Zu "K06069" wurden 31 Artikel gefunden!
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PKC-iota inhibitor 1
Artikelnummer: TGM-T8764-100mg
Description: PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-iota , IC50 : 0.34 µM). Target: PKC. Smiles: Nc1ncc(cc1C(=O)Nc1ccncc1)-c1cccc(c1)N1CCNCC1. References: Kwiatkowski J, et al. Fragment-based Discovery of a Small-Molecule Protein Kinase C-iota Inhibitor Binding Post-kinase Domain...
| Anwendung: | PKC-iota inhibitor |
| CAS | 2328094-11-5 |
| MW: | 374.44 D |
ab 114,00 €
PKC iota Protein, Human, Recombinant (GST)
Artikelnummer: TGM-TMPY-04455-50ug
Description: Protein kinase C iota type, also known as Atypical protein kinase C-lambda/iota, aPKC-lambda/iota and PRKCI, is a cytoplasm, membrane and nucleus protein which belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family and PKC subfamily. PRKCI contains one AGC-kinase C-terminal domain,...
| Schlagworte: | PKC iota, PKCI, nPKC-iota, protein kinase C, iota, nPKC-iota, DXS1179E, protein kinase C, iota |
| MW: | 93.5 kD |
397,00 €
PKC iota/lambda, active human recombinant protein
Artikelnummer: BPS-40015
Active human PKC lambda (GenBank Accession No. NM_002740), (a.a. 2- 587) with N-terminal GST tag, expressed in a Baculovirus infected Sf9 cell expression system. MW= 93 kDa.
| Schlagworte: | PRKCI, DXS1179E, nPKC-iota, EC=2.7.11.13, PRKC-lambda/iota, aPKC-lambda/iota, Protein kinase C iota type, Atypical protein... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 93 kD |
536,00 €
Anti-PKC iota
Artikelnummer: ARG55525.100
Protein function: Calcium- and diacylglycerol-independent serine/ threonine-protein kinase that plays a general protective role against apoptotic stimuli, is involved in NF-kappa-B activation, cell survival, differentiation and polarity, and contributes to the regulation of microtubule dynamics in the early...
| Schlagworte: | Anti-PRKCI, Anti-DXS1179E, Anti-nPKC-iota, EC=2.7.11.13, Anti-PRKC-lambda/iota, Anti-aPKC-lambda/iota, Anti-Protein kinase... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
616,00 €
Anti-PKC iota
Artikelnummer: NSJ-R31734
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Protein kinase C iota, also called PKCI, is an enzyme that in humans is encoded by the PRKCI gene. This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. This protein kinase is calcium-independent and...
| Schlagworte: | Anti-PRKCI, Anti-DXS1179E, Anti-nPKC-iota, EC=2.7.11.13, Anti-aPKC-lambda/iota, Anti-PRKC-lambda/iota, Anti-Protein kinase... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
772,00 €
Ingenol
Artikelnummer: Cay14031-5
Ingenol is a diterpenoid related to phorbol, derived from the milkweed plant E. peplus. It is a protein kinase C activator that displays a Ki value of 30 µM and an ED50 value of 27 µM in vitro. Most ingenol esters are tumor-promoting. However, ingenol mebutate possesses anti-tumor activity when used topically for...
| Schlagworte: | (1aR,2S,5R,5aR,6S,8aS,9R,10aR)-1a,2,5,5a,6,9,10,10a-octahydro-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-1H-2... |
| Anwendung: | PKC activator |
| CAS | 30220-46-3 |
| MW: | 348.4 D |
ab 47,00 €
CRT0066854
Artikelnummer: Cay28463-10
CRT0066854 is an inhibitor of PKCiota and PKCzeta (IC50s = 132 and 639 nM, respectively). It also inhibits the Rho-associated kinase II (ROCK2) kinase domain (IC50 = 620 nM). It is selective for these atypical PKCs and ROCK2 over typical PKCs and 98 other kinases in a panel at 1 µM. CRT0066854 decreases...
| Schlagworte: | (2S)-3-phenyl-N1-[5,6,7,8-tetrahydro-2-(4-pyridinyl)[1]benzothieno[2,3-d]pyrimidin-4-yl]-1,2-propanediamine |
| Anwendung: | PKCiota / PKCzeta inhibitor |
| CAS | 1438881-19-6 |
| MW: | 415.6 D |
ab 67,00 €
Anti-PRKCI
Artikelnummer: ATA-HPA026574.100
Protein function: Calcium- and diacylglycerol-independent serine/ threonine- protein kinase that plays a general protective role against apoptotic stimuli, is involved in NF-kappa-B activation, cell survival, differentiation and polarity, and contributes to the regulation of microtubule dynamics in the early...
| Schlagworte: | Anti-PRKCI, Anti-DXS1179E, Anti-nPKC-iota, EC=2.7.11.13, Anti-PRKC-lambda/iota, Anti-aPKC-lambda/iota, Anti-Protein kinase... |
| Anwendung: | WB, IHC, ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 320,00 €
Anti-PRKCI
Artikelnummer: ATA-HPA038635.100
Protein function: Calcium- and diacylglycerol-independent serine/ threonine- protein kinase that plays a general protective role against apoptotic stimuli, is involved in NF-kappa-B activation, cell survival, differentiation and polarity, and contributes to the regulation of microtubule dynamics in the early...
| Schlagworte: | Anti-PRKCI, Anti-DXS1179E, Anti-nPKC-iota, EC=2.7.11.13, Anti-PRKC-lambda/iota, Anti-aPKC-lambda/iota, Anti-Protein kinase... |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 320,00 €
Anti-PKC iota / PRKCI, clone PRKCI/4911
Artikelnummer: NSJ-V9171-100UG
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as...
| Schlagworte: | Anti-PRKCI, Anti-DXS1179E, Anti-nPKC-iota, EC=2.7.11.13, Anti-PRKC-lambda/iota, Anti-aPKC-lambda/iota, Anti-Protein kinase... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-PKC iota / PRKCI, clone PRKCI/4911
Artikelnummer: NSJ-V9171SAF-100UG
1 mg/ml in 1X PBS, BSA free, sodium azide free. Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein...
| Schlagworte: | Anti-PRKCI, Anti-DXS1179E, Anti-nPKC-iota, EC=2.7.11.13, Anti-PRKC-lambda/iota, Anti-aPKC-lambda/iota, Anti-Protein kinase... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
781,00 €
NEU
Anti-aPKC
Artikelnummer: CSB-PA180943XA01DLU.2
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-CG30475, EC=2.7.11.13, Anti-Atypical protein kinase C, aPKC Antibody |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Drosophila melanogaster (Fruit fly) |
ab 1.529,00 €