Zu "K07203" wurden 176 Artikel gefunden!
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Rapamycin
Artikelnummer: Cay13346-1
Rapamycin is an allosteric inhibitor of the mammalian target of rapamycin (mTOR) complex 1 (mTORC1) originally isolated from S. hygroscopicus. It interacts with FKBP prolyl isomerase 1A (FKBP12) to form a complex that binds to and inhibits the kinase activity of mTORC1. Rapamycin inhibits growth of Rh1 and Rh30...
| Schlagworte: | AY 22989, NSC 226080, Wy 090217,... |
| Anwendung: | mTORC1 blocking |
| CAS | 53123-88-9 |
| MW: | 914.2 D |
ab 50,00 €
Torin 1
Artikelnummer: Cay10997-10
Torin 1 is a potent and selective inhibitor of mTOR (IC50 = 2 and 10 nM for mTORC1 and mTORC2, respectively). It shows over 100-fold selectivity for mTOR over PI3Kalpha and other PI3K-like kinases, including ATM, DNA-PK, and hVps34, as well as 450 other protein kinases. Torin 1, is efficacious at a dose of 20 mg/kg...
| Schlagworte: | 1-[4-[4-(1-oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)-benzo[h]-1,6-naphthyridin-2(1H)-one |
| Anwendung: | mTor inhibitor |
| CAS | 1222998-36-8 |
| MW: | 607.6 D |
ab 196,00 €
Serine/threonine-protein kinase mTOR (MTOR), partial,...
Artikelnummer: CSB-EP008968HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 2012-2144aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: VSEELIRVAI LWHEMWHEGL EEASRLYFGE RNVKGMFEVL EPLHAMMERG PQTLKETSFN QAYGRDLMEA QEWCRKYMKS GNVKDLTQAW DLYYHVFRRI SKQLPQLTSL...
| Schlagworte: | MTOR, FRAP, mTOR, Rapamycin target protein 1, Rapamycin and FKBP12 target 1, Mammalian target of rapamycin, Mechanistic... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 23.2 kD |
ab 240,00 €
Anti-MTOR
Artikelnummer: CSB-PA003333.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-MTOR, Anti-FRAP, Anti-mTOR, Anti-Rapamycin target protein 1, Anti-Rapamycin and FKBP12 target 1, Anti-Mammalian... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
Anti-MTOR
Artikelnummer: CSB-PA008481.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-MTOR, Anti-FRAP, Anti-mTOR, Anti-Rapamycin target protein 1, Anti-Rapamycin and FKBP12 target 1, Anti-Mammalian... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
106,00 €
Anti-Phospho-MTOR (S2448)
Artikelnummer: CSB-PA000576.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-MTOR, Anti-phospho-FRAP, Anti-phospho-mTOR, Anti-phospho-Rapamycin target protein 1, Anti-phospho-Rapamycin... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
Anti-Phospho-MTOR (T2446)
Artikelnummer: CSB-PA000652.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-MTOR, Anti-phospho-FRAP, Anti-phospho-mTOR, Anti-phospho-Rapamycin target protein 1, Anti-phospho-Rapamycin... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
Anti-MTOR (Ab-2481)
Artikelnummer: CSB-PA054657.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
| Schlagworte: | Anti-MTOR, Anti-FRAP, Anti-mTOR, Anti-Rapamycin target protein 1, Anti-Rapamycin and FKBP12 target 1, Anti-Mammalian... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
275,00 €
Anti-MTOR (Ab-2448)
Artikelnummer: CSB-PA208208.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
| Schlagworte: | Anti-MTOR, Anti-FRAP, Anti-mTOR, Anti-Rapamycin target protein 1, Anti-Rapamycin and FKBP12 target 1, Anti-Mammalian... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
275,00 €
Anti-Phospho-MTOR (Ser2448)
Artikelnummer: CSB-PA271384.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
| Schlagworte: | Anti-phospho-MTOR, Anti-phospho-FRAP, Anti-phospho-mTOR, Anti-phospho-Rapamycin target protein 1, Anti-phospho-Rapamycin... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
330,00 €
Anti-MTOR
Artikelnummer: CSB-PA273227.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: MTOR. Antigen Species: Human
| Schlagworte: | Anti-MTOR, Anti-FRAP, Anti-mTOR, Anti-Rapamycin target protein 1, Anti-Rapamycin and FKBP12 target 1, Anti-Mammalian... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
Anti-MTOR
Artikelnummer: CSB-PA876444.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: MTOR. Antigen Species: Human
| Schlagworte: | Anti-MTOR, Anti-FRAP, Anti-mTOR, Anti-Rapamycin target protein 1, Anti-Rapamycin and FKBP12 target 1, Anti-Mammalian... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €