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PS-47
PS-47

Artikelnummer: Cay41116-100

PS-47 is an inactive derivative of the 3-phosphoinositide-dependent protein kinase 1 (PDK1) allosteric activator PS-48 that has been used as a negative control for the kinase activity of PDK1.Formal Name: 5-(4-chlorophenyl)-3-phenyl-2E-pentenoic acid. CAS Number: 1180676-33-8. Molecular Formula: C17H15ClO2. Formula...
Schlagworte: 5-(4-chlorophenyl)-3-phenyl-2E-pentenoic acid
Anwendung: Inactive PS-48 derivative, PDK1 assay negative control
CAS 1180676-33-8
MW: 286.8 D
ab 141,00 €
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Anti-PDPK1
Anti-PDPK1

Artikelnummer: CSB-PA003730.100

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: Anti-PDK1, Anti-PDPK1, Anti-hPDK1, EC=2.7.11.1, Anti-3-phosphoinositide-dependent protein kinase 1, 3 phosphoinositide...
Anwendung: ELISA, WB, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 106,00 €
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Anti-PDPK1 (Ab-241)
Anti-PDPK1 (Ab-241)

Artikelnummer: CSB-PA088763.100

Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
Schlagworte: Anti-PDK1, Anti-PDPK1, Anti-hPDK1, EC=2.7.11.1, Anti-3-phosphoinositide-dependent protein kinase 1, 3 phosphoinositide...
Anwendung: ELISA, WB, IHC, IF
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
275,00 €
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Anti-Phospho-PDPK1 (Tyr9)
Anti-Phospho-PDPK1 (Tyr9)

Artikelnummer: CSB-PA781374.100

Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits with...
Schlagworte: Anti-phospho-PDK1, Anti-phospho-PDPK1, Anti-phospho-hPDK1, EC=2.7.11.1, Anti-phospho-3-phosphoinositide-dependent protein...
Anwendung: ELISA, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
330,00 €
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NEU
Anti-Phospho-PDPK1 (Ser241)
Anti-Phospho-PDPK1 (Ser241)

Artikelnummer: CSB-PA910286.100

Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
Schlagworte: Anti-phospho-PDK1, Anti-phospho-PDPK1, Anti-phospho-hPDK1, EC=2.7.11.1, Anti-phospho-3-phosphoinositide-dependent protein...
Anwendung: ELISA, WB, IHC, IF
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
330,00 €
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Mouse PDPK1 (Phosphoinositide Dependent Protein Kinase 1) ELISA Kit
Mouse PDPK1 (Phosphoinositide Dependent Protein Kinase 1)...

Artikelnummer: ELK-ELK6179.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PDPK1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PDPK1. Next,...
Schlagworte: Pdk1, mPDK1, Pdpk1, EC=2.7.11.1, 3-phosphoinositide-dependent protein kinase 1
Anwendung: ELISA
Spezies-Reaktivität: mouse
ab 365,00 €
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GSK2334470
GSK2334470

Artikelnummer: Cay18095-5

3-Phosphoinositide-dependent protein kinase 1 (PDK1) is a serine-threonine kinase that plays an important role in growth factor signaling by phosphorylating and activating a group of kinases, including protein kinase (PK)B, PKA, and certain isoforms of PKC. GSK2334470 is an inhibitor of PDK1 (IC50 = ~10 nM) that...
Schlagworte: (3S,6R)-1-[6-(3-amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-3-piperidinecarboxamide
Anwendung: PDPK1 inhibitor
CAS 1227911-45-6
MW: 462.6 D
ab 102,00 €
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6BIO
6BIO

Artikelnummer: AG-CR1-0056-M001

Phosphoinositide-dependent kinase 1 (PDK1) inhibitor, Potent, reversible and ATP-competitive glycogen synthase kinase-3alpha/beta (GSK-3alpha/beta) inhibitor, JAK/STAT3 signaling inhibitor, Apoptosis inducer, Potent antiproliferative agent in malignant lymphoid cell.
Schlagworte: 2’Z,3’E)-6-Bromoindirubin-3’-oxime
Anwendung: PDPK1 inhibitor
CAS 667463-62-9
MW: 356,2 D
ab 39,00 €
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Xanthohumol
Xanthohumol

Artikelnummer: Cay15399-10

Xanthohumol is a natural prenylated chalcone isolated from the hop plant, H. lupulus. Xanthohumol and its metabolites induce protective detoxification enzymes, at least in part via the nuclear factor erythroid-2-related factor 2 pathway. It inhibits phosphoinositide-dependent kinase 1 (IC50 = 6.6 µM) but not PKC in...
Schlagworte: (2E)-1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one
Anwendung: PDPK1 inhibitor
CAS 6754-58-1
MW: 354.4 D
ab 32,00 €
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BX-795
BX-795

Artikelnummer: Cay14932-5

BX-795 is a multi-kinase inhibitor that is an ATP-competitive inhibitor of 3-phosphoinositide-dependent protein kinase 1 (PDK1) and TANK-binding kinase 1 (TBK1, IC50s = 6 and 11 nM, respectively). It also inhibits the CAMK family kinases AMPK-related kinase 5 (NUAK1, IC50 = 5 nM) and microtubule affinity-regulating...
Schlagworte: N-[3-[[5-iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide
Anwendung: PDPK1 inhibitor
CAS 702675-74-9
MW: 591.5 D
ab 109,00 €
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GSK2334470
GSK2334470

Artikelnummer: LKT-G7344.5

GSK2334470 is a potent 3-phosphoinositide-dependent protein kinase (PDK1) inhibitor (IC50 ~ 10 nM).
Schlagworte: GSK-2334470,...
Anwendung: PDPK1 inhibitor
CAS 1227911-45-6
MW: 462.59 D
ab 90,00 €
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BX-912
BX-912

Artikelnummer: Cay14708-1

3-Phosphoinositide-dependent protein kinase 1 (PDK1) is a serine-threonine kinase that phosphorylates and activates a range of other kinases, including protein kinase (PK)B, PKA, and certain isoforms of PKC. BX-912 is a potent, ATP-competitive inhibitor of PDK1 (IC50 = 26 nM). It less effectively inhibits a panel of...
Schlagworte: N-[3-[[5-bromo-4-[[2-(1H-imidazol-5-yl)ethyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide
Anwendung: PDK1 inhibitor
CAS 702674-56-4
MW: 471.4 D
ab 61,00 €
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