Zu "K06128" wurden 34 Artikel gefunden!
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ML348
Artikelnummer: TGM-T3439-100mg
Description: ML348 (GNF-Pf-1127) is a selective, reversible inhibitor of lysophospholipase 1 (LYPLA1) with an IC50 of 210 nM. Target: Phospholipase, Others. Smiles: FC(F)(F)c1ccc(Cl)c(NC(=O)CN2CCN(CC2)C(=O)c2ccco2)c1. References: Adibekian A, et al. National Center for Biotechnology Information (US), 2010-.2013 Apr...
| Schlagworte: | GNF-Pf-1127 |
| Anwendung: | Reversible LYPLA1 inhibitor |
| CAS | 899713-86-1 |
| MW: | 415.79 D |
ab 40,00 €
ML-211
Artikelnummer: TGM-T8974-100mg
Description: ML-211 is a carbamate-based dual inhibitor of LYPLA1 (IC50 = 17 nM) and LYPLA2 (IC50 = 30 nM). Target: Others. Smiles: C(O)(C1=NN(C(=O)N2CCC(C(C)(C)C)CC2)N=C1)(C3=CC=CC=C3)C4=CC=CC=C4. References: Adibekian A , Martin B R , Chang J W , et al. Characterization of a Selective, Reversible Inhibitor of...
| Anwendung: | LYPLA1 / LYPLA2 inhibitor |
| CAS | 2205032-89-7 |
| MW: | 418.53 D |
ab 122,00 €
APT-1 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPJ-00702-10ug
Description: Acyl-Protein Thioesterase 1 (APT-1) is lysophospholipase that belongs to the AB hydrolase 2 family. Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. APT-1 performs on biological membranes to regulate the multifunctional lysophospholipids....
| Schlagworte: | LPL1, LPL-I, APT-1, Acyl-Protein Thioesterase 1, Lysophospholipase 1, LYPLA1, hAPT1, Lysophospholipase I, LysoPLA I, APT1 |
| MW: | 25 kD |
ab 128,00 €
Acyl-protein thioesterase 1 (Lypla1), mouse, recombinant
Artikelnummer: CSB-EP013268MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 1-230aa. Protein Length: Full Length. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MCGNNMSAPM PAVVPAARKA TAAVIFLHGL GDTGHGWAEA FAGIKSPHIK YICPHAPVMP VTLNMNMAMP SWFDIVGLSP DSQEDESGIK QAAETVKALI DQEVKNGIPS NRIILGGFSQ GGALSLYTAL TTQQKLAGVT...
| Schlagworte: | Apt1, APT-1, LPL-I, Lypla1, LysoPLA I, EC=3.1.2.-, Lysophospholipase I, Lysophospholipase 1, Acyl-protein thioesterase 1,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 51.7 kD |
ab 292,00 €
Anti-LYPLA1
Artikelnummer: CSB-PA003181.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-APT1, Anti-APT-1, Anti-LPL-I, Anti-hAPT1, Anti-LYPLA1, Anti-LysoPLA I, EC=3.1.2.-, Anti-Lysophospholipase I,... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-LYPLA1
Artikelnummer: CSB-PA076865.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-APT1, Anti-APT-1, Anti-LPL-I, Anti-hAPT1, Anti-LYPLA1, Anti-LysoPLA I, EC=3.1.2.-, Anti-Lysophospholipase I,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
283,00 €
ML-211
Artikelnummer: Cay17630-1
Lysophospholipase 1 (LYPLA1) is a protein palmitoyl thioesterase responsible for depalmitoylation of the oncogene HRas. Palmitoylation of such oncogenes is thought to be required for trafficking and malignant transformation, making LYPLA1 a target for downregulating oncogenic signaling. ML-211 is a carbamate-based...
| Schlagworte: | [4-(1,1-dimethylethyl)-1-piperidinyl][4-(hydroxydiphenylmethyl)-2H-1,2,3-triazol-2-yl]-methanone |
| Anwendung: | LYPLA1 / LYPLA2 inhibitor |
| CAS | 2205032-89-7 |
| MW: | 418.5 D |
ab 52,00 €
ML-348
Artikelnummer: Cay18523-1
Lysophospholipase 1 (LYPLA1) is a protein palmitoyl thioesterase responsible for depalmitoylation of the oncogene HRas. Palmitoylation of such oncogenes is thought to be required for trafficking and malignant transformation, making LYPLA1 a target for downregulating oncogenic signaling. ML-348 is a reversible LYPLA1...
| Schlagworte: | CID 3238952, SID 160654487, N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(2-furanylcarbonyl)-1-piperazineacetamide |
| Anwendung: | Reversible LYPLA1 inhibitor |
| CAS | 899713-86-1 |
| MW: | 415.8 D |
ab 44,00 €
Anti-LYPLA1
Artikelnummer: ATA-HPA050941.100
Protein function: Acts as a acyl-protein thioesterase (PubMed:19439193, PubMed:20418879). Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS (PubMed:20418879). Has depalmitoylating activity toward KCNMA1 (PubMed:22399288). Could also depalmitoylate ADRB2...
| Schlagworte: | Anti-APT1, Anti-APT-1, Anti-LPL-I, Anti-hAPT1, Anti-LYPLA1, Anti-LysoPLA I, EC=3.1.2.-, Anti-Lysophospholipase I,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 358,00 €
LYPLA1 (human), recombinant protein
Artikelnummer: ABS-PP-3859.20
| Schlagworte: | Acyl-protein thioesterase 1, APT-1, hAPT1, Lysophospholipase 1, Lysophospholipase I, LPL-I, LysoPLA I, Palmitoyl-protein... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 25.5 kD |
ab 90,00 €
Anti-Lypla1
Artikelnummer: CSB-PA013268DA01MO.100
Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: Lypla1. Antigen Species: Mouse
| Schlagworte: | Anti-Apt1, Anti-APT-1, Anti-LPL-I, Anti-Lypla1, Anti-LysoPLA I, EC=3.1.2.-, Anti-Lysophospholipase I,... |
| Anwendung: | ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
ab 167,00 €
Anti-Lypla1, HRP conjugated
Artikelnummer: CSB-PA013268DB01MO.100
Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: Lypla1. Antigen Species: Mouse
| Schlagworte: | Anti-Apt1, Anti-APT-1, Anti-LPL-I, Anti-Lypla1, Anti-LysoPLA I, EC=3.1.2.-, Anti-Lysophospholipase I,... |
| Anwendung: | ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
ab 167,00 €