- Suchergebnis für K05931
Cookie-Einstellungen
Diese Website benutzt Cookies, die für den technischen Betrieb der Website erforderlich sind und stets gesetzt werden. Andere Cookies, die den Komfort bei Benutzung dieser Website erhöhen, der Direktwerbung dienen oder die Interaktion mit anderen Websites und sozialen Netzwerken vereinfachen sollen, werden nur mit Ihrer Zustimmung gesetzt.
Konfiguration
Technisch erforderlich
Diese Cookies sind für die Grundfunktionen des Shops notwendig.
"Alle Cookies ablehnen" Cookie
"Alle Cookies annehmen" Cookie
Ausgewählter Shop
CSRF-Token
Cookie-Einstellungen
FACT-Finder Tracking
Individuelle Preise
Kundenspezifisches Caching
Session
Währungswechsel
Komfortfunktionen
Diese Cookies werden genutzt um das Einkaufserlebnis noch ansprechender zu gestalten, beispielsweise für die Wiedererkennung des Besuchers.
Facebook-Seite in der rechten Blog - Sidebar anzeigen
Merkzettel
Statistik & Tracking
Endgeräteerkennung
Kauf- und Surfverhalten mit Google Tag Manager
Partnerprogramm
Zu "K05931" wurden 47 Artikel gefunden!
Filter schließen
Filtern nach:
Für die Filterung wurden keine Ergebnisse gefunden!
Artikelnummer: ABS-KC-6065.100
Protein function: Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from...
Schlagworte: | Anti-Histone-arginine methyltransferase CARM1, Anti-Coactivator-associated arginine methyltransferase 1, Anti-Protein... |
Wirt: | Mouse |
Spezies-Reaktivität: | human, mouse |
ab 232,00 €
Artikelnummer: TGM-T5605-100mg
Description: EZM 2302 (GSK3359088) is a selective, and orally available arginine methyltransferase CARM1 inhibitor (IC50: 6 nM). Target: Histone Methyltransferase. Smiles: CNC[C@@H](O)COc1ccc(Cl)c(c1)-c1nc(N2CC3(C2)CCN(CC3)C(=O)OC)c(C)c(n1)-c1c(C)noc1C. References: Drew AE, et al. Identification of a CARM1 Inhibitor...
Schlagworte: | GSK3359088 |
Anwendung: | PRMT4 inhibitor |
CAS | 1628830-21-6 |
MW: | 585.09 D |
ab 67,00 €
Artikelnummer: CSB-PA447549.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
Schlagworte: | Anti-phospho-PRMT4, Anti-phospho-CARM1, Anti-phospho-Protein arginine N-methyltransferase 4, Anti-phospho-Histone-arginine... |
Anwendung: | ELISA, WB, IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
340,00 €
Artikelnummer: A300-421A
Protein function: Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from...
Schlagworte: | Anti-CARM1, Anti-PRMT4, Anti-Protein arginine N-methyltransferase 4, Anti-Histone-arginine methyltransferase CARM1,... |
Anwendung: | WB, IP, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 178,00 €
Artikelnummer: BPS-51047
Active human PRMT4 (CARM1) (GenBank Accession No. NM_199141), amino-acids 2-end, with N-terminal HIS tag, MW=66 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Schlagworte: | CARM1, PRMT4, Protein arginine N-methyltransferase 4, Histone-arginine methyltransferase CARM1, Coactivator-associated... |
Anwendung: | Enzyme kinetics, inhibitor screening |
MW: | 66 kD |
678,00 €
Artikelnummer: Cay10569-100
Ellagic acid is a polyphenolic antioxidant that is abundant in many fruits, vegetables, plant bark, and peels. It has anti-carcinogenic, anti-mutagenic, anti-inflammatory, and organ-preserving properties, presumably related to its ability to alter cytochrome P450 activity and improve metabolism and clearance of...
Schlagworte: | Gallogen, Lagistase, TBBD, 2,3,7,8-tetrahydroxy-[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione |
Anwendung: | Antioxidant |
CAS | 476-66-4 |
MW: | 302.2 D |
ab 27,00 €
Artikelnummer: Cay29954-1
EZM2302 is an inhibitor of protein arginine methyltransferase 4 (PRMT4, IC50 = 6 nM). It decreases asymmetric methylation of the PRMT4 substrate PABP1 (IC50 = 0.038 µM) and increases levels of demethylated SmB (EC50 = 0.018 µM) in RPMI-8226 multiple myeloma cells. EZM2302 inhibits proliferation in a panel of 36...
Schlagworte: | GSK3359088,... |
Anwendung: | PRMT4 inhibitor |
CAS | 1628830-21-6 |
MW: | 585.1 D |
ab 94,00 €
Artikelnummer: ARG53996.100
Protein function: Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from...
Schlagworte: | Anti-CARM1, Anti-PRMT4, EC=2.1.1.-, EC=2.1.1.125, Anti-Protein arginine N-methyltransferase 4, Anti-Histone-arginine... |
Anwendung: | WB, IP |
Wirt: | Mouse |
Spezies-Reaktivität: | human, mouse |
658,00 €
Artikelnummer: Cay18361-5
MS023 is an inhibitor of type I protein arginine methyltransferases (PRMTs, IC50s = 30, 119, 83, 4, and 5 nM for PRMT1, -3, -4, -6, and -8, respectively). It is selective for these type I PRMTs over PRMT5, -7, and -9, as well as a panel of 25 protein lysine methyltransferases (PKMTs) and DNA methyltransferases...
Schlagworte: | N1-methyl-N1-[[4-[4-(1-methylethoxy)phenyl]-1H-pyrrol-3-yl]methyl]-1,2-ethanediamine, trihydrochloride |
Anwendung: | Potent, selective type I PRMT inhibitor |
CAS | 2108631-19-0 |
MW: | 396.8 D |
ab 78,00 €
Artikelnummer: IHC-00045
Protein function: Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from...
Schlagworte: | Anti-CARM1, Anti-PRMT4, Anti-Protein arginine N-methyltransferase 4, Anti-Histone-arginine methyltransferase CARM1,... |
Anwendung: | IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 178,00 €
Artikelnummer: Cay11033-1
PRMT4/CARM1 Inhibitor selectively blocks the activity of PRMT4/CARM1 with an IC50 value of 7.1 µM. It displays very low affinity towards PRMT1 and SET7 with IC50 values of 63 and 943 µM, respectively. In human prostate cancer LNCaP cells, this compound reduced the prostate-specific antigen promoter activity at 8-10...
Schlagworte: | Protein Arginine Methyltransferase 4/Coactivator-Associated Arginine Methyltransferase 1 Inhibitor,... |
CAS | 1020399-49-8 |
MW: | 555.3 D |
ab 111,00 €
Artikelnummer: Cay18348-25
MS049 is a potent and selective inhibitor of PRMT4 (IC50 = 34 nM) and PRMT6 (IC50 = 43 nM). It is less active against additional type I PRMTs (IC50s = >130, >220, and 1.6 µM for PRMT1, PRMT3, and PRMT8, respectively) and displays no inhibition against type II or type III PRMTs nor any additional methyltransferases...
Schlagworte: | N-methyl-4-(phenylmethoxy)-1-piperidineethanamine, dihydrochloride |
Anwendung: | PRMT4 inhibitor, PRMT6 inhibitor |
CAS | 2095432-59-8 |
MW: | 321.3 D |
ab 61,00 €