Zu "K07209" wurden 132 Artikel gefunden!
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NEU
Inhibitor of nuclear factor kappa-B kinase subunit beta...
Artikelnummer: CSB-BP011572HU.1
Organism: Homo sapiens (Human). Source: Baculovirus. Expression Region: 1-756aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MSWSPSLTTQ TCGAWEMKER LGTGGFGNVI RWHNQETGEQ IAIKQCRQEL SPRNRERWCL EIQIMRRLTH PNVVAARDVP EGMQNLAPND LPLLAMEYCQ GGDLRKYLNQ FENCCGLREG AILTLLSDIA...
| Schlagworte: | IKK2, IKKB, IkBKB, IKK-B, IKBKB, NFKBIKB, IKK-beta, EC=2.7.11.10, I-kappa-B kinase 2, I-kappa-B-kinase beta,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
| MW: | 89.1 kD |
ab 474,00 €
NEU
Inhibitor of nuclear factor kappa-B kinase subunit beta...
Artikelnummer: CSB-EP011572HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-756aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MSWSPSLTTQ TCGAWEMKER LGTGGFGNVI RWHNQETGEQ IAIKQCRQEL SPRNRERWCL EIQIMRRLTH PNVVAARDVP EGMQNLAPND LPLLAMEYCQ GGDLRKYLNQ FENCCGLREG AILTLLSDIA...
| Schlagworte: | IKK2, IKKB, IkBKB, IKK-B, IKBKB, NFKBIKB, IKK-beta, EC=2.7.11.10, I-kappa-B kinase 2, I-kappa-B-kinase beta,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 92.5 kD |
ab 283,00 €
NEU
Anti-IKBKB
Artikelnummer: CSB-PA003010.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-IKK2, Anti-IKKB, Anti-IkBKB, Anti-IKBKB, Anti-IKK-B, Anti-NFKBIKB, Anti-IKK-beta, EC=2.7.11.10, Anti-I-kappa-B kinase... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
NEU
Anti-IKBKB
Artikelnummer: CSB-PA16309A0Rb.50
Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: IKBKB. Antigen Species: Human
| Schlagworte: | Anti-IKK2, Anti-IKKB, Anti-IkBKB, Anti-IKBKB, Anti-IKK-B, Anti-NFKBIKB, Anti-IKK-beta, EC=2.7.11.10, Anti-I-kappa-B kinase... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
| MW: | 87 kD |
ab 163,00 €
Mouse IKKB (Inhibitor of kappa B Kinase Beta) ELISA Kit
Artikelnummer: ELK-ELK0724.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse IKKB. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse IKKB. Next,...
| Schlagworte: | IKK2, Ikkb, IkBKB, Ikbkb, IKK-B, NFKBIKB, IKK-beta, I-kappa-B kinase 2, I-kappa-B-kinase beta, Serine/threonine protein... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
BMS 345541 (hydrochloride)
Artikelnummer: Cay16667-1
BMS 345541 is a cell permeable inhibitor of the IkappaB kinases IKKalpha and IKKbeta (IC50s = 4 and 0.3 µM). It is without effect against a panel of other serine/threonine and tyrosine kinases at 100 µM. BMS 345541 inhibits signaling through nuclear factor-kappaB (NF-kappaB) both in cells and in vivo, showing...
| Schlagworte: | IKK Inhibitor III, N1-(1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl)-1,2-ethanediamine, bis(2,2,2-trifluoroacetate) |
| Anwendung: | Cell permeable IKK-alpha/beta inhibitor |
| CAS | 547757-23-3 |
| MW: | 291.8 D |
ab 60,00 €
COVID-19 Forschung
Auranofin
Artikelnummer: AG-CR1-3611-M025
White to off-white solid. Soluble in DMSO or 100% ethanol. Insoluble in water. Anti-inflammatory and anti-arthritic agent. Represses the activation of the NLRP3/IL-1beta pathway, Inhibitor of 5-lipoxygenase in human neutrophils, IKB kinase (IKK) by modifying Cys-179 of the IKKbeta subunit 5, Potent thioredoxin...
