Zu "K07376" wurden 52 Artikel gefunden!
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PRKG1 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPJ-01112-10ug
Description: cGMP-Dependent Protein Kinase 1 (PRKG1) belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. PRKG1 contains one AGC-kinase C-terminal domain, two cyclic nucleotide-binding domains, and one protein kinase domain. PRKG1 is mainly expressed in the lung and placenta. PRKG1 acts...
| Schlagworte: | PRKG1B, cGKI, PRKGR1B, cGMP-Dependent Protein Kinase I, PRKGR1A, PRKG1, cGK1, cGK 1, cGMP-Dependent Protein Kinase 1 |
| MW: | 75 kD |
ab 180,00 €
Protein kinase G inhibitor-2
Artikelnummer: TGM-T9940-100mg
Description: Protein kinase G inhibitor-2 exhibits antibacterial, antiviral, and antitumor activities. Target: Others. Smiles: C(N)(=O)C=1C2=C(SC1NC(=O)C3CCC3)CCCC2. References: Koul Anil, et al. Heterobicyclic compounds as pharmaceutically active agents. WO2005023818A2
| Anwendung: | Protein kinase G (cGMP-dependent protein kinase) inhibitor |
| CAS | 612829-80-8 |
| MW: | 278.37 D |
ab 33,00 €
PKG inhibitor peptide
Artikelnummer: TGM-TP1903-1mg
Description: Competitive inhibitor of cGMP-dependent protein kinase (PKG), analog of a substrate peptide corresponding to a phosphorylation site of histone H2B. Competes with synthetic substrates (Ki = 86 mM) but does not inhibit phosphorylation of intact histones by PKG. Inhibits phosphorylation of intact histones...
| Schlagworte: | cGMP Dependent Kinase Inhibitor Peptide |
| Anwendung: | cGMP-dependent protein kinase (PKG) inhibitor |
| CAS | 82801-73-8 |
| MW: | 943.12 D |
ab 140,00 €
Protein kinase G inhibitor-1
Artikelnummer: TGM-T67755-100mg
Description: Protein kinase G inhibitor-1 is a potent Protein kinase G inhibitor, IC50= 0.9 uM. Target: PKA. Smiles: C(N)(=O)C=1C2=C(SC1NC(=O)C3CC3)CC(C)CC2. References: Pato, Janos, United States, US20040171603 A1 2004-09-02, CAplus
| Anwendung: | Protein kinase G inhibitor |
| CAS | 354544-70-0 |
| MW: | 278.37 D |
ab 190,00 €
8-Bromo-cGMP sodium
Artikelnummer: TGM-T14064-10mg
Description: 8-Bromo-cGMP sodium is a PKG activator, a membrane-permeable analog of cGMP. 8-Bromo-cGMP sodium has pain-relieving and vasodilatory effects, significantly inhibits Ca2+ macroscopic currents, and inhibits high K+-stimulated insulin release. Target: Calcium Channel, PKA. Smiles:...
| Anwendung: | Cell-permeable cGMP analog, PRKG activator |
| CAS | 51116-01-9 |
| MW: | 446.09 D |
ab 54,00 €
KT5823
Artikelnummer: TGM-T15670-1mg
Description: KT5823 is a selective and potent cGMP-dependent protein kinase (PKG) inhibitor with inhibitory effects on PKA and PKC.KT5823 increases thyroid-stimulating hormone-induced (Na+/I- symporter) NIS expression and iodide ion uptake by modulating sodium iodide symporter protein expression and activity in...
| Anwendung: | PKG inhibitor |
| CAS | 126643-37-6 |
| MW: | 495.53 D |
3.141,00 €
PKG drug G1
Artikelnummer: TGM-T4661-100mg
Description: PKG drug G1 targets PKG Ialpha C42. PKG drug G1 can couple to vasodilation and blood pressure lowering by a C42 PKG Ialpha-independent mechanism. Target: PKA. Smiles: Cc1[nH]c2ccccc2c1\C=C1/NC(=S)NC1=O. References: Burgoyne JR, et al. Proof of Principle for a Novel Class of Antihypertensives That Target...
| Anwendung: | Protein kinase Gialpha activator |
| CAS | 374703-78-3 |
| MW: | 257.31 D |
ab 33,00 €
GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD
Artikelnummer: TGM-T5065-100mg
Description: GUANOSINE 3':5'-CYCLIC MONOPHOSPH ATESOD (cGMP sodium salt) , also known as cGMP, is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin. GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE...
| Schlagworte: | Monosodium-GMP, cGMP sodium salt, Cyclic GMP |
| Anwendung: | PKG activator |
| CAS | 40732-48-7 |
| MW: | 367.19 D |
ab 51,00 €
cGMP-dependent protein kinase 1 (Prkg1), mouse, recombinant
Artikelnummer: CSB-EP018715MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 2-671aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: SELEEDFAKI LMLKEERIKE LEKRLSEKEE EIQELKRKLH KCQSVLPVPS THIGPRTTRA QGISAEPQTY RSFHDLRQAF RKFTKSERSK...
| Schlagworte: | cGKI, cGK1, Prkg1, cGK 1, Prkg1b, EC=2.7.11.12, cGMP-dependent protein kinase 1, cGMP-dependent protein kinase I,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 83.7 kD |
ab 354,00 €
KT 5823
Artikelnummer: Cay10010965-100
The activity of cGMP-dependent protein kinase (PKG) is controlled by factors that elevate cellular cGMP, like nitric oxide (NO), and by those that reduce cGMP levels, like certain phosphodiesterases. KT 5823 is a potent, selective inhibitor of cGMP-dependent protein kinase (PKG) (in vitro IC50 = 234 nM). KT 5823 is...
| Schlagworte: | 2,3,9,10,11,12-hexahydro-10R-methoxy-2,9-dimethyl-1-oxo-9S,12R-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]b... |
| Anwendung: | PKG inhibitor |
| CAS | 126643-37-6 |
| MW: | 495.5 D |
ab 50,00 €
8-bromo Cyclic GMP (sodium salt)
Artikelnummer: Cay15992-5
8-bromo Cyclic GMP (8-bromo cGMP) is a cell-permeable analog of cGMP that exhibits greater resistance to hydrolysis by phosphodiesterases than its parent compound. It preferentially activates cGMP-dependent protein kinase. At 1 µM-0.1 mM, 8-bromo cGMP can inhibit acetylcholine-induced increases in intracellular...
| Schlagworte: | 8-bromo-cGMP, 8-bromo Guanosine 3',5'-cyclic monophosphate, 8-bromo-guanosine cyclic 3',5'-(hydrogen phosphate),... |
| Anwendung: | Cell-permeable cGMP analog, PRKG activator |
| CAS | 51116-01-9 |
| MW: | 447.1 D |
ab 60,00 €
PKG Inhibitor
Artikelnummer: Cay15995-1
PKG inhibitor is a specific cGMP-dependent PKG inhibitor (Ki = 86 µM). This synthetic peptide is a nonphosphorylatable analog of a substrate corresponding to the serine-32 phosphorylation site in histone H2B. PKG inhibitor has been reported to block cGMP-dependent NMDA potentiation and nitric oxide-induced...
| Schlagworte: | Arginyl-lysyl-arginyl-alanyl-arginyl-lysyl-glutamic acid, Protein Kinase G Inhibitor,... |
| Anwendung: | cGMP-dependent protein kinase (PKG) inhibitor |
| CAS | 82801-73-8 |
| MW: | 943.1 D |
ab 77,00 €