Zu "K05917" wurden 93 Artikel gefunden!
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Fluconazole
Artikelnummer: TGM-T1388-100mg
Description: Fluconazole (UK-49858) is a triazole antifungal agent used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS. Target: Antifungal, Antibiotic, Antifection. Smiles: OC(CN1C=NC=N1)(CN1C=NC=N1)C1=C(F)C=C(F)C=C1. References: Uppuluri P, et al. Antimicrob Agents Chemother, 2008, 52(3),...
| Schlagworte: | UK-49858 |
| Anwendung: | Targets sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36] (CYP51) |
| CAS | 86386-73-4 |
| MW: | 306.27 D |
ab 31,00 €
Tebuconazole
Artikelnummer: TGM-T17022-500mg
Description: Tebuconazole is an agricultural azole fungicide. It can also inhibit CYP51 (IC50s: 0.9 and 1.3 µM for Candida albicans CYP51 and truncated Homo sapiens CYP51, respectively). Target: Antifungal, P450. Smiles: CC(C)(C)C(O)(CCc1ccc(Cl)cc1)Cn1cncn1. References: Warrilow AG, et al. Azole affinity of sterol...
| Anwendung: | Conazole fungicide |
| CAS | 107534-96-3 |
| MW: | 307.82 D |
50,00 €
Lanoconazole
Artikelnummer: TGM-T15708-2mg
Description: Lanoconazole is an orally active imidazole antifungal agent that displays a broad spectrum of activity against fungi in vitro and in vivo. Lanoconazole interferes with ergosterol biosynthesis by inhibiting sterol 14-alpha demethylase and blocking fungal membrane ergosterol biosynthesis. Target:...
| Anwendung: | Targets sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36] (CYP51) |
| CAS | 101530-10-3 |
| MW: | 319.83 D |
49,00 €
Aliconazole
Artikelnummer: TGM-T14179-1mg
Description: Aliconazole is an imidazole derivative with antifungal activity for the study of skin infections. Target: Antifungal. Smiles: C(=C\C1=C(Cl)C=C(Cl)C=C1)(\CN2C=CN=C2)/C3=CC=C(Cl)C=C3. References: Fromtling RA, et al. Overview of medically important antifungal azole derivatives. Clin Microbiol Rev. 1988...
| Anwendung: | Targets sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36] (CYP51) |
| CAS | 63824-12-4 |
| MW: | 363.67 D |
ab 686,00 €
Butoconazole nitrate
Artikelnummer: TGM-T1438-100mg
Description: Butoconazole Nitrate is the nitrate salt form of butoconazole, a synthetic imidazole derivative with fungistatic properties. Butoconazole nitrate (RS 35887) interferes with steroid biosynthesis by inhibiting the conversion of lanosterol to ergosterol, thereby changing the fungal cell membrane lipid...
| Schlagworte: | RS 35887 |
| Anwendung: | Targets sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36] (CYP51) |
| CAS | 64872-77-1 |
| MW: | 474.79 D |
ab 33,00 €
Saperconazole
Artikelnummer: TGM-T16714-100mg
Description: Saperconazole is a broad-spectrum antifungal triazole (MIC90: 0.19 mg/L). Target: Others. Smiles: CCC(C)n1ncn(-c2ccc(cc2)N2CCN(CC2)c2ccc(OCC3COC(Cn4cncn4)(O3)c3ccc(F)cc3F)cc2)c1=O. References: Otcenásek M, et al. Susceptibility of clinical isolates of fungi to saperconazole. Mycopathologia. 1992...
| Schlagworte: | R66905 |
| Anwendung: | Targets sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36] (CYP51) |
| CAS | 110588-57-3 |
| MW: | 672.72 D |
ab 1.059,00 €
Azaconazole
Artikelnummer: TGM-T25126-25mg
Description: Azaconazole, an agricultural fungicide, is used for controlling powdery mildew on crops and bean rust. Target: Others. Smiles: ClC1=CC=C(C(Cl)=C1)C2(OCCO2)CN3N=CN=C3. References: Rankin GO, Yang DJ, Cressey-Veneziano K, Wang RT, Brown PI. In vivo and in vitro effects of azaconazole on renal function in...
