Zu "K07410" wurden 47 Artikel gefunden!
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TMS
Artikelnummer: TGM-T3585-100mg
Description: TMS (2,3',4,5'-Tetramethoxystilbene) is a very selective and potent competitive inhibitor of P450 1B1 (CYP1A1). Target: P450. Smiles: COc1ccc(\C=C\c2cc(OC)cc(OC)c2)c(OC)c1. References: Einem Lindeman T,et al. The resveratrol analogue, 2,3',4,5'-tetramethoxystilbene, does not inhibit CYP gene expression,...
| Schlagworte: | (E)-2,3',4,5'-tetramethoxystilbene, 2,3',4,5'-Tetramethoxystilbene |
| Anwendung: | CYP1B1 inhibitor |
| CAS | 24144-92-1 |
| MW: | 300.35 D |
ab 47,00 €
DMU-2139
Artikelnummer: TGM-T8728-100mg
Description: DMU2139 is a specific CYP1B1 inhibitor (CYP1B1 and CYP1A1 with IC50 of 9 nM and 795 nM, respectively). Target: P450. Smiles: C(C=CC=1C=CC=NC1)(=O)C2=CC3=C(C=C(OC)C=C3)C=C2. References: Horley N J , Beresford K J M , Chawla T , et al. Discovery and characterization of novel CYP1B1 inhibitors based on...
| Anwendung: | CYP1B1 inhibitor |
| CAS | 104890-70-2 |
| MW: | 289.33 D |
ab 44,00 €
3-(2-Naphthalenyl)-1-(3-pyridinyl)-2-propen-1-one
Artikelnummer: TGM-T8729-100mg
Description: DMU2105 is a specific CYP1B1 inhibitor(CYP1B1 and CYP1A1 with IC50 of 10 nM and 742 nM, respectively). Target: P450. Smiles: C(=CC(=O)C=1C=CC=NC1)C2=CC3=C(C=C2)C=CC=C3. References: Horley N J , Beresford K J M , Chawla T , et al. Discovery and characterization of novel CYP1B1 inhibitors based on...
| Anwendung: | CYP1B1 inhibitor |
| CAS | 1031063-36-1 |
| MW: | 259.3 D |
ab 45,00 €
Cytochrome P450 1B1 (Cyp1b1), rat, recombinant
Artikelnummer: CSB-YP731067RA.1
Organism: Rattus norvegicus (Rat). Source: Yeast. Expression Region: 1-543aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MATSLSADSP QQLSSLSTQQ TILLLLVSVL AIVHLGQWLL RQWRRKPWSS PPGPFPWPLI GNAASVGRAS HLYFARLARR YGDVFQIRLG SCPVVVLNGE SAIHQALVQQ GGVFADRPPF ASFRVVSGGR...
| Schlagworte: | CYPIB1, Cytochrome P450RAP, Cytochrome P450 1B1, Hydroperoxy icosatetraenoate dehydratase, Recombinant Rat Cytochrome P450... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | rat |
| MW: | 61.9 kD |
ab 336,00 €
Cytochrome P450 1B1 (Cyp1b1), rat, recombinant
Artikelnummer: CSB-EP731067RA.1
Organism: Rattus norvegicus (Rat). Source: E.coli. Expression Region: 1-543aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MATSLSADSP QQLSSLSTQQ TILLLLVSVL AIVHLGQWLL RQWRRKPWSS PPGPFPWPLI GNAASVGRAS HLYFARLARR YGDVFQIRLG SCPVVVLNGE SAIHQALVQQ GGVFADRPPF ASFRVVSGGR...
| Schlagworte: | CYPIB1, Cytochrome P450RAP, Cytochrome P450 1B1, Hydroperoxy icosatetraenoate dehydratase, Recombinant Rat Cytochrome P450... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | rat |
| MW: | 64.6 kD |
ab 283,00 €
Anti-CYP1B1
Artikelnummer: CSB-PA001931.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-CYPIB1, Anti-Cytochrome P450 1B1, Anti-Hydroperoxy icosatetraenoate dehydratase, Aryl hydrocarbon hydroxylase... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
106,00 €
Anti-CYP1B1
Artikelnummer: CSB-PA078505.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CYP1B1. Antigen Species: Human
| Schlagworte: | Anti-CYPIB1, Anti-Cytochrome P450 1B1, Anti-Hydroperoxy icosatetraenoate dehydratase, Aryl hydrocarbon hydroxylase... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
Anti-CYP1B1
Artikelnummer: CSB-PA273340.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-CYPIB1, Anti-Cytochrome P450 1B1, Anti-Hydroperoxy icosatetraenoate dehydratase, Aryl hydrocarbon hydroxylase... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
275,00 €
Anti-CYP1B1
Artikelnummer: CSB-PA283874.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CYP1B1. Antigen Species: Human
| Schlagworte: | Anti-CYPIB1, Anti-Cytochrome P450 1B1, Anti-Hydroperoxy icosatetraenoate dehydratase, Aryl hydrocarbon hydroxylase... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
Alizarin
Artikelnummer: Cay11676-50
Alizarin is a small molecule inhibitor of cytochrome P450 isoforms CYP1A1, CYP1A2, and CYP1B1 (IC50s = 6.2, 10, and 2.7 µM, respectively). Alizarin acts as an antioxidant against iodophenol-derived phenoxyl radicals, superoxide anion radicals, and lipid peroxidation in rat liver microsomes. It also reduces hepatic...
| Schlagworte: | CI-58000, NSC 7212, 1,2-dihydroxy-9,10-anthracenedione |
| Anwendung: | CYP1A1 / CYP1A2 / CYP1B1 inhibitor |
| CAS | 72-48-0 |
| MW: | 240.2 D |
ab 43,00 €
DMU2139
Artikelnummer: Cay37301-5
DMU2139 is an inhibitor of the cytochrome P450 (CYP) isoform CYP1B1 (IC50 = 0.009 µM). It is selective for CYP1B1 over CYP1A1, CYP1A2, CYP3A4, and CYP2D6 (IC50s = 0.795, 1.2, 10.6, and 5 µM, respectively). DMU2139 enhances cisplatin-induced cell death in HEK293 cells overexpressing CYP1B1.Formal Name:...
| Schlagworte: | 1-(6-methoxy-2-naphthalenyl)-3-(3-pyridinyl)-2-propen-1-one |
| Anwendung: | CYP1B1 inhibitor |
| CAS | 104890-70-2 |
| MW: | 289.3 D |
ab 109,00 €
4-Hydroxyestradiol
Artikelnummer: Cay31508-10
4-Hydroxyestradiol is a catechol estrogen and minor metabolite of estrogen. 4-Hydroxyestradiol is formed from estrogen by the cytochrome P450 (CYP) isoform CYP1B1. Production of 4-hydroxyestradiol is increased in microsomes prepared from human mammary adenocarcinoma and fibroadenoma microsomes compared with...
| Schlagworte: | 4-Hydroxy-17beta-estradiol, (17beta)-estra-1,3,5(10)-triene-3,4,17-triol |
| Anwendung: | Catechol estrogen, Minor metabolite of estrogen |
| CAS | 5976-61-4 |
| MW: | 288.4 D |
ab 77,00 €