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Zu "K06062" wurden 56 Artikel gefunden!
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Artikelnummer: Cay10782-100
Gcn5 and PCAF are highly homologous members of the Gcn5-related N-acetyltransferase (GNAT) superfamily of N-acetyltransferases involved in histone acetylation. Gcn5 and PCAF contain a highly conserved central core with divergent N- and C-terminal ends. Gcn5/PCAF are enzymatic subunits that exist in a mutually...
Schlagworte: | hGCN5, hGCN5, STAF97, STAF97, Lysine acetyltransferase 2A, Lysine acetyltransferase 2A, Histone acetyltransferase GCN5,... |
Anwendung: | Enzyme activity |
MW: | 96,3 kD |
579,00 €
Artikelnummer: CSB-PA002657.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-hGCN5, Anti-STAF97, Anti-Lysine acetyltransferase 2A, Anti-Histone acetyltransferase GCN5, Anti-Histone... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 106,00 €
Artikelnummer: CSB-PA003718.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-P/CAF, Anti-Histone acetylase PCAF, Anti-P300/CBP-associated factor, Anti-Lysine acetyltransferase 2B, Anti-Histone... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
Artikelnummer: CSB-PA005734.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-P/CAF, Anti-Histone acetylase PCAF, Anti-P300/CBP-associated factor, Anti-Lysine acetyltransferase 2B, Anti-Histone... |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
106,00 €
Artikelnummer: CSB-PA000141.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-acetyl-P/CAF, Anti-acetyl-Histone acetylase PCAF, Anti-acetyl-P300/CBP-associated factor, Anti-acetyl-Lysine... |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 106,00 €
Artikelnummer: Cay10566-5
Garcinol is a polyisoprenylated benzophenone that has been found in G. indica and has diverse biological activities. It inhibits the histone acetyltransferases (HATs) p300 and p300/CREB-binding protein-associated factor (PCAF, IC50s = ~7 and ~5 µM, respectively), as well as COX-1, microsomal prostaglandin E2 (PGE2)...
Schlagworte: | Camboginol,... |
Anwendung: | HATs inhibitor |
CAS | 78824-30-3 |
MW: | 602.8 D |
ab 77,00 €
Artikelnummer: Cay10974-1
CAY10669 is an inhibitor of the histone acetyltransferase PCAF (p300/CREB-binding protein-associated factor, IC50 = 662 µM), displaying a 2-fold improvement in inhibitory potency over anacardic acid (Cay-13144). At 30-60 µM, CAY10669 can dose-dependently inhibit histone H4 acetylation in HepG2 cells in vitro.Formal...
Schlagworte: | 2-hydroxy-6-[(1Z)-2-[4-(pentyloxy)phenyl]ethenyl]-benzoic acid |
Anwendung: | Histone acetyltransferase pCAF inhibitor |
CAS | 1243583-88-1 |
MW: | 326.4 D |
ab 109,00 €
Artikelnummer: Cay12086-5
Gcn5 is a chromatin modifying factor whose HAT activity is required to acetylate histone H3 lysine 9 (K9) and K14, which facilitates transcription elongation by relaxing nucleosomes. CPTH2 inhibits the HAT activity of Gcn5 both in vitro and in vivo, reducing histone H3K14 acetylation at a concentration of 0.8 mM. It...
Schlagworte: | 2-[4-(4-chlorophenyl)-2-thiazolyl]hydrazone-cyclopentanone, monohydrochloride |
Anwendung: | HAT inhibitor |
CAS | 2108899-91-6 |
MW: | 328.3 D |
ab 130,00 €
Artikelnummer: Cay12095-1
Gcn5 is a chromatin modifying factor whose HAT activity is required to acetylate histone H3 lysine 9 (K9) and K14, which facilitates transcription elongation by relaxing nucleosomes. Butyrolactone 3 specifically inhibits the histone acetyltransferase Gcn5 with an IC50 value of 100 µM and has an affinity to the Gcn5...
Schlagworte: | rel-tetrahydro-4-methylene-5-oxo-2R-propyl-3S-furancarboxylic acid |
Anwendung: | HAT inhibitor |
CAS | 778649-18-6 |
MW: | 184.2 D |
ab 73,00 €
Artikelnummer: BPS-50079L
The GCN5 Chemiluminescent Assay Kit is an enzyme-linked immunosorbent assay (ELISA) designed to screen for inhibitors of GCN5. The GCN5 Chemiluminescent Assay Kit is based on the GCN5 enzyme transferring an acetyl group from an acetyl donor (acetyl CoA) to a histone substrate. The acetylated histone is recognized by...
Schlagworte: | hGCN5, STAF97, Lysine acetyltransferase 2A, Histone acetyltransferase GCN5, Histone acetyltransferase KAT2A, Histone... |
Anwendung: | Studying enzyme activity, drug discovery, HTS |
Spezies-Reaktivität: | human |
686,00 €
Artikelnummer: Cay13144-10
Anacardic acid, isolated from cashew shells or several other medicinal plants, is the general name given to a family of four different 6-alkyl salicyclic acids having varying degrees of unsaturation in the 15-carbon alkyl chain. These compounds are associated with anti-inflammatory, anti-tumor, molluscicidal, and...
Schlagworte: | 6-pentadecyl Salicylic Acid, 2-hydroxy-6-pentadecyl-benzoic acid |
Anwendung: | HAT inhibitor |
CAS | 16611-84-0 |
MW: | 348.5 D |
ab 35,00 €
Artikelnummer: Cay23421-10
GSK4027 is a p300/CBP-associated factor (PCAF)/general control nonderepressible 5 (GCN5) bromodomain inhibitor (Ki = 1.4 nM, IC50 = 60 nM in a chromatin engagement assay). It is greater than 18,000-fold selective for PCAF and GCN5 over BET family bromodomains and greater than 70-fold selective over other bromodomain...
Schlagworte: | 4-bromo-2-methyl-5-[[(3R,5R)-1-methyl-5-phenyl-3-piperidinyl]amino]-3(2H)-pyridazinone |
Anwendung: | PCAF / GCN5 bromodomain inhibitor |
CAS | 2079896-25-4 |
MW: | 377.3 D |
ab 60,00 €