| Schlagworte: | R-28644, Madurox, R 28644, R28644 |
| Anwendung: | Targets sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36] (CYP51) |
| CAS | 60207-31-0 |
| MW: | 300.14 D |
1.491,00 €
Propiconazole
Artikelnummer: TGM-T20595-10mg
Description: Propiconazole is an agricultural pesticide. Target: Others. Smiles: CCCC1COC(Cn2cncn2)(O1)c1ccc(Cl)cc1Cl. References: Mazur CS, Marchitti SA, Zastre J. P-glycoprotein inhibition by the agricultural pesticide propiconazole and its hydroxylated metabolites: Implications for pesticide-drug interactions....
| Schlagworte: | CGA-64250, CGA64250, Desmel, CGA 64250 |
| Anwendung: | Broad-spectrum triazole fungicide |
| CAS | 60207-90-1 |
| MW: | 342.22 D |
39,00 €
Oxiconazole
Artikelnummer: TGM-T20693-25mg
Description: Oxiconazole, an antifungal medicine, is used to treat certain kinds of yeast or fungal infections of the skin. Target: Others. Smiles: C(\CN1C=CN=C1)(=N\OCC2=C(Cl)C=C(Cl)C=C2)/C3=C(Cl)C=C(Cl)C=C3. References: NIkitina VV, Zakharova NB, Gladilin GP, Korshunov GV. [The impact of concentrations of nitric...
| Schlagworte: | Ro-13-8996, Ro 13-8996, Ro13-8996, Oxiconazolum |
| Anwendung: | Targets sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36] (CYP51) |
| CAS | 64211-45-6 |
| MW: | 429.13 D |
ab 1.491,00 €
Vibunazole
Artikelnummer: TGM-T35053-100mg
Description: Vibunazole is an antifungal agent. Target: Others. Smiles: C(CN1C=NC=N1)(COC2=CC=C(Cl)C=C2)(C(C)(C)C)O. References: van Gulpen C, Kelder O, Mattie H, van der Meer JW, van't Wout J. Pharmacokinetics of vibunazole (BAY n 7133) administered orally to healthy subjects. J Antimicrob Chemother. 1985...
| Schlagworte: | Bay N 7133, BayN 7133, Bay-N 7133 |
| Anwendung: | Targets sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36] (CYP51) |
| CAS | 80456-55-9 |
| MW: | 309.79 D |
ab 1.491,00 €
Diniconazole
Artikelnummer: TGM-T5952-100mg
Description: Diniconazole (Rac-diniconazole) is a fungicide. It is known as a plant hormone abscisic acid (ABA) catabolic inhibitor, and acts as a potent competitive inhibitor of recombinant Arabidopsis ABA 8'-hydroxylase, CYP707A3. Target: Antibacterial. Smiles: CC(C)(C)C(O)C(=C/c1ccc(Cl)cc1Cl)\n1cncn1. References:...
| Schlagworte: | Rac-diniconazole |
| Anwendung: | Broad-spectrum triazole fungicide |
| CAS | 83657-24-3 |
| MW: | 326.22 D |
ab 35,00 €
Hexaconazole
Artikelnummer: TGM-T5966-100mg
Description: Hexaconazole ((-)-Hexaconazol) is a broad-spectrum triazole fungicide that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14alpha-demethylation of lanosterol, which results in disruption of the fungal cell membrane and cell death. Target: Reactive Oxygen Species,...
| Schlagworte: | (-)-Hexaconazol |
| Anwendung: | Conazole fungicide |
| CAS | 79983-71-4 |
| MW: | 314.21 D |
ab 30,00 €