Zu "K07424" wurden 22 Artikel gefunden!
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alpha-Hydroxymidazolam
Artikelnummer: Cay10385-5
alpha-Hydroxymidazolam is the major metabolite of the anesthetic, midazolam. It is produced rapidly by the actions of hepatic cytochrome P450 3A and has been shown to be equipotent to midazolam.Formal Name: 8-chloro-6-(2-fluorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepine-1-methanol. CAS Number: 59468-90-5. Synonyms:...
| Schlagworte: | Ro 21-6347, alpha-Hydroxymidazolam, 8-chloro-6-(2-fluorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepine-1-methanol |
| CAS | 59468-90-5 |
| MW: | 341.8 D |
ab 178,00 €
Desmethyl Ranolazine
Artikelnummer: TGM-T36723-10mg
Description: Desmethyl ranolazine is a metabolite of the antianginal agent ranolazine .1It is formed from ranolazine by the cytochrome P450 (CYP) isoform CYP3A. Target: Others. Smiles: Cc1cccc(C)c1NC(=O)CN1CCN(CC(O)COc2ccccc2O)CC1. References: Wang, Y., Chen, X., Sun, Z., et al.Development and validation of a...
| Anwendung: | Ranolazine metabolite |
| CAS | 172430-45-4 |
| MW: | 413.518 D |
ab 251,00 €
11alpha-hydroxy Testosterone
Artikelnummer: TGM-T84532-10mg
Description: 11alpha-Hydroxy Testosterone, a testosterone metabolite, is synthesized by the cytochrome P450 (CYP) isoform CYP3A.1, and can alternatively be produced from testosterone by a CYP107A1 mutant or from 11alpha-hydroxy progesterone by the fungus B. bassiana.2,3 The biological activity of 11alpha-Hydroxy...
| Anwendung: | Bioactive lipid assays |
| CAS | 3066-12-4 |
| MW: | 304.4 D |
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Cytochrome P450 3A25 (Cyp3a25), mouse, recombinant
Artikelnummer: CSB-EP515508MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 1-503aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MELIPNLSIE TWVLLVTSLV LFYIYGTYSH GLFKKLGIPG PKPLPLLGTI FNYYDGMWKF DEDCYKKYGK IWGFYEGPQP ILAIMDPEII KIVLVKECYS VFTNRRFFGP...
| Schlagworte: | Cyp3a25, CYPIIIA25, EC=1.14.14.1, Cytochrome P450 3A25, Recombinant Mouse Cytochrome P450 3A25 (Cyp3a25) |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 65.6 kD |
ab 364,00 €
Cytochrome P450 3A16 (Cyp3a16), mouse, recombinant
Artikelnummer: CSB-EP714495MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 1-504aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MNLFSALSLD TLVLLAIILV LLYRYGTCTH GLFKKQGIPG PKPLPFLGTV LNYYKGLWKF DMECYEKYGK TWGLFDGQIP LFVITDPETI KNVLVKECFS VFTNRQDFFP VGIMSKSISL AKDEEWKRYR...
| Schlagworte: | Cyp3a16, Cyp3a-16, CYPIIIA16, EC=1.14.14.1, Cytochrome P450 3A16, Recombinant Mouse Cytochrome P450 3A16 (Cyp3a16) |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 63.8 kD |
ab 364,00 €
Cytochrome P450 3A13 (Cyp3a13), mouse, recombinant
Artikelnummer: CSB-EP731056MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 1-503aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: MDLIPNFSME TWMLLATSLV LLYLYGTHSH GIFKKLGIPG PKPLPFLGTI LAYQKGFWEC DIQCHKKYGK MWGLYDGRQP VLAITDPDII KTVLVKECYS TFTNRRRFGP VGILKKAISI SENEEWKRIR...
| Schlagworte: | Cyp3a13, Cyp3a-13, CYPIIIA13, EC=1.14.14.1, Cytochrome P450 3A13, Recombinant Mouse Cytochrome P450 3A13 (Cyp3a13) |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 73.5 kD |
ab 292,00 €
Cytochrome P450 3A11 (Cyp3a11), mouse, recombinant
Artikelnummer: CSB-EP737360MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 1-504aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MDLVSALSLE TWVLLAISLV LLYRYGTRKH ELFKKQGIPG PKPLPFLGTV LNYYKGLWKF DMECYKKYGK TWGLFDGQTP LLAVTDPETI KNVLVKECFS VFTNRRDFGP...
| Schlagworte: | Cyp3a11, Cyp3a-11, CYPIIIA11, EC=1.14.14.1, Cytochrome P-450UT, Cytochrome P450 3A11, Cytochrome P-450IIIAM1, Recombinant... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 65.3 kD |
ab 364,00 €
Crizotinib
Artikelnummer: LKT-C6935.5
A potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK).
| CAS | 877399-52-5 |
| MW: | 450.34 D |
ab 141,00 €
11alpha-hydroxy Testosterone
Artikelnummer: Cay10008647-5
11alpha-hydroxy Testosterone is a metabolite of testosterone, produced by the cytochrome P450 (CYP) isoform CYP3A. It can also be generated from testosterone by a mutant of CYP107A1 and from 11alpha-hydroxy progesterone by the fungus B. bassiana. The biological activity of this metabolite has not been...
| Schlagworte: | 11alpha,17beta-dihydroxy-androst-4-en-3-one |
| Anwendung: | Bioactive lipid assays |
| CAS | 3066-12-4 |
| MW: | 304.4 D |
ab 66,00 €
Desmethyl Ranolazine
Artikelnummer: Cay35002-1
Desmethyl ranolazine is a metabolite of the antianginal agent ranolazine (Cay-15604). It is formed from ranolazine by the cytochrome P450 (CYP) isoform CYP3A.Formal Name: N-(2,6-dimethylphenyl)-4-[2-hydroxy-3-(2-hydroxyphenoxy)propyl]-1-piperazineacetamide. CAS Number: 172430-45-4. Synonyms: CVT-2514, RS 88390....
| Schlagworte: | CVT-2514, RS 88390, N-(2,6-dimethylphenyl)-4-[2-hydroxy-3-(2-hydroxyphenoxy)propyl]-1-piperazineacetamide |
| Anwendung: | Ranolazine metabolite |
| CAS | 172430-45-4 |
| MW: | 413.5 D |
ab 138,00 €
CVT-2738
Artikelnummer: Cay35003-1
CVT-2738 is an active metabolite of the antianginal agent ranolazine (Cay-15604). It is formed from ranolazine by the cytochrome P450 (CYP) isoform CYP3A. CVT-2738 (100 mg/kg) inhibits increases in T-wave height and the RR interval in a mouse model of myocardial ischemia induced by isoprenaline (isoproterenol,...
| Schlagworte: | N-(2,6-dimethylphenyl)-1-piperazineacetamide |
| Anwendung: | Ranolazine active metabolite |
| CAS | 5294-61-1 |
| MW: | 247.3 D |
ab 44,00 €
Rabeprazole sulfone
Artikelnummer: Cay35076-1
Rabeprazole sulfone is a metabolite of the proton pump inhibitor rabeprazole (Cay-14939). It is formed from rabeprazole by the cytochrome P450 (CYP) isoform CYP3A. Rabeprazole sulfone has also been found as an impurity in bulk preparations of rabeprazole.Formal Name:...
| Schlagworte: | 2-[[[4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole |
| Anwendung: | Rabeprazole metabolite |
| CAS | 117976-47-3 |
| MW: | 375.4 D |
ab 92,00 €