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Betulin
Betulin

Artikelnummer: TGM-T3121-100mg

Description: Betulin (betulinol) (lup-20(29)-ene-3beta, 28-diol) is an abundant, naturally occurring triterpene. It is commonly isolated from the bark of birch trees where it forms up to 30% of the dry weight of the extractive and is found in birch sap as well. Target: Lipid, Apoptosis, Endogenous Metabolite,...
Schlagworte: Betulol, betulinol, betuline, betulinic alcohol, Trochol
Anwendung: Specific SREBP inhibitor
CAS 473-98-3
MW: 442.72 D
ab 49,00 €
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Fatostatin hydrobromide
Fatostatin hydrobromide

Artikelnummer: TGM-T6832-100mg

Description: Fatostatin hydrobromide (Fatostatin A HBr) ia an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2. Target: NPC1L1, Fatty Acid Synthase. Smiles: Br.CCCc1cc(ccn1)-c1nc(cs1)-c1ccc(C)cc1. References: Kamisuki S, et al. Chem Biol. 2009,...
Schlagworte: Fatostatin, Fatostatin A, Fatostatin A HBr, Fatostatin HBr
Anwendung: SREBP activation inhibitor
CAS 298197-04-3
MW: 375.33 D
ab 43,00 €
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Anti-SREBF1
Anti-SREBF1

Artikelnummer: CSB-PA004153.100

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: Anti-BHLHD1, ADD 1 antibody, bHLHd1 antibody, Class D basic helix-loop-helix protein 1 antibody, D630008H06 antibody,...
Anwendung: ELISA, WB, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, rat
ab 126,00 €
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Anti-SREBF1
Anti-SREBF1

Artikelnummer: CSB-PA005992.50

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: Anti-BHLHD1, ADD 1 antibody, bHLHd1 antibody, Class D basic helix-loop-helix protein 1 antibody, D630008H06 antibody,...
Anwendung: ELISA, WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
126,00 €
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Anti-SREBF1
Anti-SREBF1

Artikelnummer: CSB-PA384481.100

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: Anti-BHLHD1, ADD 1 antibody, bHLHd1 antibody, Class D basic helix-loop-helix protein 1 antibody, D630008H06 antibody,...
Anwendung: ELISA, WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 126,00 €
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Anti-SRPX2
Anti-SRPX2

Artikelnummer: 600-401-EV1

Anti-SRPX2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with SRPX2 from other sources has not been determined. Protein function: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the...
Schlagworte: Anti-BHLHD1, Anti-SREBF1
Anwendung: ELISA, IHC, IFM, WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
834,00 €
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Fatostatin (hydrobromide)
Fatostatin (hydrobromide)

Artikelnummer: Cay13562-10

Sterol regulatory element binding proteins (SREBPs) are transcription factors that have pivotal roles in lipogenesis and fat metabolism. The activation of SREBPs requires escort to the Golgi by SREBP cleavage-activating protein (SCAP) followed by proteolytic release of SREBP from the Golgi. Fatostatin is an...
Schlagworte: 125B11, 4-[4-(4-methylphenyl)-2-thiazolyl]-2-propyl-pyridine, hydrobromide
Anwendung: SREBP activation inhibitor
CAS 298197-04-3
MW: 375.3 D
ab 94,00 €
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Betulin
Betulin

Artikelnummer: AG-CN2-0476-G001

White solid. Soluble in DMSO, DMF or ethanol. Specific SREBPs (sterol regulatory element-binding proteins) inhibitor. Inhibits ER-Golgi translocation of SREBPs through binding to SCAP in an INSIG-dependent manner, Improves hyperlipidemia and insulin resistance and reduces atherosclerotic plaques. Lowers cholesterol...
Schlagworte: Betulinol, Trochol, NSC 4644
Anwendung: Specific SREBP inhibitor
CAS 473-98-3
MW: 442,7 D
ab 55,00 €
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Anti-SREBP1
Anti-SREBP1

Artikelnummer: ARG40316.50

Protein function: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway. Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding...
Schlagworte: Anti-BHLHD1, Anti-SREBF1
Anwendung: IHC (paraffin), WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
567,00 €
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Anti-SREBP1, clone SREBP1/1578
Anti-SREBP1, clone SREBP1/1578

Artikelnummer: NSJ-V8099-100UG

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. The low density lipoprotein (LDL) receptor mediates the endocytic uptake of cholesterol-carrying lipoproteins, thereby controlling cholesterol levels in cells and plasma. Transcription of the LDL receptor gene is controlled by a ten base pair sequence in...
Schlagworte: Anti-BHLHD1, SREBP1 Antibody
Anwendung: IHC (paraffin)
Wirt: Mouse
Spezies-Reaktivität: human
ab 361,00 €
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Anti-SREBP1, clone SREBP1/1578
Anti-SREBP1, clone SREBP1/1578

Artikelnummer: NSJ-V8099SAF-100UG

1 mg/ml in 1X PBS, BSA free, sodium azide free. The low density lipoprotein (LDL) receptor mediates the endocytic uptake of cholesterol-carrying lipoproteins, thereby controlling cholesterol levels in cells and plasma. Transcription of the LDL receptor gene is controlled by a ten base pair sequence in the 5'...
Schlagworte: Anti-BHLHD1, SREBP1 Antibody
Anwendung: IHC (paraffin)
Wirt: Mouse
Spezies-Reaktivität: human
781,00 €
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SREBP-1 (Phospho-Ser439) Colorimetric Cell-Based ELISA Kit
SREBP-1 (Phospho-Ser439) Colorimetric Cell-Based ELISA Kit

Artikelnummer: G-CBCAB01690.96

SREBP-1 (Phospho-Ser439) Colorimetric Cell-Based ELISA Kit Protein function: [Sterol regulatory element-binding protein 1]: Precursor of the transcription factor form (Processed sterol regulatory element- binding protein 1), which is embedded in the endoplasmic reticulum membrane (PubMed:32322062). Low sterol...
Schlagworte: BHLHD1
Anwendung: In-cell ELISA
1.027,00 €
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