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ML-098
Artikelnummer: TGM-T4619-100mg
Description: ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 with an EC50 value of 77.6 nM. Target: Ras. Smiles: Cc1ccc(C)c(OCCn2cc(C(O)=O)c3ccccc23)c1. References: Surviladze, Z., Ursu, O., Miscisocia, F., et al. UNMCMD Probe Report: Three small molecule pan activator families of Ras-related...
| Schlagworte: | CID-7345532 |
| Anwendung: | Rab7 activator |
| CAS | 878978-76-8 |
| MW: | 309.36 D |
ab 34,00 €
CID-1067700
Artikelnummer: TGM-T7558-100mg
Description: CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases(Rab7 with a Ki of 13 nM). Target: Ras. Smiles: CC1(C)Cc2c(CO1)sc(NC(=S)NC(=O)c1ccccc1)c2C(O)=O. References: Agola J O , Hong L , Surviladze Z , et al. A Competitive Nucleotide Binding...
| Anwendung: | Rab7 inhibitor |
| CAS | 314042-01-8 |
| MW: | 390.48 D |
ab 31,00 €
RAB7A Protein, Rat, Recombinant (His)
Artikelnummer: TGM-TMPY-04152-100ug
Description: RAB7A is a ubiquitous small GTPase, which controls transport to late endocytic compartments. Silencing or overexpression of wild type RAB7A changed the soluble/insoluble rate of peripherin indicating that RAB7A is important for peripherin organization and function. Besides, disease-causing RAB7A mutant...
| Schlagworte: | Rab7, RAB7A, member RAS oncogene family |
| MW: | 25.7 kD |
497,00 €
Anti-Active Rab7, monoclonal
Artikelnummer: NB-26923
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Rab7 belongs to the Rab family of small GTPases. Rab7 is located in the late endosome, lysosome, cytoplasmic vesicle, phagosome and melanosome. It is involved in the late endocytic transport and contributes to...
| Schlagworte: | Anti-RAB7, Anti-RAB7A, Anti-Ras-related protein Rab-7a |
| Anwendung: | IP, IHC, IF |
| Wirt: | Mouse |
| Spezies-Reaktivität: | vertebrates |
731,00 €
Anti-Rab7A
Artikelnummer: NB-21069
Concentration: 0.2 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Rab7A belongs to the Rab family of small GTPases. Rab7A is located in the late endosome, lysosome, cytoplasmic vesicle, phagosome and melanosome. It is involved in the late endocytic transport and contributes to...
| Schlagworte: | Anti-RAB7, Anti-RAB7A, Anti-Ras-related protein Rab-7a |
| Anwendung: | ELISA, WB, IHC, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | vertebrates |
323,00 €
CID-1067700
Artikelnummer: Cay15194-5
The Ras family of GTPases, including the Arf, Rho, Ras, and Rab GTPase subfamilies, regulates various cellular processes ranging from membrane trafficking to the control of cell proliferation. They regulate cell physiology by switching between active and inactive conformational states by binding either GTP or GDP....
| Schlagworte: | ML-282, 2-[[(benzoylamino)thioxomethyl]amino]-4,7-dihydro-5,5-dimethyl-5H-thieno[2,3-c]pyran-3-carboxylic acid |
| Anwendung: | Rab7 inhibitor |
| CAS | 314042-01-8 |
| MW: | 390.5 D |
ab 52,00 €
ML-098
Artikelnummer: Cay15175-1
The Ras family of GTPases, including the Arf, Rho, Ras, and Rab GTPase subfamilies, regulates various cellular processes ranging from membrane trafficking to the control of cell proliferation. They regulate cell physiology by switching between active and inactive conformational states by binding either GTP or GDP....
| Schlagworte: | CID-7345532, 1-[2-(2,5-dimethylphenoxy)ethyl]-1H-indole-3-carboxylic acid |
| Anwendung: | Rab7 activator |
| CAS | 878978-76-8 |
| MW: | 309.4 D |
ab 61,00 €
Anti-RAB7, clone 10E4
Artikelnummer: ARG57498.50
Protein function: Key regulator in endo-lysosomal trafficking. Governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades. Plays a central role, not only in...
| Schlagworte: | Anti-RAB7, Anti-RAB7A, Anti-Ras-related protein Rab-7a |
| Anwendung: | FC, ICC, IF, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
518,00 €
Anti-Rab-7
Artikelnummer: 600-401-I05
Anti-Rab-7 Antibody was purified by peptide affinity chromatography. A BLAST analysis was used to suggest cross-reactivity with Rab-7 from rat and New World monkey based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-Rab-7 from other sources has not been determined. Protein function: Key...
| Schlagworte: | Anti-RAB7, Anti-RAB7A, Anti-Ras-related protein Rab-7a |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
805,00 €
Anti-RAB7A
Artikelnummer: NSJ-R32124
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Ras-related protein Rab-7a is a protein that in humans is encoded by the RAB7A gene. RAB7A functions as a key regulator in endo-lysosomal trafficking, governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal...
| Schlagworte: | Anti-RAB7, Anti-RAB7A, Anti-Ras-related protein Rab-7a, RAB7A Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
772,00 €
Anti-Rab7, monoclonal
Artikelnummer: NB-26055
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Rab7 belongs to the Rab family of small GTPases. Rab7 is located in the late endosome, lysosome, cytoplasmic vesicle, phagosome and melanosome. It is involved in the late endocytic transport and contributes to the...
| Schlagworte: | Anti-RAB7, Anti-RAB7A, Anti-Ras-related protein Rab-7a |
| Anwendung: | ELISA, WB, IHC, IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | vertebrates |
353,00 €
Rab7 Q67L mutant (Member RAS oncogene family, Rab7a,...
Artikelnummer: NB-10135
Members of the Rab family of Ras-related GTP-binding proteins are important regulators of vesicular transport and are located in specific intracellular compartments. Rab7 has been localized to late endosomes and shown to be important in the late endocytic pathway. In addition, it has been shown to have a fundamental...
| Schlagworte: | RAB7, RAB7A, Ras-related protein Rab-7a |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 23 kD |
366,00 €