Zu "K07759" wurden 37 Artikel gefunden!
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Anti-PARG
Artikelnummer: ATA-HPA041247.100
Polyclonal Antibody against Human PARG, Gene description: poly(ADP-ribose) glycohydrolase, Validated applications: ICC, Uniprot ID: Q86W56, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: Poly(ADP-ribose) glycohydrolase that degrades poly(ADP- ribose) by...
| Schlagworte: | Anti-Poly(ADP-ribose) glycohydrolase |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
477,00 €
PDD00017273
Artikelnummer: TGM-T5700-100mg
Description: PDD00017273 is a radiosensitizing PARG) inhibitor with antitumor or activity for the study of epithelial ovaries. Target: Others. Smiles: Cc1cc(Cn2c3ccc(cc3c(=O)n(Cc3cnc(C)s3)c2=O)S(=O)(=O)NC2(C)CC2)n(C)n1. References: Gravells P, et al. Specific killing of DNA damage-response deficient cells with...
| Anwendung: | PARG inhibitor |
| CAS | 1945950-21-9 |
| MW: | 514.62 D |
ab 75,00 €
PARG Inhibitor PDD00017273
Artikelnummer: AG-CR1-3646-M001
White to off-white solid. Soluble in DMSO, methanol or acetonitrile. Human poly(ADP-ribose) glycohydrolase (PARG) inhibitor for in vitro studies, Inhibits human recombinant PARG enzymes (IC50=26nM) and PARG in cell assays (IC50=37nM). Inactive against related glycohydrolases ARH3 and PARP1s (IC50>,30µ,M)....
| Schlagworte: | PARG Inhibitor Compound 4,... |
| Anwendung: | PARG inhibitor |
| CAS | 1945950-21-9 |
| MW: | 514,6 D |
ab 72,00 €
Anti-PARG
Artikelnummer: A305-405A
Protein function: Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase (PubMed:23102699). PARG acts both as an endo- and exoglycosidase, releasing PAR of different length as well as ADP- ribose monomers (PubMed:23102699). Required for...
| Schlagworte: | Anti-PARG, EC=3.2.1.143, Anti-Poly(ADP-ribose) glycohydrolase |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
Anti-PARG
Artikelnummer: A305-410A
Protein function: Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase (PubMed:23102699). PARG acts both as an endo- and exoglycosidase, releasing PAR of different length as well as ADP- ribose monomers (PubMed:23102699). Required for...
| Schlagworte: | Anti-PARG, EC=3.2.1.143, Anti-Poly(ADP-ribose) glycohydrolase |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
Anti-PARG
Artikelnummer: ARG40973.100
Protein function: Poly(ADP-ribose) glycohydrolase that degrades poly(ADP- ribose) by hydrolyzing the ribose-ribose bonds present in poly(ADP-ribose) (PubMed:21892188, PubMed:23102699, PubMed:23474714). PARG acts both as an endo- and exoglycosidase, releasing poly(ADP-ribose) of different length as well as ADP-...
| Schlagworte: | Anti-Poly(ADP-ribose) glycohydrolase |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
616,00 €
Anti-PARG
Artikelnummer: ARG41050.100
Protein function: Poly(ADP-ribose) glycohydrolase that degrades poly(ADP- ribose) by hydrolyzing the ribose-ribose bonds present in poly(ADP-ribose) (PubMed:21892188, PubMed:23102699, PubMed:23474714). PARG acts both as an endo- and exoglycosidase, releasing poly(ADP-ribose) of different length as well as ADP-...
| Schlagworte: | Anti-Poly(ADP-ribose) glycohydrolase |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
658,00 €
PDD00017273
Artikelnummer: Cay19511-1
PDD00017273 is a poly(ADP-ribose) glycohydrolase (PARG) inhibitor (IC50 = 26 nM in an enzyme assay). It maintains persistence of nuclear PAR chains in HeLa cells induced by the DNA damaging agent methylmethanesulfonate (MMS, IC50 = 37 nM). PDD00017273, in combination with MMS, increases nuclear phosphorylated H2AX...
| Schlagworte: | 1-[(1,3-dimethyl-1H-pyrazol-5-yl)methyl]-1,2,3,4-tetrahydro-N-(1-methylcyclopropyl)-3-[(2-methyl-5-thiazolyl)methyl]-2,4-d... |
| Anwendung: | PARG inhibitor |
| CAS | 1945950-21-9 |
| MW: | 514.6 D |
ab 61,00 €
Anti-PARG
Artikelnummer: ATA-HPA021819.100
Protein function: Poly(ADP-ribose) glycohydrolase that degrades poly(ADP- ribose) by hydrolyzing the ribose-ribose bonds present in poly(ADP- ribose) (PubMed:21892188, PubMed:23102699, PubMed:23474714). PARG acts both as an endo- and exoglycosidase, releasing poly(ADP-ribose) of different length as well as...
| Schlagworte: | Anti-Poly(ADP-ribose) glycohydrolase |
| Anwendung: | ICC, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €
Anti-PARG
Artikelnummer: ATA-HPA053007.100
Protein function: Poly(ADP-ribose) glycohydrolase that degrades poly(ADP- ribose) by hydrolyzing the ribose-ribose bonds present in poly(ADP- ribose) (PubMed:21892188, PubMed:23102699, PubMed:23474714). PARG acts both as an endo- and exoglycosidase, releasing poly(ADP-ribose) of different length as well as...
| Schlagworte: | Anti-Poly(ADP-ribose) glycohydrolase |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €
PARG, His-Tag Recombinant
Artikelnummer: BPS-101726
Recombinant human PARG (Poly(ADP-ribose) glycohydrolase), full length encompassing amino acids 2-976 (end). The construct contains an N-terminal His-Tag (6xHis). The recombinant protein was affinity purified.
| Schlagworte: | Poly(ADP-ribose) glycohydrolase, PARG (His-2-976(end)) |
| Anwendung: | Enzyme kinetics, Inhibitor screening, Selectivity profiling |
| Ursprungsart: | human |
819,00 €
PARG Fluorogenic Assay Kit
Artikelnummer: BPS-78858-1
The PARG Fluorogenic Assay Kit is a high-throughput, homogeneous 384-well assay designed to measure the hydrolase activity of Poly (ADP-ribose) glycohydrolase (PARG) for screening and profiling applications, using a simple and straightforward fluorogenic assay. The PARG Fluorogenic Assay Kit contains enough purified...
| Schlagworte: | Poly(ADP-ribose) glycohydrolase, |
| Anwendung: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Spezies-Reaktivität: | human |
ab 1.270,00 €