| Schlagworte: | 1-Thio-beta-D-glucopyranosatotriethylphosphine gold-2,3,4,6-tetra- acetate, NSC 321521, SKF 39162 |
| Anwendung: | Antiinflammatory agent |
| CAS | 34031-32-8 |
| MW: | 678,5 D |
ab 61,00 €
IKK-16 (hydrochloride)
Artikelnummer: Cay13313-5
IKK-16 is a potent inhibitor of IkappaB kinases (IKKs), displaying IC50 values of 200, 40, and 70 nM for IKKalpha, IKKbeta, and IKK complex, respectively, in cell-free assays. It is effective in cells and in animals and has been used delineate the role of NF-kappaB signaling in diverse contexts. IKK-16 has also been...
| Schlagworte: | IKK Inhibitor VII, [4-[(4-benzo[b]thien-2-yl-2-pyrimidinyl)amino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]-methanone,... |
| Anwendung: | IkappaB kinase inhibitor |
| CAS | 1186195-62-9 |
| MW: | 520.1 D |
ab 125,00 €
BI-605906
Artikelnummer: Cay19184-1
BI-605906 is an inhibitor of inhibitor of kappa B kinase subunit beta (IKKbeta, IC50 = 380 nM). It is selective for IKKbeta over insulin-like growth factor 1 (IGF1, IC50 = 7.6 µM) and over 100 kinases in a panel up to 10 µM. BI-605906 partially inhibits IL-1-stimulated activation of IKKepsilon/TBK1 in vitro....
| Schlagworte: | 3-amino-4-(1,1-difluoropropyl)-6-[4-(methylsulfonyl)-1-piperidinyl]-thieno[2,3-b]pyridine-2-carboxamide |
| Anwendung: | IKK beta inhibitor |
| CAS | 960293-88-3 |
| MW: | 432.5 D |
ab 102,00 €
SC-514
Artikelnummer: Cay10010267-10
SC-514 is a selective and reversible inhibitor of IkappaB kinase 2 (IKK2) (IC50 = 3-12 µM) that displays greater than 10-fold selectivity over 28 other kinases, including JNK, p38, MK2, and ERK. In synovial fibroblasts stimulated with interleukin (IL)-1beta, SC-514 attenuates NF-kappaB-mediated expression of IL-6,...
| Schlagworte: | 4-amino-[2,3'-bithiophene]-5-carboxamide |
| Anwendung: | IKK2 inhibitor |
| CAS | 354812-17-2 |
| MW: | 224.3 D |
ab 60,00 €
Anti-IKKbeta, clone 10AG2
Artikelnummer: 200-301-H83
Anti-IKKbeta Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with IKKbeta from Human and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity withAnti-IKKbeta from other sources has not been determined. Protein function: Serine kinase...
| Schlagworte: | Anti-IKK2, Anti-IKKB, Anti-IKBKB, Anti-IKK-B, Anti-IkBKB, Anti-NFKBIKB, Anti-IKK-beta, EC=2.7.11.10, Anti-I-kappa-B kinase... |
| Anwendung: | FC, IHC, IP, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse |
791,00 €
IMD 0354
Artikelnummer: Cay17290-1
IMD 0354 is an IKKbeta (IKK2) inhibitor that blocks NF-kappaB phosphorylation (IC50 = ~250 nM) and subsequent NF-kappaB p65 nuclear translocation. It exhibits cardioprotective properties by decreasing expression of P-selectin and ICAM-1 in the vasculature and blocking cardiomyocyte IL-1beta and MCP-1 production,...
| Schlagworte: | IKK2 Inhibitor V, N-[3,5-bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxy-benzamide |
| Anwendung: | IKK2 inhibitor |
| CAS | 978-62-1 |
| MW: | 383.7 D |
ab 50,00 €