Zu "K08008" wurden 52 Artikel gefunden!
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VAS2870
Artikelnummer: TGM-T4359-100mg
Description: VAS2870 is an inhibitor of NADPH oxidase (NOX). Target: NADPH. Smiles: C(c1ccccc1)n1nnc2c(Sc3nc4ccccc4o3)ncnc12. References: ten Freyhaus H, et al. Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferation. Cardiovasc Res. 2006 Jul 15,71(2):331-41.
| Anwendung: | Cell-permeable specific NADPH oxidase inhibitor |
| CAS | 722456-31-7 |
| MW: | 360.39 D |
ab 52,00 €
NOX1 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-01744-100ug
Description: NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as...
| Schlagworte: | NADH/NADPH mitogenic oxidase subunit P65-MOX, NADPH oxidase 1, Mitogenic oxidase 1, NOH-1, NOX1 |
| MW: | 67.7 kD |
ab 2.633,00 €
Setanaxib
Artikelnummer: TGM-T6099-100mg
Description: Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor. Target: Ferroptosis, NADPH-oxidase, NADPH. Smiles: CN(C)c1cccc(c1)-c1n(C)c(=O)cc2[nH]n(-c3ccccc3Cl)c(=O)c12. References: Aoyama T, et al. Hepatology. 2012, 56(6), 2316-2327.
| Schlagworte: | GKT137831 |
| Anwendung: | NOX1 & NOX4 inhibitor |
| CAS | 1218942-37-0 |
| MW: | 394.85 D |
ab 34,00 €
GKT137831
Artikelnummer: Cay17764-1
NADPH oxidase 1 (NOX1) and NOX4 generate reactive oxygen species (ROS) that are critical in regulating a variety of cellular functions but also contribute to many diseases. GKT137831 is a dual inhibitor of both NOX1 and NOX4 with Ki values in the range of 100 to 150 nM in cell-free assays of ROS production. It shows...
| Schlagworte: | 2-(2-chlorophenyl)-4-[3-(dimethylamino)phenyl]-5-methyl-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione |
| Anwendung: | NOX1 & NOX4 inhibitor |
| CAS | 1218942-37-0 |
| MW: | 394.9 D |
ab 44,00 €
NADPH oxidase 1 (NOX1), human, recombinant
Artikelnummer: CSB-CF015959HU.100
Organism: Homo sapiens (Human). Source: in vitro E.coli expression system. Expression Region: 1-564aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MGNWVVNHWF SVLFLVVWLG LNVFLFVDAF LKYEKADKYY YTRKILGSTL ACARASALCL NFNSTLILLP VCRNLLSFLR GTCSFCSRTL RKQLDHNLTF HKLVAYMICL...
| Schlagworte: | MOX1, NOX1, MOX-1, NOX-1, NOH-1, EC=1.-.-.-, NADPH oxidase 1, Mitogenic oxidase 1, NADH/NADPH mitogenic oxidase subunit... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli in vitro |
| Ursprungsart: | human |
| MW: | 67.7 kD |
ab 1.458,00 €
Anti-NOX1
Artikelnummer: CSB-PA120772.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: NOX1. Antigen Species: Human
| Schlagworte: | Anti-NOX1, Anti-MOX1, Anti-NOH-1, Anti-MOX-1, Anti-NOX-1, EC=1.-.-.-, Anti-NADPH oxidase 1, Anti-Mitogenic oxidase 1,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-NOX1
Artikelnummer: CSB-PA220321.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: NOX1. Antigen Species: Human
| Schlagworte: | Anti-NOX1, Anti-MOX1, Anti-NOH-1, Anti-MOX-1, Anti-NOX-1, EC=1.-.-.-, Anti-NADPH oxidase 1, Anti-Mitogenic oxidase 1,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-NOX1
Artikelnummer: CSB-PA443876.100
Host Species: Rabbit. Isotype: IgG. Buffer: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific...
| Schlagworte: | Anti-NOX1, Anti-MOX1, Anti-NOH-1, Anti-MOX-1, Anti-NOX-1, EC=1.-.-.-, Anti-NADPH oxidase 1, Anti-Mitogenic oxidase 1,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-NOX1
Artikelnummer: CSB-PA924751.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-NOX1, Anti-MOX1, Anti-NOH-1, Anti-MOX-1, Anti-NOX-1, EC=1.-.-.-, Anti-NADPH oxidase 1, Anti-Mitogenic oxidase 1,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
283,00 €
2-Acetylphenothiazine
Artikelnummer: Cay19056-10
2-Acetylphenothiazine (2-APT) is a selective, cell-active inhibitor of NADPH oxidase 1 (NOX1) that blocks the generation of reactive oxygen species (ROS) in HT-29 cells with an IC50 value of 0.129 µM. It does not affect xanthine oxidase-dependent or mitochondrial ROS generation. 2-APT prevents ROS-dependent...
| Schlagworte: | 2-APT, ML-171, NSC 169669, NSC 57951, 1-(10H-phenothiazin-2-yl)-ethanone |
| Anwendung: | NOX1 inhibitor |
| CAS | 6631-94-3 |
| MW: | 241.3 D |
ab 44,00 €
ML-090
Artikelnummer: Cay15172-10
NADPH oxidase 1 (NOX1) generates reactive oxygen species (ROS) in colon epithelial cells that interacts with both pathogenic and normal bacteria. Excess ROS production, however, is associated with damage to the intestinal mucosa, inflammatory bowel disease, and prostate cancer. ML-090 is the first identified...
| Schlagworte: | CCG-44699, CID-616479, Fluoflavin, NSC 179821, 5,12-dihydro-quinoxalino[2,3-b]quinoxaline |
| Anwendung: | NADPH oxidase 1 (NOX-1) inhibitor |
| CAS | 531-46-4 |
| MW: | 234.3 D |
ab 44,00 €
VAS2870
Artikelnummer: Cay19205-1
VAS2870 is a selective inhibitor of the NADPH oxidases. Pre-incubation of rat vascular smooth muscle cells with VAS2870 abolishes platelet-derived growth factor-dependent chemotaxis without affecting cell cycle progression (IC50 = 10 µM). At low (2.8 mM), but not high (16.7 mM), concentrations of glucose, treatment...
| Schlagworte: | 7-(2-benzoxazolylthio)-3-(phenylmethyl)-3H-1,2,3-triazolo[4,5-d]pyrimidine |
| Anwendung: | Cell-permeable specific NADPH oxidase inhibitor |
| CAS | 722456-31-7 |
| MW: | 360.4 D |
ab 44,00 €