Zu "K06276" wurden 104 Artikel gefunden!
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Anti-PDPK1
Artikelnummer: ATA-HPA008062.100
Polyclonal Antibody against Human PDPK1, Gene description: 3-phosphoinositide dependent protein kinase 1, Alternative Gene Names: PDK1, Validated applications: ICC, WB, Uniprot ID: O15530, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: Serine/threonine...
| Schlagworte: | Anti-PDK1, Anti-PDPK1, Anti-hPDK1, EC=2.7.11.1, Anti-3-phosphoinositide-dependent protein kinase 1 |
| Anwendung: | WB, ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
450,00 €
BX-320
Artikelnummer: TGM-T37561-100mg
Description: BX-320 is an inhibitor of the serine/threonine kinase 3-phosphoinositide-dependent protein kinase 1 (PDK1, IC50= 30 nM).1It is selective for PDK1 over a panel of 10 additional kinases (IC50s = >820 nM for all). BX-320 inhibits Akt and p70S6K1 phosphorylation in PC3 cells (IC50s = 1-3 µM). It induces...
| Anwendung: | PDPK1 inhibitor |
| CAS | 702676-93-5 |
| MW: | 547.45 D |
ab 1.971,00 €
BX517
Artikelnummer: TGM-T4046-100mg
Description: BX517 (PDK1 inhibitor 2) is a potent and selective inhibitor of PDK1. Target: PDK, Akt. Smiles: C\C(=C1\C(=O)Nc2ccc(NC(N)=O)cc12)c1ccc[nH]1. References: Islam I, et al. Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 2: optimization of BX-517. Bioorg Med Chem Lett. 2007 Jul...
| Schlagworte: | PDK1 inhibitor 2, BX-517, BX 517 |
| Anwendung: | PDK1 inhibitor |
| CAS | 850717-64-5 |
| MW: | 282.3 D |
ab 31,00 €
BX795
Artikelnummer: TGM-T1830-100mg
Description: BX795 is an effective and selective PDK1 inhibitor (IC50: 6 nM), and its selectivity is 140- and 1600-fold for PDK1 over PKA and PKC in cell-free assays, respectively. Meanwhile, the selectivity for PDK1 is 100-fold than GSK3beta. Target: IkappaB/IKK, Chk, CDK, Autophagy, c-Kit, PDK. Smiles:...
| Anwendung: | PDKP1 inhibitor |
| CAS | 702675-74-9 |
| MW: | 591.47 D |
ab 55,00 €
BX-912
Artikelnummer: TGM-T1837-100mg
Description: BX-912 is a specific inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1, IC50: 12 nM). The selectivity of BX-912 is more 10 fold than C-Kit, EGFR, PKA, PKC etc. Target: VEGFR, PKA, PDK, Apoptosis, Chk, CDK. Smiles: Brc1cnc(Nc2cccc(NC(=O)N3CCCC3)c2)nc1NCCc1cnc[nH]1. References: Feldman RI, et...
| Anwendung: | PDK1 inhibitor |
| CAS | 702674-56-4 |
| MW: | 471.35 D |
ab 48,00 €
Xanthohumol
Artikelnummer: TGM-T3342-5mg
Description: Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-prenylated chalcones. It inhibits COX-1 and COX-2 activity and shows chemopreventive effects. Target: Apoptosis, COX, Acyltransferase, Others, HSV,...
| Anwendung: | PDPK1 inhibitor |
| CAS | 6754-58-1 |
| MW: | 354.4 D |
ab 60,00 €
PS-47
Artikelnummer: Cay41116-100
PS-47 is an inactive derivative of the 3-phosphoinositide-dependent protein kinase 1 (PDK1) allosteric activator PS-48 that has been used as a negative control for the kinase activity of PDK1.Formal Name: 5-(4-chlorophenyl)-3-phenyl-2E-pentenoic acid. CAS Number: 1180676-33-8. Molecular Formula: C17H15ClO2. Formula...
| Schlagworte: | 5-(4-chlorophenyl)-3-phenyl-2E-pentenoic acid |
| Anwendung: | Inactive PS-48 derivative, PDK1 assay negative control |
| CAS | 1180676-33-8 |
| MW: | 286.8 D |
ab 144,00 €
PS210
Artikelnummer: TGM-T16670-100mg
Description: PS210 is a potent and selective activator of PDK1 (Kd: 3 µM), specifically targeting the PIF-binding pocket of PDK1 without affecting other protein kinases such as S6K, PKB/Akt, or GSK3. Its prodrug, PS423, serves as a substrate-selective inhibitor of PDK1 in cells, inhibiting the phosphorylation and...
| Anwendung: | PDK1 activator |
| CAS | 1221962-86-2 |
| MW: | 380.31 D |
ab 31,00 €
RS1-PDK1 inhibitor
Artikelnummer: TGM-T24741-100mg
Description: RS1-PDK1 inhibitor (RS 1) is a selective inhibitor of the protein kinase PDK1 that can be used to treat and prevent disease or disorders. Target: PDK. Smiles: S(NC1=NC=2C(S1)=CC(Cl)=CC2)(=O)(=O)C=3C=4C(SC3)=CC=CC4. References: Wu Junjun, et al. Selective inhibitors of tumor progression loci-2 (Tpl2)...
| Schlagworte: | RS1, RS 1, RS-1 |
| Anwendung: | PDPK1 (3-phosphoinositide dependent protein kinase-1) inhibitor |
| CAS | 1643958-85-3 |
| MW: | 380.89 D |
ab 287,00 €
PS 48
Artikelnummer: TGM-T3163-100mg
Description: PS 48 has been shown to be a PKB Kinase (PDK1) activator (Kd: 10.3 µM). This compound selectively binds to the PIF-binding pocket of PKB Kinase (PDK1). Target: PDK. Smiles: C(\CCC1=CC=C(Cl)C=C1)(=C/C(O)=O)/C2=CC=CC=C2. References: Han F, et al. Triptolide Suppresses Glomerular Mesangial Cell...
| Anwendung: | phosphopeptide mimetic, PDK1 phosphorylation trigger |
| CAS | 1180676-32-7 |
| MW: | 286.75 D |
ab 46,00 €
Anti-PDPK1
Artikelnummer: CSB-PA003730.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-PDK1, Anti-PDPK1, Anti-hPDK1, EC=2.7.11.1, Anti-3-phosphoinositide-dependent protein kinase 1, 3 phosphoinositide... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-PDPK1 (Ab-241)
Artikelnummer: CSB-PA088763.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
| Schlagworte: | Anti-PDK1, Anti-PDPK1, Anti-hPDK1, EC=2.7.11.1, Anti-3-phosphoinositide-dependent protein kinase 1, 3 phosphoinositide... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
283,00 €