Zu "K06062" wurden 68 Artikel gefunden!
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Gcn5 (human, recombinant)
Artikelnummer: Cay10782-100
Gcn5 and PCAF are highly homologous members of the Gcn5-related N-acetyltransferase (GNAT) superfamily of N-acetyltransferases involved in histone acetylation. Gcn5 and PCAF contain a highly conserved central core with divergent N- and C-terminal ends. Gcn5/PCAF are enzymatic subunits that exist in a mutually...
| Schlagworte: | hGCN5, hGCN5, STAF97, STAF97, Lysine acetyltransferase 2A, Lysine acetyltransferase 2A, Histone acetyltransferase GCN5,... |
| Anwendung: | Enzyme activity |
| MW: | 96,3 kD |
590,00 €
Butyrolactone 3
Artikelnummer: TGM-T14839-1mg
Description: Butyrolactone 3 (MB-3) is a histone acetyltransferase Gcn5 inhibitor with a weak affinity for CBP.Butyrolactone 3 has antimicrobial activity and has been used in cancer, metabolic and neurological disorders. Target: Epigenetic Reader Domain, Antibacterial. Smiles: CCC[C@H]1OC(=O)C(=C)[C@@H]1C(O)=O....
| Schlagworte: | MB-3, MB3, MB 3 |
| Anwendung: | HAT inhibitor |
| CAS | 778649-18-6 |
| MW: | 184.19 D |
198,00 €
CAY10669
Artikelnummer: TGM-T35818-10mg
Description: CAY10669 is an inhibitor of the histone acetyltransferase PCAF (p300/CREB-binding protein-associated factor, IC50 = 662 µM), displaying a 2-fold improvement in inhibitory potency over anacardic acid . At 30-60 µM, CAY10669 can dose-dependently inhibit histone H4 acetylation in HepG2 cells in vitro....
| Anwendung: | Histone acetyltransferase pCAF inhibitor |
| CAS | 1243583-88-1 |
| MW: | 326.39 D |
ab 198,00 €
CAY10685
Artikelnummer: TGM-T35820-10mg
Description: CAY10685 is a cell-active analog of the lysine acetyltransferase inhibitor CPTH2 that contains an alkyne moiety for use in click chemistry reactions. Its ability to inhibit N-acetyltransferase 10 activity has been used to modulate chromatin organization in order to study changes in nuclear architecture...
| Anwendung: | Click chemistry, lysine acetyltransferase inhibitor |
| CAS | 1613116-16-7 |
| MW: | 329.85 D |
ab 77,00 €
Anti-KAT2A
Artikelnummer: CSB-PA002657.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-hGCN5, Anti-STAF97, Anti-Lysine acetyltransferase 2A, Anti-Histone acetyltransferase GCN5, Anti-Histone... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 126,00 €
Anti-KAT2B
Artikelnummer: CSB-PA003718.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-P/CAF, Anti-Histone acetylase PCAF, Anti-P300/CBP-associated factor, Anti-Lysine acetyltransferase 2B, Anti-Histone... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-KAT2B
Artikelnummer: CSB-PA005734.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-P/CAF, Anti-Histone acetylase PCAF, Anti-P300/CBP-associated factor, Anti-Lysine acetyltransferase 2B, Anti-Histone... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
126,00 €
Anti-Acetyl-KAT2B (K428)
Artikelnummer: CSB-PA000141.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-acetyl-P/CAF, Anti-acetyl-Histone acetylase PCAF, Anti-acetyl-P300/CBP-associated factor, Anti-acetyl-Lysine... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 126,00 €
Garcinol
Artikelnummer: Cay10566-5
Garcinol is a polyisoprenylated benzophenone that has been found in G. indica and has diverse biological activities. It inhibits the histone acetyltransferases (HATs) p300 and p300/CREB-binding protein-associated factor (PCAF, IC50s = ~7 and ~5 µM, respectively), as well as COX-1, microsomal prostaglandin E2 (PGE2)...
| Schlagworte: | Camboginol,... |
| Anwendung: | HATs inhibitor |
| CAS | 78824-30-3 |
| MW: | 602.8 D |
ab 78,00 €
CAY10669
Artikelnummer: Cay10974-1
CAY10669 is an inhibitor of the histone acetyltransferase PCAF (p300/CREB-binding protein-associated factor, IC50 = 662 µM), displaying a 2-fold improvement in inhibitory potency over anacardic acid (Cay-13144). At 30-60 µM, CAY10669 can dose-dependently inhibit histone H4 acetylation in HepG2 cells in vitro.Formal...
| Schlagworte: | 2-hydroxy-6-[(1Z)-2-[4-(pentyloxy)phenyl]ethenyl]-benzoic acid |
| Anwendung: | Histone acetyltransferase pCAF inhibitor |
| CAS | 1243583-88-1 |
| MW: | 326.4 D |
ab 111,00 €
CPTH2 (hydrochloride)
Artikelnummer: Cay12086-5
Gcn5 is a chromatin modifying factor whose HAT activity is required to acetylate histone H3 lysine 9 (K9) and K14, which facilitates transcription elongation by relaxing nucleosomes. CPTH2 inhibits the HAT activity of Gcn5 both in vitro and in vivo, reducing histone H3K14 acetylation at a concentration of 0.8 mM. It...
| Schlagworte: | 2-[4-(4-chlorophenyl)-2-thiazolyl]hydrazone-cyclopentanone, monohydrochloride |
| Anwendung: | HAT inhibitor |
| CAS | 2108899-91-6 |
| MW: | 328.3 D |
ab 133,00 €
Butyrolactone 3
Artikelnummer: Cay12095-1
Gcn5 is a chromatin modifying factor whose HAT activity is required to acetylate histone H3 lysine 9 (K9) and K14, which facilitates transcription elongation by relaxing nucleosomes. Butyrolactone 3 specifically inhibits the histone acetyltransferase Gcn5 with an IC50 value of 100 µM and has an affinity to the Gcn5...
| Schlagworte: | rel-tetrahydro-4-methylene-5-oxo-2R-propyl-3S-furancarboxylic acid |
| Anwendung: | HAT inhibitor |
| CAS | 778649-18-6 |
| MW: | 184.2 D |
ab 74,00 €