Zu "K07827" wurden 116 Artikel gefunden!
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NEU
K-Ras Isoform B (G12C, C51S, C80L, C118S mutant, human,...
Artikelnummer: Cay40366-100
K-Ras is a small GTPase and member of the RAS family of GTPases with roles in apoptosis, as well as cell proliferation, survival, and migration. K-Ras is composed of a guanine nucleotide-binding domain containing an active site, an effector-binding domain, and an isoform-specific C-terminal hypervariable region,...
| Schlagworte: | KRAS, KRAS2, Ki-Ras, K-Ras 2, c-K-ras, c-Ki-ras, GTPase KRas, GTPase KRas, N-terminally processed |
| Anwendung: | Active enzyme |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
448,00 €
NEU
GTPase KRas (KRAS), partial, human, recombinant
Artikelnummer: CSB-EP012493HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 2-168aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: TEYKLVVVGA GGVGKSALTI QLIQNHFVDE YDPTIEDSYR KQVVIDGETC LLDILDTAGQ EEYSAMRDQY MRTGEGFLCV FAINNTKSFE DIHHYREQIK RVKDSEDVPM VLVGNKCDLP SRTVDTKQAQ DLARSYGIPF...
| Schlagworte: | KRAS, KRAS2, Recombinant Human GTPase KRas (KRAS), partial |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 23.1 kD |
ab 213,00 €
ML-162-yne
Artikelnummer: Cay40783-10
ML-162-yne is an alkyne derivative of ML-162 (Cay-20455). It has been used in the synthesis of the proteolysis-targeting chimera (PROTAC) and GPX4 degrader dGPX4.Formal Name: alpha-[(2-chloroacetyl)[3-chloro-4-(2-propyn-1-yloxy)phenyl]amino]-N -(2-phenylethyl)-2-thiopheneacetamide. CAS Number: 2883115-46-4....
| Schlagworte: | alpha-[(2-chloroacetyl)[3-chloro-4-(2-propyn-1-yloxy)phenyl]amino]-N -(2-phenylethyl)-2-thiopheneacetamide |
| Anwendung: | ML-162 alkyne derivative, PROTAC synthesis |
| CAS | 2883115-46-4 |
| MW: | 501.4 D |
ab 47,00 €
K-Ras(G12D) Isoform A (human, recombinant)
Artikelnummer: Cay40372-100
K-Ras is a small GTPase and member of the RAS family of GTPases with roles in apoptosis, as well as cell proliferation, survival, and migration. K-Ras is composed of a guanine nucleotide-binding domain containing an active site, an effector binding domain, and an isoform-specific C-terminal hypervariable region...
| Schlagworte: | KRAS, KRAS2, Ki-Ras, K-Ras 2, c-K-ras, c-Ki-ras, GTPase KRas, GTPase KRas, N-terminally processed |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 23 kD |
448,00 €
K-Ras(G12V) Isoform B (human, recombinant)
Artikelnummer: Cay40373-100
K-Ras is a small GTPase and member of the RAS family of GTPases with roles in apoptosis, as well as cell proliferation, survival, and migration. K-Ras is composed of a guanine nucleotide-binding domain containing an active site, an effector binding domain, and an isoform-specific C-terminal hypervariable region...
| Schlagworte: | KRAS, KRAS2, Ki-Ras, K-Ras 2, c-K-ras, c-Ki-ras, GTPase KRas, GTPase KRas, N-terminally processed |
| Anwendung: | Active |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
| MW: | 22 kD |
448,00 €
K-Ras(G12C) Isoform A (human, recombinant)
Artikelnummer: Cay40371-100
K-Ras is a small GTPase and member of the RAS family of GTPases with roles in apoptosis, as well as cell proliferation, survival, and migration. K-Ras is composed of a guanine nucleotide binding domain containing an active site, an effector binding domain, and an isoform-specific C-terminal hypervariable region,...
| Schlagworte: | KRAS, KRAS2, Ki-Ras, K-Ras 2, c-K-ras, c-Ki-ras, GTPase KRas, GTPase KRas, N-terminally processed |
| Ursprungsart: | human |
448,00 €
Erastin
Artikelnummer: Cay17754-10
Erastin, named for eradicator of RAS and small T (ST) antigen-expressing cells, is a ferroptosis inducer. It induces ferroptotic cell death in vitro, an effect that can be blocked by the ferroptosis inhibitors ciclopirox olamine, Trolox (Cay-10011659), ferrostatin-1 (Cay-17729), U-0126 (Cay-70970), cycloheximide...
| Schlagworte: | 2-[1-[4-[2-(4-chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone |
| Anwendung: | Antitumor agent |
| CAS | 571203-78-6 |
| MW: | 547.1 D |
ab 60,00 €
Rat KRAS (V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene...
Artikelnummer: ELK-ELK0390.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat KRAS. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat KRAS. Next,...
| Schlagworte: | Kras, Kras2 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 352,00 €
Anti-Active Ras, monoclonal
Artikelnummer: NB-26909
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Small GTPases are a super-family of cellular signaling regulators. Ras belongs to the Ras sub-family of GTPases that regulate cell proliferation, cell motility, and gene transcription. GTP binding increases the...
| Schlagworte: | Anti-KRAS, Anti-KRAS2 |
| Anwendung: | IP, IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | vertebrates |
717,00 €
Anti-Ras (G12D), monoclonal
Artikelnummer: NB-26036
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Ras (G12D) is one type of Ras missense mutations at the codon 12. Ras protein is a membrane-associated GTPase that regulates cell proliferation, differentiation, and survival. Ras G12D mutation results in...
| Schlagworte: | Anti-KRAS, Anti-KRAS2 |
| Anwendung: | ELISA, WB, IHC, IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | vertebrates |
717,00 €
Anti-Ras (G13D), monoclonal
Artikelnummer: NB-26038
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Ras (G13D) is one type of Ras missense mutations at the codon 13. Ras protein is a membrane-associated GTPase that regulates cell proliferation, differentiation, and survival. Ras G13D mutation results in...
| Schlagworte: | Anti-KRAS, Anti-KRAS2 |
| Anwendung: | ELISA, WB, IHC, IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | vertebrates |
717,00 €
ML-162
Artikelnummer: Cay20455-1
ML-162 is an inhibitor of glutathione peroxidase 4 (GPX4). It decreases GPX4 levels in MDA-MB-231 breast cancer cells, as well as the viability of BT-549 breast cancer cells, an effect that is enhanced by alpha-eleostearic acid (9(Z),11(E),13(E)-octadecatrienoic acid, Cay-10008349). ML-162 is also selectively lethal...
| Schlagworte: | alpha-[(2-chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thiopheneacetamide |
| Anwendung: | GPX4 inhibitor, antitumor agent |
| CAS | 1035072-16-2 |
| MW: | 477.4 D |
ab 62,00 €