Zu "K07363" wurden 41 Artikel gefunden!
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ITK inhibitor
Artikelnummer: TGM-T37604-100mg
Description: Interleukin-2-inducible T cell kinase (ITK) is a non-receptor tyrosine kinase expressed in T cells, NKT cells and mast cells which plays a crucial role in regulating the T cell receptor (TCR), CD28, CD2, chemokine receptor CXCR4, and FcepsilonR-mediated signaling pathways. ITK inhibitors can be used for...
| Anwendung: | ITK inhibitor |
| CAS | 439574-61-5 |
| MW: | 609.8 D |
ab 1.822,00 €
ITK inhibitor 5
Artikelnummer: TGM-T61854-100mg
Description: ITK inhibitor 5 (compound 27) is a highly potent and selective ITK inhibitor, demonstrating IC50 values of 5.6 nM for ITK and 25 nM for BTK [1]. Target: Others. Smiles: O(CCNC(C=C)=O)C1=C2C=C(C=3C=4C(NN3)=CC(C(F)F)=CC4)NC2=CC=C1
| Anwendung: | ITK inhibitor |
| CAS | 2404603-41-2 |
| MW: | 396.39 D |
ab 1.521,00 €
ITK inhibitor 6
Artikelnummer: TGM-T63229-100mg
Description: ITK inhibitor 6 is a selective and potent ITK inhibitor that acts on ITK (IC50: 4 nM), BTK (IC50: 133 nM), JAK3 (IC50: 320 nM), EGFR (IC50: 2360 nM), LCK (IC50: 155 nM). ITK inhibitor 6 inhibited the phosphorylation of PLCgamma1 and ERK1/2 and showed anti-proliferative effect. Target: Others. Smiles:...
| Anwendung: | ITK inhibitor |
| CAS | 2404604-06-2 |
| MW: | 486.51 D |
ab 1.521,00 €
ITK Protein, Human, Recombinant (Actived By LCK, GST)
Artikelnummer: TGM-TMPY-05249-50ug
Description: ITK Protein, Human, Recombinant (Actived By LCK, GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 57.7 kDa and the accession number is Q08881.
| Schlagworte: | EMT, IL2-inducible T-cell kinase, LPFS1, PSCTK2, LYK |
| MW: | 57.7 kD |
497,00 €
ITK Protein, Mouse, Recombinant (aa 351-619, His & GST)
Artikelnummer: TGM-TMPY-04570-50ug
Description: ITK Protein, Mouse, Recombinant (aa 351-619, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 58.4 kDa and the accession number is Q03526.
| Schlagworte: | IL2-inducible T-cell kinase, Tsk, Emt, Tcsk |
| MW: | 58.4 kD |
397,00 €
ITK inhibitor 2
Artikelnummer: TGM-T11690-100mg
Description: ITK inhibitor 2 is an interleukin-2-inducible T-cell kinase (ITK) inhibitor with an IC50 of 2 nM. Target: JAK. Smiles: CC1(C)CC2=C(C(=NN2)C=3NC=4C(C3)=CC=C(N(C([C@H](C)N5CCOCC5)=O)C)C4)CC1. References: Teruhiko Inoue, et al. Indole compounds and their pharmaceutical use.
| Anwendung: | ITK inhibitor |
| CAS | 1309784-09-5 |
| MW: | 435.56 D |
ab 803,00 €
Anti-Phospho-ITK (Y512)
Artikelnummer: CSB-PA011277.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-EMT, Anti-phospho-ITK, Anti-phospho-Kinase EMT, EC=2.7.10.2, Anti-phospho-T-cell-specific kinase,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 126,00 €
Anti-ITK
Artikelnummer: CSB-PA087882.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ITK. Antigen Species: Human
| Schlagworte: | Anti-EMT, Anti-ITK, Anti-Kinase EMT, EC=2.7.10.2, Anti-T-cell-specific kinase, Anti-Tyrosine-protein kinase Lyk,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Anti-ITK / IL2-inducible T-cell kinase
Artikelnummer: NSJ-RQ7513
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Tyrosine-protein kinase ITK/TSK, also known as interleukin-2-inducible T-cell kinase or simply ITK, is a protein that in humans is encoded by the ITK gene. It is a member of the TEC family of kinases. This gene is mapped to 5q33.3. This gene encodes an...
| Schlagworte: | Anti-EMT, Anti-ITK, Anti-Kinase EMT, EC=2.7.10.2, Anti-T-cell-specific kinase, Anti-Tyrosine-protein kinase Lyk,... |
| Anwendung: | WB, IHC (paraffin), FC, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
772,00 €
ITK, active human recombinant protein
Artikelnummer: BPS-40445
Active recombinant human ITK (352-end) was expressed in Sf9 cells using an N-terminal GST tag. The gene accession number is NM_005546.
| Schlagworte: | EMT, ITK, Kinase EMT, EC=2.7.10.2, T-cell-specific kinase, Tyrosine-protein kinase Lyk, IL-2-inducible T-cell kinase,... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 57 kD |
536,00 €
Anti-ITK, C-terminal
Artikelnummer: ARG63136.100
Protein function: Tyrosine kinase that plays an essential role in regulation of the adaptive immune response. Regulates the development, function and differentiation of conventional T-cells and nonconventional NKT-cells. When antigen presenting cells (APC) activate T-cell receptor (TCR), a series of phosphorylation...
| Schlagworte: | Anti-ITK, Anti-EMT, Anti-Kinase EMT, EC=2.7.10.2, Anti-T-cell-specific kinase, Anti-Tyrosine-protein kinase Lyk,... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
822,00 €
ITK(Lyk), active murine recombinant, N-terminal GST-tag
Artikelnummer: BPS-40446
Active murine recombinant IL2-inducible T-cell kinase (ITK), also known as Lyk and TSK (GenBank Accession #NM_010583),a.a. 352-620(end) with N-terminal GST-tag, MW= 57 kDa, expressed in Sf9 cells via abaculovirus expression system.
| Schlagworte: | Emt, Itk, Kinase EMT, Kinase TLK, EC=2.7.10.2, T-cell-specific kinase, IL-2-inducible T-cell kinase, Tyrosine-protein... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| MW: | 57 kD |
536,00 €