Zu "K05917" wurden 65 Artikel gefunden!
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Lanosterol 14-alpha-demethylase (human, recombinant)
Artikelnummer: Cay32928-50
Lanosterol 14-alpha-demethylase, also known as cytochrome P450 (CYP) isoform CYP51A1, is a heme-containing demethylase and member of the CYP450 superfamily that demethylates lanosterol (Cay-19521) to generate sterol precursors in the synthesis of cholesterol (Cay-39088, Cay-9003100). It is ubiquitously expressed...
| Schlagworte: | LDM, LDM, CYP51, CYPLI, CYPLI, CYP51A1, Cytochrome P450LI, Cytochrome P450LI, Cytochrome P45014DM, Cytochrome P45014DM,... |
| Anwendung: | Active enzyme |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
776,00 €
Lanosterol 14-alpha demethylase (cyp51), Mycobacterium...
Artikelnummer: CSB-BP006459MVZ.1
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh). Source: Baculovirus. Expression Region: 1-451aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MSAVALPRVS GGHDEHGHLE EFRTDPIGLM QRVRDECGDV GTFQLAGKQV VLLSGSHANE FFFRAGDDDL...
| Schlagworte: | cyp51, CYPLI, MT0788, Cytochrome P450 51, Cytochrome P450-LIA1, Cytochrome P450-14DM, Sterol 14alpha-demethylase, Sterol... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Insect cells |
| Ursprungsart: | Mycobacterium tuberculosis |
| MW: | 54.8 kD |
ab 474,00 €
Lanosterol 14-alpha demethylase (cyp51), Mycobacterium...
Artikelnummer: CSB-EP006459MVZ.1
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh). Source: E.coli. Expression Region: 1-451aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MSAVALPRVS GGHDEHGHLE EFRTDPIGLM QRVRDECGDV GTFQLAGKQV VLLSGSHANE FFFRAGDDDL DQAKAYPFMT PIFGEGVVFD ASPERRKEML...
| Schlagworte: | cyp51, CYPLI, MT0788, Cytochrome P450 51, Cytochrome P450-LIA1, Cytochrome P450-14DM, Sterol 14alpha-demethylase, Sterol... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | Mycobacterium tuberculosis |
| MW: | 56.8 kD |
ab 354,00 €
Lanosterol 14-alpha demethylase (ERG11), partial,...
Artikelnummer: CSB-EP006459SVG1.1
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). Source: E.coli. Expression Region: 1-20aa. Protein Length: Extracellular Domain. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MSATKSIVGE ALEYVNIGLS. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: Not test....
| Schlagworte: | ERG11, CYPLI, CYP51, YHR007C, EC=1.14.14.154, Cytochrome P450 51, Cytochrome P450-LIA1, Cytochrome P450-14DM, Sterol... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | Saccharomyces cerevisiae |
| MW: | 29.1 kD |
ab 354,00 €
Lanosterol 14-alpha demethylase (cyp51), Mycobacterium...
Artikelnummer: CSB-YP006459MVZa1.1
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh). Source: Yeast. Expression Region: 1-451aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MSAVALPRVS GGHDEHGHLE EFRTDPIGLM QRVRDECGDV GTFQLAGKQV VLLSGSHANE FFFRAGDDDL DQAKAYPFMT...
| Schlagworte: | cyp51, CYPLI, MT0788, Cytochrome P450 51, Cytochrome P450-LIA1, Cytochrome P450-14DM, Sterol 14alpha-demethylase, Sterol... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | Mycobacterium tuberculosis |
| MW: | 54.3 kD |
ab 395,00 €
Ketoconazole
Artikelnummer: Cay15212-100
Ketoconazole is a broad-spectrum triazole antifungal agent that has activity against C. albicans, C. krusei, C. tropicalis, C. glabrata, C. parapsilosis, C. neoformans, and A. fumigatus strains (IC50s = 0.031-8 µg/ml). It inhibits the fungal cytochrome P450 (CYP) isoform CYP51, also known as lanosterol...
