Zu "K06745" wurden 408 Artikel gefunden!
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BMS-8
Artikelnummer: TGM-T26859-1mg
Description: BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 µM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers. Target: PD-1/PD-L1. Smiles: Cc1c(COc2ccc(CN3CCCCC3C(O)=O)cc2Br)cccc1-c1ccccc1. References: Gaudy-Marqueste C, Dussouil AS, Carron R, Troin L, Malissen N,...
| Anwendung: | PD-1/PD-L1 interaction inhibitor, PD-L1 dimerization inhibitor |
| CAS | 1675201-90-7 |
| MW: | 494.42 D |
ab 33,00 €
LH1307
Artikelnummer: TGM-T36047-10mg
Description: LH1307 is an inhibitor of the interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 that has an IC50 value of 3 nM in a homologous time-resolved fluorescence (HTRF) assay.1 It increases the activation of Jurkat cells expressing PD-1 in co-culture with U2OS or CHO cells expressing PD-L1...
| Anwendung: | PD-1 - PD-L1 interaction inhibitor |
| CAS | 2375720-38-8 |
| MW: | 915.108 D |
ab 228,00 €
BMS-202
Artikelnummer: TGM-T3146-100mg
Description: BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction. Target: PD-1/PD-L1, Apoptosis. Smiles: COc1nc(OCc2cccc(c2C)-c2ccccc2)ccc1CNCCNC(C)=O. References: Louis S. Chupak, et al. Compounds useful as...
| Schlagworte: | PD1-PDL1 inhibitor 2, PD-1/PD-L1 inhibitor 2 |
| Anwendung: | PDCD1 / CD274 interaction inhibitor |
| CAS | 1675203-84-5 |
| MW: | 419.52 D |
ab 56,00 €
BMS-1
Artikelnummer: TGM-T3655-100mg
Description: BMS-1 (PD-1/PD-L1 inhibitor 1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene and the upregulation of PD-L1 allows Ys to evade the host immune system. High tumor...
| Schlagworte: | PD-1/PD-L1 inhibitor 1, PD1-PDL1 inhibitor 1 |
| Anwendung: | PDCD1 /CD274 protein-protein interaction inhibitor |
| CAS | 1675201-83-8 |
| MW: | 475.58 D |
ab 48,00 €
PD-1/PD-L1-IN-NP19
Artikelnummer: TGM-T36900-100mg
Description: PD-1/PD-L1-IN-NP19, a PD-1/PD-L1 inhibitor, exhibits an IC50 of 12.5 nM against the human PD-1/PD-L1 interaction, potentially activating the tumor immune microenvironment and contributing to its antitumor effects[1]. Target: PD-1/PD-L1. Smiles:...
| Schlagworte: | PD-1/PD-L1-IN-NP19 |
| Anwendung: | PD-1/PD-L1 interaction inhibitor |
| CAS | 2377916-66-8 |
| MW: | 555.06 D |
ab 368,00 €
PD-L1 Protein, Canine, Recombinant (hFc)
Artikelnummer: TGM-TMPY-00237-100ug
Description: PD-L1 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.5 kDa and the accession number is A0A8C0MRV9.
| Schlagworte: | CD274 molecule |
| MW: | 51.5 kD |
ab 378,00 €
PD-L1 Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPY-01155-100ug
Description: PD-L1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is Q3U472.
| Schlagworte: | Pdcd1lg1, Pdl1, A530045L16Rik, CD274 molecule, B7h1, Pdcd1l1 |
| MW: | 26.3 kD |
191,00 €
PD-L1 Protein, Cynomolgus, Recombinant (hFc)
Artikelnummer: TGM-TMPJ-00637-10ug
Description: PD-L1 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 73 KDa and the accession number is G7PSE7.
| Schlagworte: | B7H1, programmed cell death 1 ligand 1, PDL1, CD274 molecule, CD274, PDCD1L1, B7-H1, PDL1PDCD1 ligand 1, PDCD1LG1, CD274... |
| MW: | 73 kD |
ab 108,00 €
PD-L1 Protein, Cynomolgus, Recombinant (His)
Artikelnummer: TGM-TMPJ-00638-10ug
Description: PD-L1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 32-40 KDa and the accession number is G7PSE7.
| Schlagworte: | PDCD1L1, PDL1, B7-H1, B7-H, PDL1PDCD1 ligand 1, CD274 antigenMGC142294, PDCD1LG1, Programmed death ligand 1, CD274... |
| MW: | 40 kD |
ab 108,00 €
PD-L1 Protein, Human, Recombinant (aa 19-238, His & Avi),...
Artikelnummer: TGM-TMPK-00182-100ug
Description: B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation...
| Schlagworte: | B7H1, PDL1, PD-L1, PD-L1B7 homolog 1, PDCD1LG1, B7-H, B7-H1, CD274, PDCD1L1 |
| MW: | 28.1 kD |
ab 798,00 €
PD-L1 Protein, Human, Recombinant (hFc)
Artikelnummer: TGM-TMPY-00676-100ug
Description: PD-L1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52 kDa and the accession number is Q9NZQ7-1.
| Schlagworte: | PDCD1LG1, B7-H, PDCD1L1, PDL1, CD274 molecule, B7-H1, B7H1, PD-L1 |
| MW: | 52 kD |
ab 487,00 €
PD-L1 Protein (Primary Amine Labeling), Cynomolgus/Rhesus...
Artikelnummer: TGM-TMPK-00662-100ug
Description: B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation...
| Schlagworte: | PD-L1, PDL1, B7H1, B7-H1, B7-H, PD-L1B7 homolog 1, PDCD1L1, CD274, PDCD1LG1 |
| MW: | 26 kD |
ab 798,00 €