Zu "K07409" wurden 60 Artikel gefunden!
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Luotonin A
Artikelnummer: Cay14253-5
Luotonin A is an alkaloid originally isolated from a plant used in traditional Chinese medicine. It inhibits the growth of mouse leukemia P388 cells (IC50 = 1.8 µg/ml). Luotonin A is structurally similar to the alkaloid camptothecin (Cay-11694) and, like camptothecin, it binds to and stabilizes the topoisomerase...
| Schlagworte: | quino[2',3':3,4]pyrrolo[2,1-b]quinazolin-11(13H)-one |
| Anwendung: | Apoptosis inducer, CYP1A1 / CYP1A2 inhibitor |
| CAS | 205989-12-4 |
| MW: | 285.3 D |
ab 39,00 €
7-BFC
Artikelnummer: TGM-T117521-100mg
Description: 7-BFC (7-Benzyloxy-4-(trifluoromethyl)coumarin) is a coumarin-like fluorescent substrate that serves as a biomarker for cytochrome P 450 and can be used to study CYP isoforms and cytochrome P 450 metabolism. Target: P450. Smiles: FC(F)(F)c1cc(=O)oc2cc(OCc3ccccc3)ccc12. References: A B Renwick, et al....
| Schlagworte: | 7-Benzyloxy-4-(trifluoromethyl)coumarin, Y040-0031 |
| Anwendung: | Fluorogenic CYP1A2 / CYP3A substrate |
| CAS | 220001-53-6 |
| MW: | 320.26 D |
ab 42,00 €
8-hydroxy Loxapine
Artikelnummer: TGM-T37163-1mg
Description: 8-hydroxy Loxapine can be used in related research in the field of life sciences. Its product number is T37163 and CAS number is 61443-77-4. Target: Others. Smiles: ClC=1C=CC=2OC3=CC=C(O)C=C3N=C(C2C1)N4CCN(C)CC4
| Anwendung: | Metabolite |
| CAS | 61443-77-4 |
| MW: | 343.81 D |
ab 381,00 €
5-hydroxy-6-methoxy (S)-Duloxetine
Artikelnummer: TGM-T37211-1mg
Description: 5-hydroxy-6-methoxy (S)-Duloxetine is a metabolite of (S)-duloxetine . It is formed from (S)-duloxetine via a 5- or 6-hydroxy duloxetine intermediate, which is formed by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2D6, and a catechol duloxetine intermediate. 5-hydroxy-6-methoxy (S)-Duloxetine binds...
| Anwendung: | Metabolite |
| CAS | 741693-79-8 |
| MW: | 343.44 D |
657,00 €
6-hydroxy Warfarin
Artikelnummer: TGM-T36725-10mg
Description: 6-Hydroxywarfarin, a metabolite of (+)-warfarin, acts as a weak vitamin K antagonist. Target: Others. Smiles: O=C1OC=2C=CC(O)=CC2C(O)=C1C(C=3C=CC=CC3)CC(=O)C
| Anwendung: | Metabolite |
| CAS | 17834-02-5 |
| MW: | 324.33 D |
ab 119,00 €
Furafylline
Artikelnummer: TGM-T7410-100mg
Description: Furafylline is a selective inhibitor of human cytochrome P450 (CYP)1A2 (IC50 : 0.07 µM),. Target: P450. Smiles: Cc1nc2n(Cc3ccco3)c(=O)n(C)c(=O)c2[nH]1. References: Sesardic D , Boobis A R , Murray B P , et al. Furafylline is a potent and selective inhibitor of cytochrome P450IA2 in man.[J]. British...
| Anwendung: | Selective CYP1A2 inhibitor |
| CAS | 80288-49-9 |
| MW: | 260.25 D |
ab 120,00 €
1,3-Dimethyluric acid
Artikelnummer: TGM-T8075-1mL
Description: 1,3-Dimethyluric acid, a product of theophylline metabolism in man, is one of the purine components in urinary calculi. Target: Endogenous Metabolite. Smiles: Cn1c2[nH]c(=O)[nH]c2c(=O)n(C)c1=O
| Anwendung: | Caffeine / theophylline active metabolite |
| CAS | 944-73-0 |
| MW: | 196.16 D |
30,00 €
(S)-O-Desmethyl Naproxen
Artikelnummer: TGM-T84994-10mg
Description: (S)-O-Desmethyl naproxen, a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (+)-naproxen ((S)-naproxen), is produced through the action of cytochrome P450 (CYP) isoforms CYP1A2 and CYP2C9. Target: Others. Smiles: [C@H](C(O)=O)(C)C1=CC2=C(C=C1)C=C(O)C=C2
| Schlagworte: | (S)-6-Desmethyl Naproxen |
| Anwendung: | (S)-naproxen metabolite |
| CAS | 52079-10-4 |
| MW: | 216.23 D |
Bitte fragen Sie den aktuellen Preis für diesen Artikel an.
Anti-CYP1A2
Artikelnummer: CSB-PA439630.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CYP1A2. Antigen Species: Human
| Schlagworte: | Anti-CYPIA2, Anti-Cytochrome P450 4, Anti-Cytochrome P(3)450, Anti-Cytochrome P450-P3, Anti-Cytochrome P450 1A2,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 167,00 €
Anti-CYP1A2
Artikelnummer: CSB-PA914144.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CYP1A2. Antigen Species: Human
| Schlagworte: | Anti-CYPIA2, Anti-Cytochrome P450 4, Anti-Cytochrome P(3)450, Anti-Cytochrome P450-P3, Anti-Cytochrome P450 1A2,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Isoimperatorin
Artikelnummer: Cay19851-5
Isoimperatorin is a natural furanocoumarin that can be isolated from a variety of plant parts. It inhibits cytochrome P450 (CYP) isoform 1A activity, in particular blocking hepatic ethoxyresorufin O-dealkylase activity. Through its effects on CYP1A, isoimperatorin reduces the metabolism of polycyclic aromatic...
| Schlagworte: | 4-[(3-methyl-2-buten-1-yl)oxy]-7H-furo[3,2-g][1]benzopyran-7-one |
| Anwendung: | CYP1A inhibitor |
| CAS | 482-45-1 |
| MW: | 270.3 D |
ab 44,00 €
Furafylline
Artikelnummer: Cay9000058-5
Furafylline is a selective inhibitor of human cytochrome P450 (CYP)1A2 (IC50 = 0.07 µM), demonstrating little effect on other CYP isoforms including 2D1, 2C, 3A, or 1A1. It was originally introduced as a bronchodilator with extended duration compared to theophylline, but then subsequently reported to inhibit the...
| Schlagworte: | 3-(2-furanylmethyl)-3,9-dihydro-1,8-dimethyl-1H-purine-2,6-dione |
| Anwendung: | Selective CYP1A2 inhibitor |
| CAS | 80288-49-9 |
| MW: | 260.3 D |
ab 111,00 €