Zu "K07408" wurden 76 Artikel gefunden!
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Diosmetin
Artikelnummer: TGM-T1704-100mg
Description: Diosmetin (Luteolin 4-methyl ether) has been found to act as a weak TrkB receptor agonist. Target: Trk receptor, P450. Smiles: O=C1C=2C(OC(=C1)C3=CC(O)=C(OC)C=C3)=CC(O)=CC2O. References: Sher E, et al. Pharmacol Res, 1992, 26(4), 395-402.
| Schlagworte: | Luteolin 4-methyl ether |
| Anwendung: | CYP1A1 inhibitor, CYP1B1 inhibitor |
| CAS | 520-34-3 |
| MW: | 300.26 D |
ab 34,00 €
7-Ethoxyresorufin
Artikelnummer: TGM-T21507-1mg
Description: 7-Ethoxyresorufin (Resorufin ethyl ether) (7-ER) is a fluorometric substrate and competitive inhibitor of cytochrome P450, particularly CYP1A1. Target: NO Synthase, P450. Smiles: CCOc1ccc2nc3ccc(=O)cc3oc2c1. References: C G Li, et al. Inhibition of NO-medicate responses by 7-ethoxyresorufin, a...
| Schlagworte: | Resorufin ethyl ether |
| Anwendung: | Cytochrome P450 1A1 fluorometric substrate / competitive inhibitor |
| CAS | 5725-91-7 |
| MW: | 241.24 D |
ab 31,00 €
Alizarin
Artikelnummer: TGM-T2949-1g
Description: Alizarin (Mordant Red 11), a red dye derived from the roots of plants of the madder genus, inhibits P450 isoform CYP1A1( IC50 = 6.2 µM), CYP1A2 (IC50 =10.0 µM )and CYP1B1(IC50 = 2.7 µM). Target: P450. Smiles: OC1=C(O)C2=C(C=C1)C(=O)C1=CC=CC=C1C2=O. References: Takahashi E, et al. Mutat Res, 2002,...
| Schlagworte: | Mordant Red 11, Anthraquinonic |
| Anwendung: | CYP1A1 / CYP1A2 / CYP1B1 inhibitor |
| CAS | 72-48-0 |
| MW: | 240.21 D |
ab 46,00 €
Isoimperatorin
Artikelnummer: TGM-T2846-100mg
Description: Isoimperatorin is an anti-inflammatory agent, exhibits significant inhibitory effects on acetylcholinesterase (AChE). Target: AChE, Antibacterial. Smiles: CC(C)=CCOc1c2ccoc2cc2oc(=O)ccc12. References: Kim DK, et al. Acetylcholinesterase inhibitors from the roots of Angelica dahurica. Arch Pharm Res....
| Anwendung: | CYP1A inhibitor |
| CAS | 482-45-1 |
| MW: | 270.28 D |
ab 41,00 €
CYP1A1 inhibitor 8a
Artikelnummer: TGM-T27109-100mg
Description: CYP1A1 inhibitor 8a is a potent and selective CYP1A1 inhibitor. It antagonizes B[a]P mediated activation of aromatic hydrocarbon receptor (AhR) in yeast cells, thereby protects human cells from CYP1A1-mediated B[a]P toxicity. Target: Others. Smiles: O(C)C1=C(OC)C(OC)=CC(C=CC(=O)C=2C=CN=CC2)=C1....
| Anwendung: | CYP1A1 inhibitor |
| CAS | 159429-58-0 |
| MW: | 299.32 D |
ab 1.491,00 €
Rhapontigenin
Artikelnummer: TGM-T3776-100mg
Description: Rhapontigenin (Protigenin) is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer...
| Schlagworte: | Protigenin |
| Anwendung: | Resveratrol analog, antioxidant, selective CYP1A1 inactivator |
| CAS | 500-65-2 |
| MW: | 258.27 D |
ab 51,00 €
Dolutegravir M1
Artikelnummer: TGM-T36793-1mg
Description: Dolutegravir M1 is a metabolite of the HIV integrase inhibitor dolutegravir .1It is formed primarily by the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1B1. Target: Others. Smiles: [H][C@]12Cn3cc(C(N)=O)c(=O)c(O)c3C(=O)N1[C@H](C)CCO2. References: Zhu, J., Wang, P., Li, F., et al.CYP1A1 and 1B1-mediated...
| Anwendung: | Dolutegravir metabolite |
| CAS | 1485081-26-2 |
| MW: | 293.279 D |
ab 108,00 €
4'-Hydroxychalcone
Artikelnummer: TGM-T7917-100mg
Description: 4'-Hydroxychalcone (2-Benzal-4-Hydroxyacetophenone) is a chalcone metabolite with hepatoprotective activity. Target: Proteasome. Smiles: OC1=CC=C(C=C1)C(=O)\C=C\C1=CC=CC=C1. References: Orlikova B , Tasdemir D , Golais F , et al. The aromatic ketone 4'-hydroxychalcone inhibits TNFalpha-induced NF-kappaB...
| Schlagworte: | 2-Benzal-4-Hydroxyacetophenone |
| Anwendung: | Chalcone metabolite |
| CAS | 2657-25-2 |
| MW: | 224.25 D |
ab 47,00 €
3-Cyano-7-ethoxycoumarin
Artikelnummer: TGM-T7696-10mg
Description: 3-Cyano-7-ethoxycoumarin is cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2 . Target: Others. Smiles: CCOc1ccc2cc(C#N)c(=O)oc2c1. References: White I N H . A continuous fluorometric assay for cytochrome P-450-dependent mixed function oxidases using 3-cyano-7-ethoxycoumarin[J]. Analytical Biochemistry,...
| Anwendung: | Fluorogenic probe, CYP1A1 / CYP1A2 probe |
| CAS | 117620-77-6 |
| MW: | 215.2 D |
ab 50,00 €
7-Ethoxy-4-Methylcoumarin
Artikelnummer: TGM-T8038-200mg
Description: 7-Ethoxy-4-Methylcoumarin is considered an inhibitor of enzymes in cells and has been used in studies of enzyme inhibition and has been used to study the effects of various drugs on the human body. Target: Others. Smiles: CCOC1=CC=C2C(C)=CC(=O)OC2=C1. References: Krzysztof Zamojc, Wieslaw Wiczk,...
| Anwendung: | CYP1A1 / CYP2B4 / CYP2B6 activity monitoring, fluorophore |
| CAS | 87-05-8 |
| MW: | 204.22 D |
30,00 €
CYP1A1 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-01182-100ug
Description: CYP1A1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 63.7 kDa and the accession number is P04798.
| Schlagworte: | CYPIA1, CYP1A1, Hydroperoxy icosatetraenoate dehydratase, Cytochrome P450 1A1, Cytochrome P450-P1, Cytochrome P450-C,... |
| MW: | 63.7 kD |
ab 278,00 €
Diosmetin-d3
Artikelnummer: TGM-TMIJ-0493-1mg
Description: Diosmetin-d3 is a deuterated compound of Diosmetin. Diosmetin has a CAS number of 520-34-3. Diosmetin has been found to act as a weak TrkB receptor agonist. Smiles: O1C(=CC(C2=C(C=C(C=C12)O)O)=O)C1C=CC(=C(C=1)O)OC([2H])([2H])[2H]
| Anwendung: | GC-MS, LC-MS, internal standard, CYP1A1 inhibitor, CYP1B1 inhibitor |
| CAS | 1189728-54-8 |
| MW: | 303.28 D |
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