Zu "K06619" wurden 196 Artikel gefunden!
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NEU
BGG463
Artikelnummer: Cay41146-1
BGG463 is a derivative of BBT594, an inhibitor of the fusion protein Bcr-AblT315I.Formal Name: 6-[[6-(acetylamino)-4-pyrimidinyl]oxy]-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-1-naphthalenecarboxamide. CAS Number: 890129-26-7. Synonyms: K03859, NVP-BGG463. Molecular Formula: C30H29F3N6O3....
| Schlagworte: | K03859, NVP-BGG463,... |
| Anwendung: | BBT594 (Bcr-Abl.T315I inhibitor) derivative |
| CAS | 890129-26-7 |
| MW: | 578.6 D |
ab 47,00 €
NEU
Anti-ABL1
Artikelnummer: CSB-PA001140.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-ABL, Anti-p150, Anti-ABL1, Anti-Proto-oncogene c-Abl, Anti-Tyrosine-protein kinase ABL1, Anti-Abelson... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
ab 106,00 €
NEU
Anti-ABL1
Artikelnummer: CSB-PA001141.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-ABL, Anti-p150, Anti-ABL1, Anti-Proto-oncogene c-Abl, Anti-Tyrosine-protein kinase ABL1, Anti-Abelson... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
NEU
Anti-ABL1
Artikelnummer: CSB-PA008499.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-ABL, Anti-p150, Anti-ABL1, Anti-Proto-oncogene c-Abl, Anti-Tyrosine-protein kinase ABL1, Anti-Abelson... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
ab 106,00 €
NEU
Anti-ABL1/ABL2
Artikelnummer: CSB-PA000795.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-ABL, Anti-p150, Anti-ABL1, Anti-Proto-oncogene c-Abl, Anti-Tyrosine-protein kinase ABL1, Anti-Abelson... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 106,00 €
NEU
Anti-ABL1
Artikelnummer: CSB-PA04355A0Rb.100
Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: ABL1. Antigen Species: Human
| Schlagworte: | Anti-ABL, Anti-p150, Anti-ABL1, Anti-Proto-oncogene c-Abl, Anti-Tyrosine-protein kinase ABL1, Anti-Abelson... |
| Anwendung: | ELISA, IHC, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 163,00 €
GMB 475
Artikelnummer: Cay40463-10
GMB 475 is a proteolysis-targeting chimera (PROTAC) containing the Bcr-Abl inhibitor GNF-5 (Cay-16254) conjugated to VHL ligand 1 (Cay-21591). It induces degradation of Bcr-Abl with a half-maximal degradation concentration (DC50) value of 340 nM. GMB 475 selectively inhibits the proliferation of K562 chronic myeloid...
| Schlagworte: | (4R)-3-methyl-N-[2-[2-[4-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]phenoxy]ethoxy]acetyl]-L-valyl-4-hydroxy-N-[... |
| Anwendung: | Bcr-Abl degradation driving PROTAC |
| CAS | 2490599-18-1 |
| MW: | 861.9 D |
ab 100,00 €
Dasatinib
Artikelnummer: Cay11498-10
Dasatinib is a potent inhibitor of the non-receptor tyrosine kinases Abl and Src as well as other members of the Src family. It is effective at sub-nanomolar concentrations, inhibiting Src, Abl, and Lck with IC50 values of 0.05, 0.5, and 0.4 nM, respectively. At nanomolar concentrations, dasatinib also blocks the...
| Schlagworte: | BMS 354825, Sprycel,... |
| Anwendung: | Tyrosine kinase inhibitor |
| CAS | 302962-49-8 |
| MW: | 488 D |
ab 43,00 €
Abl Substrate Peptide (trifluoroacetate salt)
Artikelnummer: Cay36969-1
Abl substrate peptide is a peptide substrate for the tyrosine kinase Abl. It is selectively phosphorylated by Abl over c-Src kinase at 20 µM. Abl substrate peptide has been used to quantify Abl kinase activity in vitro.Formal Name:...
| Schlagworte: | L-alpha-glutamyl-L-alanyl-L-isoleucyl-L-tyrosyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanyl-L-alanyl-L-lysyl-L-lysyl-L-lysin... |
| Anwendung: | Tyrosine kinase Abl peptide substrate |
| MW: | 1336.6 D |
ab 104,00 €
Anti-c-Abl
Artikelnummer: ELK-EA355.100
c-Abl protein is distributed in both the nucleus and the cytoplasm of cells. It is implicated in regulating cell proliferation, apoptosis, differentiation, cell adhesion, and stress responses. Protein function: Non-receptor tyrosine-protein kinase that plays a role in many key processes linked to cell growth and...
| Schlagworte: | Anti-ABL, Anti-ABL1, Anti-p150, Anti-Proto-oncogene c-Abl, Anti-Tyrosine-protein kinase ABL1, Anti-Abelson... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
283,00 €
Saracatinib
Artikelnummer: Cay11497-5
Saracatinib is a dual inhibitor of the tyrosine kinases c-Src and Abl (IC50 = 2.7 and 30 nM, respectively). It less effectively inhibits other receptor and non-receptor tyrosine kinases as well as assorted serine/threonine kinases. Saracatinib is orally available and blocks cell motility, migration, adhesion,...
| Schlagworte: | AZD 0530,... |
| Anwendung: | c-Src / Abl inhibitor |
| CAS | 379231-04-6 |
| MW: | 542 D |
ab 42,00 €
Dasatinib, Free Base (Sprycel, BMS-354825, CAS...
Artikelnummer: LC-D-3307_5g
Soluble in DMSO at 200 mg/mL, very poorly soluble in ethanol, very poorly soluble in water, maximum solubility in plain water is estimated to be about 10 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility
| Schlagworte: | BMS 354825, Sprycel,... |
| Anwendung: | Tyrosine kinase inhibitor |
| CAS | 302962-49-8 |
| MW: | 488,01 D |
ab 83,00 €