Zu "K05856" wurden 113 Artikel gefunden!
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NEU
Tyrosine-protein kinase Lck (LCK), human, recombinant
Artikelnummer: CSB-EP012806HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-539aa. Protein Length: Full Length of Isoform 3. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MGCGCSSHPE DDWMENIDVC ENCHYPIVPL DGKGTLLIRN GSEVRDPLVT YEGSNPPASP LQDNLVIALH SYEPSHDGDL GFEKGEQLRI LEQSGEWWKA QSLTTGQEGF IPFNFVAKAN...
| Schlagworte: | LSK, LCK, p56-LCK, EC=2.7.10.2, Protein YT16, Proto-oncogene Lck, Tyrosine-protein kinase Lck, Leukocyte C-terminal Src... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 65.2 kD |
ab 213,00 €
NEU
Tyrosine-protein kinase Lck (LCK), human, recombinant
Artikelnummer: CSB-EP012806HUa2.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-539aa. Protein Length: Full Length of Isoform 3. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: MGCGCSSHPE DDWMENIDVC ENCHYPIVPL DGKGTLLIRN GSEVRDPLVT YEGSNPPASP LQDNLVIALH SYEPSHDGDL GFEKGEQLRI LEQSGEWWKA QSLTTGQEGF IPFNFVAKAN...
| Schlagworte: | LSK, LCK, p56-LCK, EC=2.7.10.2, Protein YT16, Proto-oncogene Lck, Tyrosine-protein kinase Lck, Leukocyte C-terminal Src... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 77.2 kD |
ab 213,00 €
NEU
Anti-LCK
Artikelnummer: CSB-PA003142.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-LSK, Anti-LCK, Anti-p56-LCK, EC=2.7.10.2, Anti-Protein YT16, Anti-Proto-oncogene Lck, Anti-Tyrosine-protein kinase... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 106,00 €
NEU
Anti-LCK
Artikelnummer: CSB-PA009798.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-LSK, Anti-LCK, Anti-p56-LCK, EC=2.7.10.2, Anti-Protein YT16, Anti-Proto-oncogene Lck, Anti-Tyrosine-protein kinase... |
| Anwendung: | ELISA, WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
106,00 €
PP2
Artikelnummer: Cay13198-1
The Src family of non-receptor tyrosine kinases regulate cell adhesion, growth, and differentiation through activation of multiple intracellular signaling pathways. Normally inactive, Src kinases are transiently activated during mitosis and constitutively activated by abnormal mutations. PP2 is a potent, reversible,...
| Schlagworte: | AGL 1879, 3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Anwendung: | Tyrosine kinase inhibitor |
| CAS | 172889-27-9 |
| MW: | 301.8 D |
ab 43,00 €
PP1 (Src Inhibitor)
Artikelnummer: Cay14244-1
PP1 is a potent, reversible, ATP-competitive, and selective inhibitor of the Src family of protein tyrosine kinases. It inhibits p56lck (IC50 = 5 nM), p59fynT (IC50 = 6 nM), Hck (IC50 = 20 nM), and Src (IC50 = 170 nM) without significantly affecting the activity of EGFR kinase (IC50 = 250 nM), JAK2 (IC50 = 50 µM),...
| Schlagworte: | AGL 1872, EI 275, 1-(1,1-dimethylethyl)-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Anwendung: | Tyrosine kinase inhibitor |
| CAS | 172889-26-8 |
| MW: | 281.4 D |
ab 66,00 €
Anti-phospho-Lck (Tyr394)
Artikelnummer: ARG51643.50
Protein function: Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T- cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the...
| Schlagworte: | Anti-phospho-LCK, Anti-phospho-LSK, Anti-phospho-p56-LCK, EC=2.7.10.2, Anti-phospho-Protein YT16,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 436,00 €
PD 173955
Artikelnummer: Cay30618-5
PD 173955 is a tyrosine kinase inhibitor. It inhibits c-Src, Yes, and LCK (IC50s = 25, 22, and 5 nM, respectively), as well as Bcr-Abl and c-Kit (IC50s = 1-2 and 25 nM, respectively), and is selective for these kinases over the insulin receptor (InsR), alpha-FGFR, basic FGFR (bFGFR), PDGFR, and PKC. PD 173955 (5,000...
| Schlagworte: | 6-(2,6-dichlorophenyl)-8-methyl-2-[[3-(methylthio)phenyl]amino]-pyrido[2,3-d]pyrimidin-7(8H)-one |
| Anwendung: | Tyrosine kinase inhibitor |
| CAS | 260415-63-2 |
| MW: | 443.4 D |
ab 43,00 €
A-770041
Artikelnummer: Cay32854-5
A-770041 is an inhibitor of LCK kinase (IC50 = 0.147 µM). It is selective for LCK over other Src family tyrosine kinases including Src, Fyn, Fgr, HCK, and Tie2 (IC50s = 9.05, 44.1, 14.1, 1.22, and >50 µM, respectively). A-770041 induces dephosphorylation of LCK by SHP-1, inactivating LCK, in IgE/antigen-stimulated...
| Schlagworte: | N-[4-[1-[trans-4-(4-acetyl-1-piperazinyl)cyclohexyl]-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-2-methoxyphenyl]-1-methyl-1... |
| Anwendung: | LCK inhibitor |
| CAS | 869748-10-7 |
| MW: | 621.7 D |
ab 77,00 €
Anti-Lck (Clone: ABM18H9)
Artikelnummer: ABE-10-8003-100
Protein function: Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T- cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the...
| Schlagworte: | Anti-LCK, Anti-LSK, Anti-p56-LCK, EC=2.7.10.2, Anti-Protein YT16, Anti-Proto-oncogene Lck, Anti-Tyrosine-protein kinase... |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 149,00 €
Anomalin A
Artikelnummer: AG-CN2-0006-M001
Lck (p56lck, lymphocyte specific tyrosine kinase) inhibitor, Antioxidant, DPPH radical scavenger. Isolated from marine fungus Arthrinium sp.
| Schlagworte: | 2,3,6,8-Tetrahydroxy-1-methylxanthone |
| Anwendung: | Lck inhibitor |
| CAS | 548740-86-9 |
| MW: | 274,1 D |
132,00 €
Anti-phospho-Lck (Tyr505)
Artikelnummer: ARG51824.100
Protein function: Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T- cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the...
| Schlagworte: | Anti-phospho-LCK, Anti-phospho-LSK, Anti-phospho-p56-LCK, EC=2.7.10.2, Anti-phospho-Protein YT16,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 436,00 €