: | 484.65 D |
52,00 €
all-trans-5,6-epoxy Retinoic Acid
Artikelnummer: TGM-T36382-1mg
Description: all-trans-5,6-Epoxy Retinoic Acid (Product No. T36382, CAS No. 13100-69-1) is utilized in life sciences research. Target: Others. Smiles: C(=C/C(=C/C=C/C(=C/C(O)=O)/C)/C)\C12C(C)(O1)CCCC2(C)C
| Anwendung: | RAR agonist |
| CAS | 13100-69-1 |
| MW: | 316.43 D |
ab 450,00 €
4-Oxoisotretinoin
Artikelnummer: TGM-T3559-100mg
Description: 4-Oxoisotretinoin (Ro 22-6595) is the major blood metabolite. Target: Others. Smiles: C(=C/C(=C/C=C/C(=C\C(O)=O)/C)/C)\C=1C(C)(C)CCC(=O)C1C. References: Lucio Vilar,et al. The Role of Isotretinoin Therapy for Cushing's Disease: Results of a Prospective Study. International Journal of Endocrinology...
| Schlagworte: | Oxoretinoic acid, 4-Oxoisotretinoin, Ro 22-6595 |
| Anwendung: | Active isotretinoin metabolite |
| CAS | 71748-58-8 |
| MW: | 314.42 D |
ab 57,00 €
AR7
Artikelnummer: TGM-T3955-100mg
Description: AR7 is a retinoic acid receptor alpha (RARalpha) antagonist. Target: Retinoid Receptor. Smiles: Cc1ccc(cc1)C1=Nc2ccc(Cl)cc2OC1. References: Anguiano J, et al. Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives. Nat Chem Biol. 2013 Jun,9(6):374-82.
| Anwendung: | Retinoic acid receptor alpha agonist |
| CAS | 80306-38-3 |
| MW: | 257.71 D |
ab 32,00 €
AM580
Artikelnummer: TGM-T5854-100mg
Description: AM580 (CD336) is a retinoic acid receptor agonist that is selective for RARalpha( IC50 : 8 nM ). Target: Retinoid Receptor, Autophagy. Smiles: CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)Nc1ccc(cc1)C(O)=O. References: Cheng Y H , Utsunomiya H , Pavone M E , et al. Retinoic acid inhibits endometrial cancer cell...
| Schlagworte: | CD336, NSC608001, Ro 40-6055 |
| Anwendung: | RAR alpha (retinoic acid receptor alpha) agonist |
| CAS | 102121-60-8 |
| MW: | 351.44 D |
ab 33,00 €
Tazarotenic acid
Artikelnummer: TGM-T7894-100mg
Description: Tazarotenic acid (AGN-190299) is a retinoid prodrug which is converted to its active form. Target: Others. Smiles: CC1(C)CCSc2ccc(cc12)C#Cc1ccc(cn1)C(O)=O. References: Poeirr Hsyu, Bowen B , Tang-Liu D . Pharmacokinetics of a novel retinoid AGN 190168 and its metabolite AGN 190299 after intravenous...
| Schlagworte: | AGN-190299 |
| Anwendung: | Retinoic acid receptor (RAR) agonist |
| CAS | 118292-41-4 |
| MW: | 323.41 D |
ab 59,00 €
AGN 193109 sodium
Artikelnummer: TGM-T85283-10mg
Description: AGN 193109 is a potent antagonist of retinoic acid receptors (RARs, Kd= 2, 2, and 3 nM for RARalpha, beta, and gamma, respectively), exhibiting selectivity for RARs over retinoid X receptors (RXRs, Kd= >10,000 nM for human RXRalpha, beta, and gamma receptors). This compound effectively reverses cellular...
| Schlagworte: | CD3106 |
| Anwendung: | Retinoic acid receptor antagonist |
| CAS | 2319838-82-7 |
| MW: | 414.5 D |
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TTNPB
Artikelnummer: TGM-T1288-100mg
Description: TTNPB (Ro 13-7410,AGN-191183), a potent RAR agonist, inhibits binding of [3H]tRA of human RARalpha (IC50: 5.1 nM), beta (IC50: 4.5 nM), and gamma (IC50: 9.3 nM), respectively. Target: Autophagy, Apoptosis, Retinoid Receptor. Smiles: CC(=Cc1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C. References:...
| Schlagworte: | Arotinoid acid, Ro 13-7410,AGN-191183, AGN191183, Ro 13-7410 |
| Anwendung: | Retinoic acid receptor agonist |
| CAS | 71441-28-6 |
| MW: | 348.48 D |
ab 33,00 €
Ch55
Artikelnummer: TGM-T14946-100mg
Description: Ch55 (3,5-Di-tert-butylchalcone) is an effective inducer of the differentiation of HL60 cells (EC50 = 200 nM) and shows high affinity with RAR-alpha and RAR-beta receptors. Ch55 can be used in studies about cancer. Target: Retinoid Receptor. Smiles:...
| Schlagworte: | 3,5-Di-tert-butylchalcone, CH 55, Ch-55 |
| Anwendung: | Retinoic acid receptor ligand |
| CAS | 110368-33-7 |
| MW: | 364.48 D |
ab 41,00 €
Anti-RARA Recombinant Monoclonal, clone 4A10
Artikelnummer: CSB-RA019338A0HU.100
Isotype: Rabbit IgG. Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity-chromatography. Target Name: RARA. Antigen Species: Human
| Schlagworte: | Anti-RARA, Anti-NR1B1, Anti-RAR-alpha, Anti-Retinoic acid receptor alpha, Anti-Nuclear receptor subfamily 1 group B member... |
| Anwendung: | ELISA, WB, IHC, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 201,00 €
Anti-RARA
Artikelnummer: CSB-PA237495.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: RARA. Antigen Species: Human
| Schlagworte: | Anti-RARA, Anti-NR1B1, Anti-RAR-alpha, Anti-Retinoic acid receptor alpha, Anti-Nuclear receptor subfamily 1 group B member... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 163,00 €