| Schlagworte: | R 41400,... |
| Anwendung: | Cytochrome P450 inhibitor |
| CAS | 65277-42-1 |
| MW: | 531.4 D |
ab 77,00 €
Difenoconazole-d6 (hydrochloride)
Artikelnummer: Cay27834-1
Difenoconazole-d6 is intended for use as an internal standard for the quantification of difenoconazole (Cay-24053) by GC- or LC-MS. Difenoconazole is a triazole fungicide. It is active against eight F. graminearum isolates (EC50s = 1.69-19.6 mg/L) and A. sonali, F. fulva, B. cinerea, and R. solani (EC50s = 0.131,...
| Schlagworte: | 1-((2-(2-chloro-4-(4-chlorophenoxy)phenyl)-4-(methyl-d3)-1,3-dioxolan-2-yl-4,5,5-d3)methyl)-1H-1,2,4-triazole,... |
| Anwendung: | GC-MS, LC-MS, internal standard, conazole fungicide |
| CAS | 2748435-81-4 |
| MW: | 448.8 D |
158,00 €
Ketoconazole
Artikelnummer: LKT-K1676.5
An inhibitor of cytochrome P-450 in steroid biosynthesis, and an inhibitor of lipoxygenase and thromboxane synthase activities. It is classified as antineoplastic, antimetastatic, and antipsoriatic.
| Anwendung: | Cytochrome P-450 inhibitor |
| CAS | 65277-42-1 |
| MW: | 531,44 D |
ab 190,00 €
Fluconazole
Artikelnummer: Cay11594-500
Fluconazole is a triazole antifungal agent that is effective against most Candida strains. In vivo fluconazole at 0.5-100 mg/kg demonstrates protective activity in various experimental animal models of systemic fungal diseases including aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, cryptococcosis,...
| Schlagworte: | UK 49858, alpha-(2,4-difluorophenyl)-alpha-(1H-1,2,4-triazol-1-ylmethyl)-1H-1,2,4-triazole-1-ethanol |
| Anwendung: | Antifungal agent, CYP51 inhibitor |
| CAS | 86386-73-4 |
| MW: | 306.3 D |
ab 54,00 €
Posaconazole
Artikelnummer: Cay14737-10
Posaconazole is a broad-spectrum triazole antifungal agent active against various yeasts and molds, including Aspergillus, Candida, Fusarium, and Zygomycetes. Posaconazole inhibits the growth of fungi by inhibiting the lanosterol 14alpha-demethylase enzyme (IC50s = 7-200 nM), which results in a disruption in the...
| Schlagworte: | POS, SCH 56592,... |
| Anwendung: | Antifungal, Lanosterol 14a-demethylase inhibitor |
| CAS | 171228-49-2 |
| MW: | 700.8 D |
ab 82,00 €
Voriconazole-d3
Artikelnummer: Cay17803-1
Voriconazole-d3 is intended for use as an internal standard for the quantification of voriconazole (Cay-15633) by GC- or LC-MS. Voriconazole is a triazole antifungal agent and a derivative of fluconazole (Cay-11594). It is active against a variety of yeast and fungi, including clinical isolates of A. flavus, A....
| Schlagworte: | VRC-d3, (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-4,4,4-d3-2-ol |
| Anwendung: | Internal standard |
| MW: | 352.3 D |
ab 240,00 €
Imazalil-d5 (sulfate)
Artikelnummer: Cay39261-1
Imazalil-d5 (sulfate) is intended for use as an internal standard for the quantification of imazalil (Cay-25815) by GC- or LC-MS. Imazalil is an imidazole fungicide that inhibits ergosterol biosynthesis. Imazalil inhibits the growth of various fungi in vitro including P. italicum, A. niger, U. maydis, B. alii, and...
| Schlagworte: | (±)-Imazalil-d5, Enilconazole-d5, 1-(2-((allyl-d5)oxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole, monosulfate |
| Anwendung: | GC-MS, LC-MS internal standard, quantification, imidazole fungicide |
| CAS | 1398065-92-3 |
| MW: | 400.3 D |
ab 122,00 €