Zu "K07434" wurden 64 Artikel gefunden!
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17beta-hydroxy Exemestane
Artikelnummer: TGM-T35676-1mg
Description: 17beta-hydroxy Exemestane is the primary active metabolite of exemestane . It is formed by metabolism of exemestane by the cytochrome P450 (CYP) isoforms CYP1A and CYP4A11. 17beta-hydroxy Exemestane is an aromatase inhibitor (IC50 = 69 nM using human placental microsomes) and an androgen receptor (AR)...
| Anwendung: | Primary active exemestane metabolite, aromatase inhibitor |
| CAS | 122370-91-6 |
| MW: | 298.42 D |
657,00 €
Vorozole
Artikelnummer: TGM-T26322-1mg
Description: Vorozole (R83842) is an orally active, potent, and selective nonsteroidal aromatase inhibitor.Vorozole exhibits antitumor activity in vivo and may be used in the study of breast cancer. Target: Aromatase, P450. Smiles: [C@@H](C=1C=C2C(=CC1)N=NN2C)(C3=CC=C(Cl)C=C3)N4C=NC=N4. References: Wouters W, et...
| Schlagworte: | R 83839, R-83839, R83839, R83842, (+)-Vorozole |
| Anwendung: | Targets aromatase [EC:1.14.14.14] (CYP19A) |
| CAS | 129731-10-8 |
| MW: | 324.77 D |
ab 190,00 €
Aromatase inhibitor 23
Artikelnummer: TGM-T60006-100mg
Description: Aromatase inhibitor 23 is an inhibitor that target protein-protein interactions in RAD51 family of recombinases. Target: Others. Smiles: C(CNS(=O)(=O)C1=CC=CC=C1)C=2C=3C(NC2)=CC=CC3. References: Scott DE, et al. Small-molecule inhibitors that target protein-protein interactions in the RAD51 family of...
| Anwendung: | Aromatase inhibitor |
| CAS | 32585-54-9 |
| MW: | 300.38 D |
ab 117,00 €
Plomestane
Artikelnummer: TGM-T68720-100mg
Description: Plomestane is a selective inhibitor of aromatization in human breast tissue and may provide a mechanism for controlling estrogen responsive processes. Target: Others. Smiles: C(C#C)[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)C(=O)CC4)[H])(CCC1=CC(=O)CC2)[H])[H]
| Anwendung: | Targets aromatase [EC:1.14.14.14] (CYP19A) |
| CAS | 77016-85-4 |
| MW: | 310.43 D |
ab 1.820,00 €
Fadrozole
Artikelnummer: TGM-T7197-100mg
Description: Fadrozole is a nonsteroidal aromatase inhibitor with potential antineoplastic activity(IC50 : 6.4 nM). Target: Aromatase. Smiles: N#Cc1ccc(cc1)C1CCCc2cncn12. References: Schroeder A L , Ankley G T , Habib T , et al. Rapid Effects of the Aromatase Inhibitor Fadrozole on Steroid Production and Gene...
| Anwendung: | Targets aromatase [EC:1.14.14.14] (CYP19A) |
| CAS | 102676-47-1 |
| MW: | 223.27 D |
ab 45,00 €
Fadrozole hydrochloride
Artikelnummer: TGM-T7556-100mg
Description: Fadrozole hydrochloride (CGS 16949A) is a model aromatase inhibitor that effectively suppresses estrogen production in fish ovaries. Target: Aromatase. Smiles: Cl.N#Cc1ccc(cc1)C1CCCc2cncn12. References: Tekmal R R , Durgam V R . A novel in vitro and in vivo breast cancer model for testing inhibitors of...
| Schlagworte: | CGS 16949A |
| Anwendung: | Targets aromatase [EC:1.14.14.14] (CYP19A) |
| CAS | 102676-31-3 |
| MW: | 259.73 D |
ab 42,00 €
Aromatase/CYP19A1 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-00956-100ug
Description: Aromatase/CYP19A1 Protein, Human, Recombinant (His) is expressed in E. coli.
| Schlagworte: | CYP19, CYAR, Cytochrome P-450AROM, CYPXIX, ARO1, CYP19A1, Estrogen synthase, Aromatase, Cytochrome P450 19A1 |
| MW: | 62.0 kD |
ab 281,00 €
Liarozole fumarate
Artikelnummer: TGM-T25716-25mg
Description: Liarozole fumarate is used as a retinoic acid metabolism blocking agent (RAMBA) and an aromatase inhibitor. Target: Others. Smiles: OC(/C=C/C(O)=O)=O.ClC1=CC=CC(C(N2C=CN=C2)C3=CC=C(N=CN4)C4=C3)=C1.OC(/C=C/C(O)=O)=O.ClC5=CC=CC(C(N6C=CN=C6)C7=CC=C(N=CN8)C8=C7)=C5.OC(/C=C/C(O)=O)=O. References: Goss PE,...
| Schlagworte: | R 85246, Liazal, R-85246, R85246 |
| Anwendung: | Targets aromatase [EC:1.14.14.14] (CYP19A) |
| CAS | 145858-52-2 |
| MW: | 482.88 D |
1.520,00 €
Liarozole HCl
Artikelnummer: TGM-T25716L-100mg
Description: Liarozole HCl is a benzimidazole derivative with antineoplastic activity. As a retinoic acid metabolism blocking agent, liarozole inhibits CYP450-dependent all-trans-retinoic acid (ATRA)-4-hydroxylase, leading to an increase in endogenous ATRA production, inhibition of cell proliferation, and induction...
| Schlagworte: | R 75251, R-75251, R75251, Liarozole hydrochloride |
| Anwendung: | Targets aromatase [EC:1.14.14.14] (CYP19A) |
| CAS | 145858-50-0 |
| MW: | 345.23 D |
ab 1.671,00 €
Letrozole
Artikelnummer: TGM-T1590-25mg
Description: Letrozole (CGS 20267) is an Aromatase Inhibitor. The mechanism of action of letrozole is as an Aromatase Inhibitor. Target: Autophagy, Aromatase. Smiles: N#CC1=CC=C(C=C1)C(N1C=NC=N1)C1=CC=C(C=C1)C#N. References: Haynes BP, et al. J Steroid Biochem Mol Biol, 2003, 87(1), 35-45.
| Schlagworte: | CGS 20267 |
| Anwendung: | Targets aromatase [EC:1.14.14.14] (CYP19A) |
| CAS | 112809-51-5 |
| MW: | 285.3 D |
ab 31,00 €
Aromatase (CYP19A1), human, recombinant
Artikelnummer: CSB-EP006394HUa0.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-503aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MVLEMLNPIH YNITSIVPEA MPAATMPVLL LTGLFLLVWN YEGTSSIPGP GYCMGIGPLI SHGRFLWMGI GSACNYYNRV YGEFMRVWIS GEETLIISKS SSMFHIMKHN HYSSRFGSKL GLQCIGMHEK...
| Schlagworte: | ARO1, CYPXIX, Aromatase, Estrogen synthase, Cytochrome P-450AROM, Cytochrome P450 19A1, Recombinant Human Aromatase (CYP19A1) |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 62.0 kD |
ab 292,00 €
Anti-CYP19A1
Artikelnummer: CSB-PA001927.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-ARO1, Anti-CYPXIX, Anti-Aromatase, Anti-Estrogen synthase, Anti-Cytochrome P450 19A1, Anti-Cytochrome P-450AROM, ARO... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
126,00 €